Literature DB >> 3262345

Effect of alpha-1-antichymotrypsin on activity of DNA primase isolated from human stomach adenocarcinoma cells.

S Takada1, M Tsuda, M Yamamura, T Katsunuma.   

Abstract

This paper describes an investigation into the effect of alpha-1-antichymotrypsin (ACT) on DNA primase. DNA primase was partially purified from human stomach carcinoma cells. It was found that poly(dC)-dependent DNa primase activity was inhibited by ACT and the inhibition was proportional to the concentration of the inhibitor. The inhibitory effect of ACT remained even after ACT lost most of its chymotrypsin-inhibitory activity by heat treatment. Poly(dT)-dependent primase activity was enhanced by the presence of ACT. The enhancement was effective up to a concentration of 1mg/ml.

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Year:  1988        PMID： 3262345

Source DB:  PubMed          Journal:  Biochem Int        ISSN： 0158-5231


  2 in total

1.  Alpha-1-antichymotrypsin variant detected by PCR-single strand conformation polymorphism (PCR-SSCP) and direct sequencing.

Authors:  M Tsuda; Y Sei; M Matsumoto; H Kamiguchi; M Yamamoto; Y Shinohara; T Igarashi; M Yamamura
Journal:  Hum Genet       Date:  1992-12       Impact factor: 4.132

2.  SerpinA3N is a novel hypothalamic gene upregulated by a high-fat diet and leptin in mice.

Authors:  Domenico Sergi; Fiona M Campbell; Christine Grant; Amanda C Morris; Eva-Maria Bachmair; Christiane Koch; Fiona H McLean; Aifric Muller; Nigel Hoggard; Baukje de Roos; Begona Porteiro; Mark V Boekschoten; Fiona C McGillicuddy; Darcy Kahn; Phyllis Nicol; Jonas Benzler; Claus-Dieter Mayer; Janice E Drew; Helen M Roche; Michael Muller; Ruben Nogueiras; Carlos Dieguez; Alexander Tups; Lynda M Williams
Journal:  Genes Nutr       Date:  2018-11-29       Impact factor: 5.523
  2 in total

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