Literature DB >> 3262634

Differential diagnosis of solitary pulmonary nodules with positron emission tomography using [11C]L-methionine.

K Kubota1, T Matsuzawa, T Fujiwara, Y Abe, M Ito, J Hatazawa, T Ido, K Ishiwata, S Watanuki.   

Abstract

Two patients with solitary pulmonary nodules, 1.5-2.0 cm in diameter, were studied by positron emission tomography using [11C-Methyl]L-methionine (11C-Met). Case 1 showed high accumulation of 11C-Met in the tumor, and a tumor/muscle ratio of 6.0 suggesting malignancy. Tissue obtained by biopsy revealed a squamous cell carcinoma. Case 2 showed nonspecific isotope accumulation in the tumor, and a tumor/muscle ratio of 1.2 suggesting a benign lesion. Lung biopsy demonstrated granuloma. Positron emission tomography with 11C-Met seems to be useful for the differential diagnosis of solitary lung nodules.

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Year:  1988        PMID: 3262634     DOI: 10.1097/00004728-198809010-00015

Source DB:  PubMed          Journal:  J Comput Assist Tomogr        ISSN: 0363-8715            Impact factor:   1.826


  6 in total

1.  Metabolic fate of L-[methyl-11C]methionine in human plasma.

Authors:  K Ishiwata; J Hatazawa; K Kubota; M Kameyama; M Itoh; T Matsuzawa; T Takahashi; R Iwata; T Ido
Journal:  Eur J Nucl Med       Date:  1989

Review 2.  Tracer imaging in lung cancer.

Authors:  H M Abdel-Dayem; A Scott; H Macapinlac; S Larson
Journal:  Eur J Nucl Med       Date:  1994-01

3.  Pilot study of the utility of the synthetic PET amino-acid radiotracer anti-1-amino-3-[(18)F]fluorocyclobutane-1-carboxylic acid for the noninvasive imaging of pulmonary lesions.

Authors:  Rianot Amzat; Pooneh Taleghani; Daniel L Miller; Jonathan J Beitler; Leah M Bellamy; Jonathon A Nye; Weiping Yu; Bital Savir-Baruch; Adeboye O Osunkoya; Zhengjia Chen; William F Auffermann; Mark M Goodman; David M Schuster
Journal:  Mol Imaging Biol       Date:  2013-10       Impact factor: 3.488

Review 4.  Pulmonary nuclear medicine.

Authors:  R F Miller; M J O'Doherty
Journal:  Eur J Nucl Med       Date:  1992

5.  A comparison study of (11)C-methionine and (18)F-fluorodeoxyglucose positron emission tomography-computed tomography scans in evaluation of patients with recurrent brain tumors.

Authors:  Rajnish Sharma; Maria D'Souza; Abhinav Jaimini; Puja Panwar Hazari; Sanjeev Saw; Santosh Pandey; Dinesh Singh; Yachna Solanki; Nitin Kumar; Anil K Mishra; Anupam Mondal
Journal:  Indian J Nucl Med       Date:  2016 Apr-Jun

6.  Differential diagnosis of AH109A tumor and inflammation by radioscintigraphy with L-[methyl-11C]methionine.

Authors:  K Kubota; T Matsuzawa; T Fujiwara; T Sato; M Tada; T Ido; K Ishiwata
Journal:  Jpn J Cancer Res       Date:  1989-08
  6 in total

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