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Literature DB >> 3263618

Alteration of calcium sensitivity of skinned frog skeletal muscle fibres by inositol triphosphate and calmodulin antagonists.

Abstract

We investigated the influence of inositol triphosphate (IP3), trifluoperazine (TFP), and perhexiline on the calcium sensitivity of freeze-dried frog semitendinosus muscle fibres. Further, the effect of IP3 on calcium release from the sarcoplasmic reticulum (SR) of frog semitendinosus fibres skinned by saponin was studied. IP3 decreased the calcium sensitivity of freeze-dried frog skeletal muscle fibres and failed to induce a calcium release from SR of saponin-skinned fibres. Freeze-dried frog skeletal muscle fibres were strongly sensitized for calcium by TFP and perhexiline.

Entities: Chemical Disease Gene

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Year: 1988 PMID： 3263618 DOI： 10.1007/bf00582505

Source DB: PubMed Journal: Pflugers Arch ISSN： 0031-6768 Impact factor: 3.657

20 in total

1. Metofenazate as a more selective calmodulin inhibitor than trifluoperazine.

Authors: V A Tkachuk; G N Baldenkov; I A Feoktistov; M Y Men'shikov; U Quast; J W Herzig
Journal: Arzneimittelforschung Date: 1987-09

2. Inositol trisphosphate enhances calcium release in skinned cardiac and skeletal muscle.

Authors: T M Nosek; M F Williams; S T Zeigler; R E Godt
Journal: Am J Physiol Date: 1986-05

3. Calculator programs for computing the composition of the solutions containing multiple metals and ligands used for experiments in skinned muscle cells.

Authors: A Fabiato; F Fabiato
Journal: J Physiol (Paris) Date: 1979

4. The messenger across the gap.

Authors: A P Somlyo
Journal: Nature Date: 1985 Jul 25-31 Impact factor: 49.962

5. The effect of myosin phosphorylation on the contractile properties of skinned rabbit skeletal muscle fibers.

Authors: A Persechini; J T Stull; R Cooke
Journal: J Biol Chem Date: 1985-07-05 Impact factor: 5.157

Review 6. Calmodulin plays a pivotal role in cellular regulation.

Authors: W Y Cheung
Journal: Science Date: 1980-01-04 Impact factor: 47.728

7. Myofibrillar calcium sensitivity modulation: influence of light chain phosphorylation and positive inotropic drugs on skinned frog skeletal muscle.

Authors: I Morano; G Piazzesi; J C Rüegg
Journal: Adv Exp Med Biol Date: 1988 Impact factor: 2.622

2. Inositol trisphosphate (InsP3) causes contraction in skeletal muscle only under artificial conditions: evidence that Ca2+ release can result from depolarization of T-tubules.

Authors: J D Hannon; N K Lee; C Yandong; J R Blinks
Journal: J Muscle Res Cell Motil Date: 1992-08 Impact factor: 2.698

2 in total

Alteration of calcium sensitivity of skinned frog skeletal muscle fibres by inositol triphosphate and calmodulin antagonists.

1. Metofenazate as a more selective calmodulin inhibitor than trifluoperazine.

2. Inositol trisphosphate enhances calcium release in skinned cardiac and skeletal muscle.

3. Calculator programs for computing the composition of the solutions containing multiple metals and ligands used for experiments in skinned muscle cells.

4. The messenger across the gap.

5. The effect of myosin phosphorylation on the contractile properties of skinned rabbit skeletal muscle fibers.

Review 6. Calmodulin plays a pivotal role in cellular regulation.

7. Myofibrillar calcium sensitivity modulation: influence of light chain phosphorylation and positive inotropic drugs on skinned frog skeletal muscle.

8. Inositol 1,4,5-trisphosphate induces calcium release from sarcoplasmic reticulum of skeletal muscle.

9. Inositol 1,4,5-trisphosphate is not effective in releasing calcium from skeletal sarcoplasmic reticulum microsomes.

10. Inositol 1,4,5-trisphosphate: a possible chemical link in excitation-contraction coupling in muscle.

Review 1. Inositol trisphosphate and excitation-contraction coupling in skeletal muscle.

2. Inositol trisphosphate (InsP3) causes contraction in skeletal muscle only under artificial conditions: evidence that Ca2+ release can result from depolarization of T-tubules.