Literature DB >> 32604012

The importance of including ethnically diverse populations in studies of quantitative trait evolution.

Michael A McQuillan1, Chao Zhang1, Sarah A Tishkoff2, Alexander Platt3.   

Abstract

For many traits, human variation is less a matter of categorical differences than quantitative variation, such as height, where individuals fall along a continuum from short to tall. Most recent studies utilize large population-based samples with whole-genome sequences to study the evolution of these traits and have made significant progress implementing a broad spectrum of techniques. However, relatively few studies of quantitative trait evolution include ethnically diverse populations, which often harbor the highest levels of genetic and phenotypic diversity. Thus, our ability to draw inferences about quantitative trait adaptation has been limited. Here, we review recent studies examining human quantitative trait adaptation, and argue that including ethnically diverse populations, particularly from Africa, will be especially informative for our understanding of how humans adapt to the world around them.
Copyright © 2020 Elsevier Ltd. All rights reserved.

Entities:  

Year:  2020        PMID: 32604012     DOI: 10.1016/j.gde.2020.05.037

Source DB:  PubMed          Journal:  Curr Opin Genet Dev        ISSN: 0959-437X            Impact factor:   5.578


  41 in total

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Authors:  Alessia Ranciaro; Michael C Campbell; Jibril B Hirbo; Wen-Ya Ko; Alain Froment; Paolo Anagnostou; Maritha J Kotze; Muntaser Ibrahim; Thomas Nyambo; Sabah A Omar; Sarah A Tishkoff
Journal:  Am J Hum Genet       Date:  2014-03-13       Impact factor: 11.025

2.  The NIH Roadmap Epigenomics Mapping Consortium.

Authors:  Bradley E Bernstein; John A Stamatoyannopoulos; Joseph F Costello; Bing Ren; Aleksandar Milosavljevic; Alexander Meissner; Manolis Kellis; Marco A Marra; Arthur L Beaudet; Joseph R Ecker; Peggy J Farnham; Martin Hirst; Eric S Lander; Tarjei S Mikkelsen; James A Thomson
Journal:  Nat Biotechnol       Date:  2010-10       Impact factor: 54.908

3.  The genetic structure and history of Africans and African Americans.

Authors:  Sarah A Tishkoff; Floyd A Reed; Françoise R Friedlaender; Christopher Ehret; Alessia Ranciaro; Alain Froment; Jibril B Hirbo; Agnes A Awomoyi; Jean-Marie Bodo; Ogobara Doumbo; Muntaser Ibrahim; Abdalla T Juma; Maritha J Kotze; Godfrey Lema; Jason H Moore; Holly Mortensen; Thomas B Nyambo; Sabah A Omar; Kweli Powell; Gideon S Pretorius; Michael W Smith; Mahamadou A Thera; Charles Wambebe; James L Weber; Scott M Williams
Journal:  Science       Date:  2009-04-30       Impact factor: 47.728

