| Literature DB >> 3264152 |
G Amicosante1, A Oratore, N Franceschini, M Maccarrone, R Strom, M Galleni, J M Frère.
Abstract
Two chromosome-encoded beta-lactamases have been purified from Citrobacter diversus ULA-27. They exhibited slightly different isoelectric points (6.8 and 6.2) and very similar Mr values (congruent to 29,000). Their specificity spectrum was rather wide, since they hydrolysed some cephalosporins with kcat: values similar to those observed with the best penicillin substrates. Cloxacillin, methicillin and imipenem were hydrolysed very slowly. Hydrolysis of azthreonam could not be detected.Entities:
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Year: 1988 PMID: 3264152 PMCID: PMC1135165 DOI: 10.1042/bj2540885
Source DB: PubMed Journal: Biochem J ISSN: 0264-6021 Impact factor: 3.857