Literature DB >> 2806329

Metabolic fate of L-[methyl-11C]methionine in human plasma.

K Ishiwata1, J Hatazawa, K Kubota, M Kameyama, M Itoh, T Matsuzawa, T Takahashi, R Iwata, T Ido.   

Abstract

The metabolites of L-[methyl-11C]methionine in the plasma of 8 patients with tumors were measured for 60 min after injection. In the plasma, after a rapid clearance, the total radioactivity remained constant, and protein-bound radioactivity increased rapidly. Non protein metabolites detected by HPLC as at least two components besides methionine, increased with time. Significant individual variations for the metabolism were observed. At 60 min after injection, 36.5% (range: 16%-72%) and 45.3% (range: 13%-74%) of the 11C was measured as methionine and labeled proteins, respectively.

Entities:  

Mesh：

Substances：

Year:  1989        PMID： 2806329     DOI： 10.1007/bf00251681

Source DB:  PubMed          Journal:  Eur J Nucl Med        ISSN： 0340-6997


  18 in total

1.  Effect of dietary methionine level on its metabolism in rats.

Authors:  T S Aguilar; N J Benevenga; A E Harper
Journal:  J Nutr       Date:  1974-06       Impact factor: 4.798

2.  High in vivo rates of methionine biosynthesis in transformed human and malignant rat cells auxotrophic for methionine.

Authors:  R M Hoffman; R W Erbe
Journal:  Proc Natl Acad Sci U S A       Date:  1976-05       Impact factor: 11.205

3.  Non selective transport of [11C-methyl]-L-and D-methionine into a malignant glioma.

Authors:  O Schober; C Duden; G J Meyer; J A Müller; H Hundeshagen
Journal:  Eur J Nucl Med       Date:  1987

4.  Differential diagnosis of solitary pulmonary nodules with positron emission tomography using [11C]L-methionine.

Authors:  K Kubota; T Matsuzawa; T Fujiwara; Y Abe; M Ito; J Hatazawa; T Ido; K Ishiwata; S Watanuki
Journal:  J Comput Assist Tomogr       Date:  1988 Sep-Oct       Impact factor: 1.826

5.  Positron emission tomography with ([11C]methyl)-L-methionine, [11C]D-glucose, and [68Ga]EDTA in supratentorial tumors.

Authors:  K Ericson; A Lilja; M Bergström; V P Collins; L Eriksson; E Ehrin; H von Holst; H Lundqvist; B Långsrom B; M Mosskin
Journal:  J Comput Assist Tomogr       Date:  1985 Jul-Aug       Impact factor: 1.826

6.  PET study of methionine accumulation in glioma and normal brain tissue: competition with branched chain amino acids.

Authors:  M Bergström; K Ericson; L Hagenfeldt; M Mosskin; H von Holst; G Norén; L Eriksson; E Ehrin; P Johnström
Journal:  J Comput Assist Tomogr       Date:  1987 Mar-Apr       Impact factor: 1.826

7.  Brain tumor protein synthesis and histological grades: a study by positron emission tomography (PET) with C11-L-Methionine.

Authors:  P Bustany; M Chatel; J M Derlon; F Darcel; P Sgouropoulos; F Soussaline; A Syrota
Journal:  J Neurooncol       Date:  1986       Impact factor: 4.130

8.  Increased amounts of D-enantiomer dependent on alkaline concentration in the synthesis of L-[methyl-11C]methionine.

Authors:  K Ishiwata; T Ido; W Vaalburg
Journal:  Int J Rad Appl Instrum A       Date:  1988

9.  Assessment of [11C]-L-methionine transport into the human brain.

Authors:  L A O'Tuama; T R Guilarte; K H Douglass; H N Wagner; D F Wong; R F Dannals; H T Ravert; A A Wilson; N D LaFrance; A N Bice
Journal:  J Cereb Blood Flow Metab       Date:  1988-06       Impact factor: 6.200

10.  Dynamic study of supratentorial gliomas with L-methyl-11C-methionine and positron emission tomography.

Authors:  A Lilja; K Bergström; P Hartvig; B Spännare; C Halldin; H Lundqvist; B Långstrom
Journal:  AJNR Am J Neuroradiol       Date:  1985 Jul-Aug       Impact factor: 3.825
View more
  6 in total

1.  Dynamic study of methionine uptake in glioma using positron emission tomography.

Authors:  K Sato; M Kameyama; K Ishiwata; J Hatazawa; R Katakura; T Yoshimoto
Journal:  Eur J Nucl Med       Date:  1992

2.  Hepatic metabolism of 11C-methionine and secretion of 11C-protein measured by PET in pigs.

Authors:  Jacob Horsager; Susanne Bach Lausten; Dirk Bender; Ole Lajord Munk; Susanne Keiding
Journal:  Am J Nucl Med Mol Imaging       Date:  2017-09-01

Review 3.  From Carbon-11-Labeled Amino Acids to Peptides in Positron Emission Tomography: the Synthesis and Clinical Application.

Authors:  Aleksandra Pekošak; Ulrike Filp; Alex J Poot; Albert D Windhorst
Journal:  Mol Imaging Biol       Date:  2018-08       Impact factor: 3.488

4.  Improved detection and measurement of low levels of [18F]fluoride metabolized from [18F]-labeled pyrimidine nucleoside analogues in biological samples.

Authors:  Vincenzo Paolillo; Hsin Hsien Yeh; Uday Mukhopadhyay; Juri G Gelovani; Mian M Alauddin
Journal:  Nucl Med Biol       Date:  2011-07-08       Impact factor: 2.408

5.  Synthesis of enantiopure 18F-trifluoromethyl cysteine as a structure-mimetic amino acid tracer for glioma imaging.

Authors:  Shaoyu Liu; Hui Ma; Zhanwen Zhang; Liping Lin; Gongjun Yuan; Xiaolan Tang; Dahong Nie; Shende Jiang; Guang Yang; Ganghua Tang
Journal:  Theranostics       Date:  2019-01-30       Impact factor: 11.556

6.  Biological Evaluation of [18F]AlF-NOTA-NSC-GLU as a Positron Emission Tomography Tracer for Hepatocellular Carcinoma.

Authors:  Liping Lin; Xianhong Xiang; Shu Su; Shaoyu Liu; Ying Xiong; Hui Ma; Gongjun Yuan; Dahong Nie; Ganghua Tang
Journal:  Front Chem       Date:  2021-04-16       Impact factor: 5.221
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.