Literature DB >> 3261675

Antinuclear antibodies in scleroderma, mixed connective tissue disease and "primary" Raynaud's phenomenon.

M Cruz1, G Mejia, C Lavalle, J J Cortes, P A Reyes.   

Abstract

The diversity of antibodies in patients with scleroderma, mixed connective tissue disease or "primary" Raynaud's phenomenon could be used as a laboratory aid in the clinical diagnosis. In serum samples of 75 patients we screened for antinuclear antibodies (HEp 2 cells), anti DNA, soluble nucleoprotein and extractable nuclear antigens (Sm, rRNP, U1-nRNP, SSA/Ro, SSB/La and Scl-70). Distinctive antinuclear antibodies pattern was identified in each group of patients. This immunologic profile is valuable for clinical diagnosis and the preferential association of certain autoantibodies with some diseases and not with others, suggest an antigen-driven stimulus for its production.

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Year:  1988        PMID： 3261675     DOI： 10.1007/bf02284061

Source DB:  PubMed          Journal:  Clin Rheumatol        ISSN： 0770-3198            Impact factor:   2.980


  27 in total

1.  Profiles of antinuclear antibodies in systemic rheumatic diseases.

Authors:  D D Notman; N Kurata; E M Tan
Journal:  Ann Intern Med       Date:  1975-10       Impact factor: 25.391

2.  Immune-complex glomerulonephritis in a patient with mixed connective tissue disease.

Authors:  T J Fuller; A V Richman; D Auerbach; R W Alexander; R Lottenberg; S Longley
Journal:  Am J Med       Date:  1977-05       Impact factor: 4.965

3.  CRST syndrome. A benign variant of scleroderma.

Authors:  R D Carr; E B Heisel; T D Stevenson
Journal:  Arch Dermatol       Date:  1965-11

4.  Evolution of primary Raynaud's phenomenon (Raynaud's disease) to connective tissue disease.

Authors:  D D Gerbracht; V D Steen; G L Ziegler; T A Medsger; G P Rodnan
Journal:  Arthritis Rheum       Date:  1985-01

5.  Mixed connective tissue disease: a subsequent evaluation of the original 25 patients.

Authors:  S H Nimelstein; S Brody; D McShane; H R Holman
Journal:  Medicine (Baltimore)       Date:  1980-07       Impact factor: 1.889

6.  Antibodies to small nuclear RNAs complexed with proteins are produced by patients with systemic lupus erythematosus.

Authors:  M R Lerner; J A Steitz
Journal:  Proc Natl Acad Sci U S A       Date:  1979-11       Impact factor: 11.205

7.  Preliminary criteria for the classification of systemic sclerosis (scleroderma). Subcommittee for scleroderma criteria of the American Rheumatism Association Diagnostic and Therapeutic Criteria Committee.

Authors: 
Journal:  Arthritis Rheum       Date:  1980-05

8.  Autoantibody to centromere (kinetochore) in scleroderma sera.

Authors:  Y Moroi; C Peebles; M J Fritzler; J Steigerwald; E M Tan
Journal:  Proc Natl Acad Sci U S A       Date:  1980-03       Impact factor: 11.205

9.  The CREST syndrome: a distinct serologic entity with anticentromere antibodies.

Authors:  M J Fritzler; T D Kinsella
Journal:  Am J Med       Date:  1980-10       Impact factor: 4.965

10.  Association between fluorescent antinuclear antibodies, capillary patterns, and clinical features in scleroderma spectrum disorders.

Authors:  Z Y Chen; R M Silver; S K Ainsworth; R L Dobson; P Rust; H R Maricq
Journal:  Am J Med       Date:  1984-11       Impact factor: 4.965
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  4 in total

Review 1.  Rheumatology.

Authors:  R A Asherson; R Cervera; D P D'Cruz; G R Hughes
Journal:  Postgrad Med J       Date:  1991-02       Impact factor: 2.401

Review 2.  Raynaud's phenomenon: its relevance to scleroderma.

Authors:  J J Belch
Journal:  Ann Rheum Dis       Date:  1991-11       Impact factor: 19.103

3.  Frequent coexistence of anti-topoisomerase I and anti-U1RNP autoantibodies in African American patients associated with mild skin involvement: a retrospective clinical study.

Authors:  Minoru Satoh; Malgorzata E Krzyszczak; Yi Li; Angela Ceribelli; Steven J Ross; Edward K L Chan; Mark S Segal; Michael R Bubb; Eric S Sobel; Westley H Reeves
Journal:  Arthritis Res Ther       Date:  2011-05-10       Impact factor: 5.156

4.  Gender and ethnicity differences in the prevalence of scleroderma-related autoantibodies.

Authors:  Malgorzata E Krzyszczak; Yi Li; Steven J Ross; Angela Ceribelli; Edward K L Chan; Michael R Bubb; Eric S Sobel; Westley H Reeves; Minoru Satoh
Journal:  Clin Rheumatol       Date:  2011-04-27       Impact factor: 2.980
  4 in total

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