Literature DB >> 32640300

microRNAs in gastric cancer: biomarkers and therapeutic targets.

Soudeh Ghafouri-Fard1, Reza Vafaee2, Hamed Shoorei3, Mohammad Taheri4.   

Abstract

MicroRNAs (miRNAs) are a group of non-coding RNAs that have critical roles in regulation of expression of genes. They can inhibit or decrease expression of target genes mostly via interaction with 3' untranslated region of their targets. Their crucial roles in the regulation of expression of tumor suppressor genes and oncogenes have potentiated them as contributors in tumorigenesis. Moreover, their stability in body fluids has enhanced their potential as cancer biomarkers. In the present review article, we describe the role of miRNAs in the pathogenesis of gastric cancer and advances in application of miRNAs as biomarkers and therapeutic targets in this kind of malignancy.
Copyright © 2020 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  biomarker; gastric cancer; miRNA; therapeutic response

Year:  2020        PMID： 32640300     DOI： 10.1016/j.gene.2020.144937

Source DB:  PubMed          Journal:  Gene        ISSN： 0378-1119            Impact factor:   3.688


  9 in total

1.  Hsa-let-7d-5p Promotes Gastric Cancer Progression by Targeting PRDM5.

Authors:  Xiang Gao; Huiqi Liu; Rong Wang; Mingyu Huang; Qiong Wu; Yang Wang; Wei Zhang; Yongnian Liu
Journal:  J Oncol       Date:  2022-07-07       Impact factor: 4.501

2.  MiR-874-3p represses the migration and invasion yet promotes the apoptosis and cisplatin sensitivity via being sponged by long intergenic non-coding RNA 00922 (LINC00922) and targeting Glycerophosphodiester Phosphodiesterase Domain Containing 5 (GDPD5) in gastric cancer cells.

Authors:  Xiaoyu Zhang; Xudong Dai; Xin Zhao; Jian Wang; Jin Dou; Haiwen Zhuang; Ning Chen; Haijian Zhao
Journal:  Bioengineered       Date:  2022-03       Impact factor: 6.832

3.  Hub microRNAs and genes in the development of atrial fibrillation identified by weighted gene co-expression network analysis.

Authors:  Qiang Qu; Jin-Yu Sun; Zhen-Ye Zhang; Yue Su; Shan-Shan Li; Feng Li; Ru-Xing Wang
Journal:  BMC Med Genomics       Date:  2021-11-15       Impact factor: 3.063

4.  MiR-585-5p impedes gastric cancer proliferation and metastasis by orchestrating the interactions among CREB1, MAPK1 and MITF.

Authors:  Yunwei Wang; Ming Li; Jiaoxia Zeng; Yunshu Yang; Zengshan Li; Sijun Hu; Fangfang Yang; Na Wang; Wenlan Wang; Jun Tie
Journal:  Front Immunol       Date:  2022-10-04       Impact factor: 8.786

5.  Aberrant Non-Coding RNA Expressed in Gastric Cancer and Its Diagnostic Value.

Authors:  Zhilong Yu; ZeYin Rong; Jinxin Sheng; Zai Luo; Jianming Zhang; Tengfei Li; Zhonglin Zhu; Zhongmao Fu; Zhengjun Qiu; Chen Huang
Journal:  Front Oncol       Date:  2021-07-06       Impact factor: 6.244

6.  Predicting Associations of miRNAs and Candidate Gastric Cancer Genes for Nanomedicine.

Authors:  Aigul Akimniyazova; Anna Pyrkova; Vladimir Uversky; Anatoliy Ivashchenko
Journal:  Nanomaterials (Basel)       Date:  2021-03-10       Impact factor: 5.076

7.  lncRNA ACTA2-AS1 inhibits malignant phenotypes of gastric cancer cells.

Authors:  Zhiping Liu; Kaibing Hu; Xiang Wang; Youqian Zhang; Weiping Wang; Yindi Wu
Journal:  Open Med (Wars)       Date:  2022-02-15

8.  Bergamottin Induces DNA Damage and Inhibits Malignant Progression in Melanoma by Modulating miR-145/Cyclin D1 Axis.

Authors:  Zhongfang Zhao; Nong Liao
Journal:  Onco Targets Ther       Date:  2021-06-17       Impact factor: 4.147

9.  Circular RNA ZNF609 drives tumor progression by regulating the miR-138-5p/SIRT7 axis in melanoma.

Authors:  Quan Liu; Wei Cui; Chao Yang; Li-Ping Du
Journal:  Aging (Albany NY)       Date:  2021-08-09       Impact factor: 5.682
  9 in total

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