Literature DB >> 32610691

The seed of industrial hemp (Cannabis sativa L.): Nutritional Quality and Potential Functionality for Human Health and Nutrition.

Barbara Farinon1, Romina Molinari1, Lara Costantini1, Nicolò Merendino1.   

Abstract

n class="Chemical">pan class="Chemical">Hempseedspan>>, the edible fruits of the pan>n class="Species">Cannabis sativa L. plant, were initially considered a by-product of the hemp technical fibre industry. Nowadays, following the restorationing of the cultivation of C. sativa L. plants containing an amount of delta-9-tetrahydrocannabinol (THC) <0.3% or 0.2% (industrial hemp) there is a growing interest for the hempseeds production due to their high nutritional value and functional features. The goal of this review is to examine the scientific literature concerning the nutritional and functional properties of hempseeds. Furthermore, we revised the scientific literature regarding the potential use of hempseeds and their derivatives as a dietary supplement for the prevention and treatment of inflammatory and chronic-degenerative diseases on animal models and humans too. In the first part of the work, we provide information regarding the genetic, biochemical, and legislative aspects of this plant that are, in our opinion essential to understand the difference between "industrial" and "drug-type" hemp. In the final part of the review, the employment of hempseeds by the food industry as livestock feed supplement and as ingredient to enrich or fortify daily foods has also revised. Overall, this review intends to encourage further and comprehensive investigations about the adoption of hempseeds in the functional foods field.

Entities:  

Keywords:  Cannabis sativa L. legislation; THC; antinutritional compounds; bioactive peptides; hempseed dietary supplementation; hempseed minerals; hempseed oil; hempseed proteins; hempseed-based food; phenylpropionammides

Year:  2020        PMID: 32610691      PMCID: PMC7400098          DOI: 10.3390/nu12071935

Source DB:  PubMed          Journal:  Nutrients        ISSN: 2072-6643            Impact factor:   5.717


  97 in total

1.  Identification of olivetolic acid cyclase from Cannabis sativa reveals a unique catalytic route to plant polyketides.

Authors:  Steve J Gagne; Jake M Stout; Enwu Liu; Zakia Boubakir; Shawn M Clark; Jonathan E Page
Journal:  Proc Natl Acad Sci U S A       Date:  2012-07-16       Impact factor: 11.205

2.  Prenylation of olivetolate by a hemp transferase yields cannabigerolic acid, the precursor of tetrahydrocannabinol.

Authors:  M Fellermeier; M H Zenk
Journal:  FEBS Lett       Date:  1998-05-08       Impact factor: 4.124

3.  Efficacy of dietary hempseed oil in patients with atopic dermatitis.

Authors:  James Callaway; Ursula Schwab; Ilkka Harvima; Pirjo Halonen; Otto Mykkänen; Pekka Hyvönen; Tomi Järvinen
Journal:  J Dermatolog Treat       Date:  2005-04       Impact factor: 3.359

4.  Development, validation and application of a LC-MS/MS method for quantification of 15 cannabinoids in food.

Authors:  Nicolas Christinat; Marie-Claude Savoy; Pascal Mottier
Journal:  Food Chem       Date:  2020-02-24       Impact factor: 7.514

5.  Sequence heterogeneity of cannabidiolic- and tetrahydrocannabinolic acid-synthase in Cannabis sativa L. and its relationship with chemical phenotype.

Authors:  Chiara Onofri; Etienne P M de Meijer; Giuseppe Mandolino
Journal:  Phytochemistry       Date:  2015-04-09       Impact factor: 4.072

6.  Hempseed Peptides Exert Hypocholesterolemic Effects with a Statin-Like Mechanism.

Authors:  Chiara Zanoni; Gilda Aiello; Anna Arnoldi; Carmen Lammi
Journal:  J Agric Food Chem       Date:  2017-10-02       Impact factor: 5.279

7.  Nutritional and Phytochemical Content of High-Protein Crops.

Authors:  Salvatore Multari; Madalina Neacsu; Lorraine Scobbie; Louise Cantlay; Gary Duncan; Nicholas Vaughan; Derek Stewart; Wendy R Russell
Journal:  J Agric Food Chem       Date:  2016-10-11       Impact factor: 5.279

8.  Bioactive constituents from cinnamon, hemp seed and polygonum cuspidatum protect against H2O2 but not rotenone toxicity in a cellular model of Parkinson's disease.

Authors:  Suzanne A Maiolo; Peihong Fan; Larisa Bobrovskaya
Journal:  J Tradit Complement Med       Date:  2018-04-30

9.  Regulatory effects of hemp seed/evening primrose oil supplement in comparison with rapamycin on the expression of the mammalian target of rapamycin-complex 2 and interleukin-10 genes in experimental autoimmune encephalomyelitis.

