Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Alterations of acyl-neuraminic acids on T-lymphocytes in cases of melanoma.

Literature DB >> 3262185

Alterations of acyl-neuraminic acids on T-lymphocytes in cases of melanoma.

R Holzhauser¹, H Faillard, W Klose, W Huber, H Stickl, M Landthaler.

Abstract

Content and distribution of the different sialic acids on human lymphocytes, isolated from 7-10 ml of fresh human blood, were determined using microanalytical methods, such as HPLC and a colorimetric test. Comparison of the data of patients with melanoma with those of healthy persons shows an evident increase of the sialic acid content combined with a shift of the sialic acid distribution to higher O-acetylated derivatives.

Entities: Chemical Disease Species

Mesh：

Substances：
Sialic Acids

Year: 1988 PMID： 3262185 DOI： 10.1007/bf01736523

Source DB: PubMed Journal: Klin Wochenschr ISSN： 0023-2173

22 in total

1. [Elevated serum-sialyltransferase activity in human malignant diseases: a new diagnostic tool? (author's transl)].

Authors: U Ganzinger; F Dorner; F M Unger; K Moser; K Jentzsch
Journal: Klin Wochenschr Date: 1977-06-01

2. Lymphocyte membrane alterations caused by nylon wool column separation.

Authors: A Corrigan; R O'Kennedy; H Smyth
Journal: J Immunol Methods Date: 1979 Impact factor: 2.303

Review 3. The significance of glycosylated proteins.

Authors: P J Winterburn; C F Phelps
Journal: Nature Date: 1972-03-24 Impact factor: 49.962

4. Serum sialic acid concentrations in malignant melanoma.

Authors: A H Ryan; J J Fennelly
Journal: Eur J Cancer Clin Oncol Date: 1981-07

Review 5. Identifying and enumerating human T and B lymphocytes. A review of techniques, problems, and progress in clinical studies.

Authors: J M Dwyer
Journal: Prog Allergy Date: 1976

3. 9-O-Acetylation of sialomucins: a novel marker of murine CD4 T cells that is regulated during maturation and activation.

Authors: M Krishna; A Varki
Journal: J Exp Med Date: 1997-06-02 Impact factor: 14.307

4. Natural ligands of the B cell adhesion molecule CD22 beta can be masked by 9-O-acetylation of sialic acids.

Authors: E R Sjoberg; L D Powell; A Klein; A Varki
Journal: J Cell Biol Date: 1994-07 Impact factor: 10.539

4 in total

Alterations of acyl-neuraminic acids on T-lymphocytes in cases of melanoma.

1. [Elevated serum-sialyltransferase activity in human malignant diseases: a new diagnostic tool? (author's transl)].

2. Lymphocyte membrane alterations caused by nylon wool column separation.

Review 3. The significance of glycosylated proteins.

4. Serum sialic acid concentrations in malignant melanoma.

Review 5. Identifying and enumerating human T and B lymphocytes. A review of techniques, problems, and progress in clinical studies.

6. Sialic acid metabolism in nutritionally modulated mammary gland carcinogenesis.

7. Prediction of malignant melanoma recurrence by serum N-acetylneuraminic acid.

8. Differences in sialic acid contents of low cancer cells, high cancer cells and normal mouse lung counterparts.

9. Increased sialic acid in "blocked" lymphocytes and correlation of spontaneous release with clinical state.

10. Serum sialic acid in normals and in cancer patients.

1. [Change in acylneuraminic acid content of T-lymphocytes and in plasma in breast cancer].

2. Total and ganglioside-bound sialic acid content of lymphocytes from non-insulin-dependent diabetic patients.

3. 9-O-Acetylation of sialomucins: a novel marker of murine CD4 T cells that is regulated during maturation and activation.

4. Natural ligands of the B cell adhesion molecule CD22 beta can be masked by 9-O-acetylation of sialic acids.