Literature DB >> 32606465

CRISPR gene editing in human embryos wreaks chromosomal mayhem.

Heidi Ledford.   

Abstract

Entities:  

Keywords:  Biological techniques; CRISPR-Cas9 genome editing; Genetics

Mesh：

Substances：

Year:  2020        PMID： 32606465     DOI： 10.1038/d41586-020-01906-4

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  4 in total

1.  Correction of a pathogenic gene mutation in human embryos.

Authors:  Hong Ma; Nuria Marti-Gutierrez; Sang-Wook Park; Jun Wu; Yeonmi Lee; Keiichiro Suzuki; Amy Koski; Dongmei Ji; Tomonari Hayama; Riffat Ahmed; Hayley Darby; Crystal Van Dyken; Ying Li; Eunju Kang; A-Reum Park; Daesik Kim; Sang-Tae Kim; Jianhui Gong; Ying Gu; Xun Xu; David Battaglia; Sacha A Krieg; David M Lee; Diana H Wu; Don P Wolf; Stephen B Heitner; Juan Carlos Izpisua Belmonte; Paula Amato; Jin-Soo Kim; Sanjiv Kaul; Shoukhrat Mitalipov
Journal:  Nature       Date:  2017-08-02       Impact factor: 49.962

2.  Inter-homologue repair in fertilized human eggs?

Authors:  Dieter Egli; Michael V Zuccaro; Michael Kosicki; George M Church; Allan Bradley; Maria Jasin
Journal:  Nature       Date:  2018-08-08       Impact factor: 49.962

3.  Large deletions induced by Cas9 cleavage.

Authors:  Fatwa Adikusuma; Sandra Piltz; Mark A Corbett; Michelle Turvey; Shaun R McColl; Karla J Helbig; Michael R Beard; James Hughes; Richard T Pomerantz; Paul Q Thomas
Journal:  Nature       Date:  2018-08-08       Impact factor: 49.962

4.  Repair of double-strand breaks induced by CRISPR-Cas9 leads to large deletions and complex rearrangements.

Authors:  Michael Kosicki; Kärt Tomberg; Allan Bradley
Journal:  Nat Biotechnol       Date:  2018-07-16       Impact factor: 54.908
  4 in total
  8 in total

1.  Precise genome engineering in Drosophila using prime editing.

Authors:  Justin A Bosch; Gabriel Birchak; Norbert Perrimon
Journal:  Proc Natl Acad Sci U S A       Date:  2021-01-05       Impact factor: 11.205

2.  CRISPRroots: on- and off-target assessment of RNA-seq data in CRISPR-Cas9 edited cells.

Authors:  Giulia I Corsi; Veerendra P Gadekar; Jan Gorodkin; Stefan E Seemann
Journal:  Nucleic Acids Res       Date:  2022-02-28       Impact factor: 16.971

Review 3.  Deciphering DNA Methylation in HIV Infection.

Authors:  Thilona Arumugam; Upasana Ramphal; Theolan Adimulam; Romona Chinniah; Veron Ramsuran
Journal:  Front Immunol       Date:  2021-12-02       Impact factor: 7.561

4.  Effective control of large deletions after double-strand breaks by homology-directed repair and dsODN insertion.

Authors:  Wei Wen; Zi-Jun Quan; Si-Ang Li; Zhi-Xue Yang; Ya-Wen Fu; Feng Zhang; Guo-Hua Li; Mei Zhao; Meng-Di Yin; Jing Xu; Jian-Ping Zhang; Tao Cheng; Xiao-Bing Zhang
Journal:  Genome Biol       Date:  2021-08-20       Impact factor: 13.583

Review 5.  CRISPR-Cas and Its Wide-Ranging Applications: From Human Genome Editing to Environmental Implications, Technical Limitations, Hazards and Bioethical Issues.

Authors:  Roberto Piergentili; Alessandro Del Rio; Fabrizio Signore; Federica Umani Ronchi; Enrico Marinelli; Simona Zaami
Journal:  Cells       Date:  2021-04-21       Impact factor: 7.666

6.  Correction of RNA splicing defect in β654-thalassemia mice using CRISPR/Cas9 gene-editing technology.

Authors:  Dan Lu; Xiuli Gong; Yudan Fang; Xinbing Guo; Yanwen Chen; Fan Yang; Guijun Zhao; Qingwen Ma; Yitao Zeng; Fanyi Zeng
Journal:  Haematologica       Date:  2022-06-01       Impact factor: 11.047

7.  Days of Future Past: Reply to Open Peer Commentaries on "Revising, Correcting, and Transferring Genes".

Authors:  Bryan Cwik
Journal:  Am J Bioeth       Date:  2020-08       Impact factor: 11.229

8.  Homozygous might be hemizygous: CRISPR/Cas9 editing in iPSCs results in detrimental on-target defects that escape standard quality controls.

Authors:  Dina Simkin; Vasileios Papakis; Bernabe I Bustos; Christina M Ambrosi; Steven J Ryan; Valeriya Baru; Luis A Williams; Graham T Dempsey; Owen B McManus; John E Landers; Steven J Lubbe; Alfred L George; Evangelos Kiskinis
Journal:  Stem Cell Reports       Date:  2022-03-10       Impact factor: 7.294
  8 in total

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