Authors:  Soheila Rezapour-Firouzi; Fatemeh Kheradmand; Shahram Shahabi; Ali Asghar Tehrani; Ebrahim Mazloomi; Adel Mohammadzadeh
Journal:  Res Pharm Sci       Date:  2019-02

10.  Comparative Study of Chemical, Biochemical Characteristic and ATR-FTIR Analysis of Seeds, Oil and Flour of the Edible Fedora Cultivar Hemp (Cannabis sativa L.).

Authors:  Francesco Siano; Stefania Moccia; Gianluca Picariello; Gian Luigi Russo; Giuseppe Sorrentino; Michele Di Stasio; Francesco La Cara; Maria Grazia Volpe
Journal:  Molecules       Date:  2018-12-27       Impact factor: 4.411

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  22 in total

1.  Quality of Oil Pressed from Hemp Seed Varieties: 'Earlina 8FC', 'Secuieni Jubileu' and 'Finola'.

Authors:  Wojciech Golimowski; Mirosława Teleszko; Damian Marcinkowski; Dominik Kmiecik; Anna Grygier; Andrzej Kwaśnica
Journal:  Molecules       Date:  2022-05-16       Impact factor: 4.927

Review 2.  Differentiating Cannabis Products: Drugs, Food, and Supplements.

Authors:  Arash Salehi; Keely Puchalski; Yalda Shokoohinia; Behzad Zolfaghari; Sedigheh Asgary
Journal:  Front Pharmacol       Date:  2022-06-27       Impact factor: 5.988

3.  Effect of lignin-blocking agent on enzyme hydrolysis of acid pretreated hemp waste.

Authors:  Daehwan Kim; Chang Geun Yoo; Jurgen Schwarz; Sadanand Dhekney; Robert Kozak; Craig Laufer; Drew Ferrier; Skylar Mackay; Madyson Ashcraft; Richard Williams; Sinyeon Kim
Journal:  RSC Adv       Date:  2021-06-22       Impact factor: 4.036

Review 4.  Hemp and Its Derivatives as a Universal Industrial Raw Material (with Particular Emphasis on the Polymer Industry)-A Review.

Authors:  Karol Tutek; Anna Masek
Journal:  Materials (Basel)       Date:  2022-03-31       Impact factor: 3.623

5.  Impact of Enzymatic and Microbial Bioprocessing on Antioxidant Properties of Hemp (Cannabis sativa L.).

Authors:  Erica Pontonio; Michela Verni; Cinzia Dingeo; Elixabet Diaz-de-Cerio; Daniela Pinto; Carlo Giuseppe Rizzello
Journal:  Antioxidants (Basel)       Date:  2020-12-10

6.  Biochemical aspects of seeds from Cannabis sativa L. plants grown in a mountain environment.

Authors:  Chiara Cattaneo; Annalisa Givonetti; Valeria Leoni; Nicoletta Guerrieri; Marcello Manfredi; Annamaria Giorgi; Maria Cavaletto
Journal:  Sci Rep       Date:  2021-02-16       Impact factor: 4.379

7.  Antioxidant Activity of Hemp (Cannabis sativa L.) Seed Oil in Drosophila melanogaster Larvae under Non-Stress and H2O2-Induced Oxidative Stress Conditions.

Authors:  Jelena Vitorović; Nataša Joković; Niko Radulović; Tatjana Mihajilov-Krstev; Vladimir J Cvetković; Nikola Jovanović; Tatjana Mitrović; Ana Aleksić; Nemanja Stanković; Nirit Bernstein
Journal:  Antioxidants (Basel)       Date:  2021-05-22

8.  Advanced Characterization of Hemp Flour (Cannabis sativa L.) from Dacia Secuieni and Zenit Varieties, Compared to Wheat Flour.

Authors:  Iulian-Eugen Rusu; Romina Alina Marc Vlaic; Crina Carmen Mureşan; Andruţa Elena Mureşan; Miuţa Rafila Filip; Bogdan-Mihai Onica; Kádár Balázs Csaba; Ersilia Alexa; Lidia Szanto; Sevastiţa Muste
Journal:  Plants (Basel)       Date:  2021-06-18

Review 9.  Cancer Initiation, Progression and Resistance: Are Phytocannabinoids from Cannabis sativa L. Promising Compounds?

Authors:  Ersilia Nigro; Marialuisa Formato; Giuseppina Crescente; Aurora Daniele
Journal:  Molecules       Date:  2021-05-02       Impact factor: 4.411

Review 10.  It Is Our Turn to Get Cannabis High: Put Cannabinoids in Food and Health Baskets.

Authors:  Seyed Alireza Salami; Federico Martinelli; Antonio Giovino; Ava Bachari; Neda Arad; Nitin Mantri
Journal:  Molecules       Date:  2020-09-04       Impact factor: 4.927

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