4.  Genome-wide detection and characterization of positive selection in human populations.

Authors:  Pardis C Sabeti; Patrick Varilly; Ben Fry; Jason Lohmueller; Elizabeth Hostetter; Chris Cotsapas; Xiaohui Xie; Elizabeth H Byrne; Steven A McCarroll; Rachelle Gaudet; Stephen F Schaffner; Eric S Lander; Kelly A Frazer; Dennis G Ballinger; David R Cox; David A Hinds; Laura L Stuve; Richard A Gibbs; John W Belmont; Andrew Boudreau; Paul Hardenbol; Suzanne M Leal; Shiran Pasternak; David A Wheeler; Thomas D Willis; Fuli Yu; Huanming Yang; Changqing Zeng; Yang Gao; Haoran Hu; Weitao Hu; Chaohua Li; Wei Lin; Siqi Liu; Hao Pan; Xiaoli Tang; Jian Wang; Wei Wang; Jun Yu; Bo Zhang; Qingrun Zhang; Hongbin Zhao; Hui Zhao; Jun Zhou; Stacey B Gabriel; Rachel Barry; Brendan Blumenstiel; Amy Camargo; Matthew Defelice; Maura Faggart; Mary Goyette; Supriya Gupta; Jamie Moore; Huy Nguyen; Robert C Onofrio; Melissa Parkin; Jessica Roy; Erich Stahl; Ellen Winchester; Liuda Ziaugra; David Altshuler; Yan Shen; Zhijian Yao; Wei Huang; Xun Chu; Yungang He; Li Jin; Yangfan Liu; Yayun Shen; Weiwei Sun; Haifeng Wang; Yi Wang; Ying Wang; Xiaoyan Xiong; Liang Xu; Mary M Y Waye; Stephen K W Tsui; Hong Xue; J Tze-Fei Wong; Luana M Galver; Jian-Bing Fan; Kevin Gunderson; Sarah S Murray; Arnold R Oliphant; Mark S Chee; Alexandre Montpetit; Fanny Chagnon; Vincent Ferretti; Martin Leboeuf; Jean-François Olivier; Michael S Phillips; Stéphanie Roumy; Clémentine Sallée; Andrei Verner; Thomas J Hudson; Pui-Yan Kwok; Dongmei Cai; Daniel C Koboldt; Raymond D Miller; Ludmila Pawlikowska; Patricia Taillon-Miller; Ming Xiao; Lap-Chee Tsui; William Mak; You Qiang Song; Paul K H Tam; Yusuke Nakamura; Takahisa Kawaguchi; Takuya Kitamoto; Takashi Morizono; Atsushi Nagashima; Yozo Ohnishi; Akihiro Sekine; Toshihiro Tanaka; Tatsuhiko Tsunoda; Panos Deloukas; Christine P Bird; Marcos Delgado; Emmanouil T Dermitzakis; Rhian Gwilliam; Sarah Hunt; Jonathan Morrison; Don Powell; Barbara E Stranger; Pamela Whittaker; David R Bentley; Mark J Daly; Paul I W de Bakker; Jeff Barrett; Yves R Chretien; Julian Maller; Steve McCarroll; Nick Patterson; Itsik Pe'er; Alkes Price; Shaun Purcell; Daniel J Richter; Pardis Sabeti; Richa Saxena; Stephen F Schaffner; Pak C Sham; Patrick Varilly; David Altshuler; Lincoln D Stein; Lalitha Krishnan; Albert Vernon Smith; Marcela K Tello-Ruiz; Gudmundur A Thorisson; Aravinda Chakravarti; Peter E Chen; David J Cutler; Carl S Kashuk; Shin Lin; Gonçalo R Abecasis; Weihua Guan; Yun Li; Heather M Munro; Zhaohui Steve Qin; Daryl J Thomas; Gilean McVean; Adam Auton; Leonardo Bottolo; Niall Cardin; Susana Eyheramendy; Colin Freeman; Jonathan Marchini; Simon Myers; Chris Spencer; Matthew Stephens; Peter Donnelly; Lon R Cardon; Geraldine Clarke; David M Evans; Andrew P Morris; Bruce S Weir; Tatsuhiko Tsunoda; Todd A Johnson; James C Mullikin; Stephen T Sherry; Michael Feolo; Andrew Skol; Houcan Zhang; Changqing Zeng; Hui Zhao; Ichiro Matsuda; Yoshimitsu Fukushima; Darryl R Macer; Eiko Suda; Charles N Rotimi; Clement A Adebamowo; Ike Ajayi; Toyin Aniagwu; Patricia A Marshall; Chibuzor Nkwodimmah; Charmaine D M Royal; Mark F Leppert; Missy Dixon; Andy Peiffer; Renzong Qiu; Alastair Kent; Kazuto Kato; Norio Niikawa; Isaac F Adewole; Bartha M Knoppers; Morris W Foster; Ellen Wright Clayton; Jessica Watkin; Richard A Gibbs; John W Belmont; Donna Muzny; Lynne Nazareth; Erica Sodergren; George M Weinstock; David A Wheeler; Imtaz Yakub; Stacey B Gabriel; Robert C Onofrio; Daniel J Richter; Liuda Ziaugra; Bruce W Birren; Mark J Daly; David Altshuler; Richard K Wilson; Lucinda L Fulton; Jane Rogers; John Burton; Nigel P Carter; Christopher M Clee; Mark Griffiths; Matthew C Jones; Kirsten McLay; Robert W Plumb; Mark T Ross; Sarah K Sims; David L Willey; Zhu Chen; Hua Han; Le Kang; Martin Godbout; John C Wallenburg; Paul L'Archevêque; Guy Bellemare; Koji Saeki; Hongguang Wang; Daochang An; Hongbo Fu; Qing Li; Zhen Wang; Renwu Wang; Arthur L Holden; Lisa D Brooks; Jean E McEwen; Mark S Guyer; Vivian Ota Wang; Jane L Peterson; Michael Shi; Jack Spiegel; Lawrence M Sung; Lynn F Zacharia; Francis S Collins; Karen Kennedy; Ruth Jamieson; John Stewart
Journal:  Nature       Date:  2007-10-18       Impact factor: 49.962

5.  Loci associated with skin pigmentation identified in African populations.

Authors:  Nicholas G Crawford; Derek E Kelly; Matthew E B Hansen; Marcia H Beltrame; Shaohua Fan; Shanna L Bowman; Ethan Jewett; Alessia Ranciaro; Simon Thompson; Yancy Lo; Susanne P Pfeifer; Jeffrey D Jensen; Michael C Campbell; William Beggs; Farhad Hormozdiari; Sununguko Wata Mpoloka; Gaonyadiwe George Mokone; Thomas Nyambo; Dawit Wolde Meskel; Gurja Belay; Jake Haut; Harriet Rothschild; Leonard Zon; Yi Zhou; Michael A Kovacs; Mai Xu; Tongwu Zhang; Kevin Bishop; Jason Sinclair; Cecilia Rivas; Eugene Elliot; Jiyeon Choi; Shengchao A Li; Belynda Hicks; Shawn Burgess; Christian Abnet; Dawn E Watkins-Chow; Elena Oceana; Yun S Song; Eleazar Eskin; Kevin M Brown; Michael S Marks; Stacie K Loftus; William J Pavan; Meredith Yeager; Stephen Chanock; Sarah A Tishkoff
Journal:  Science       Date:  2017-10-12       Impact factor: 47.728

6.  The Encyclopedia of DNA elements (ENCODE): data portal update.

Authors:  Carrie A Davis; Benjamin C Hitz; Cricket A Sloan; Esther T Chan; Jean M Davidson; Idan Gabdank; Jason A Hilton; Kriti Jain; Ulugbek K Baymuradov; Aditi K Narayanan; Kathrina C Onate; Keenan Graham; Stuart R Miyasato; Timothy R Dreszer; J Seth Strattan; Otto Jolanki; Forrest Y Tanaka; J Michael Cherry
Journal:  Nucleic Acids Res       Date:  2018-01-04       Impact factor: 16.971

7.  Polygenic adaptation on height is overestimated due to uncorrected stratification in genome-wide association studies.

Authors:  Mashaal Sohail; Robert M Maier; Benjamin Neale; Iain Mathieson; David Reich; Shamil R Sunyaev; Andrea Ganna; Alex Bloemendal; Alicia R Martin; Michael C Turchin; Charleston Wk Chiang; Joel Hirschhorn; Mark J Daly; Nick Patterson
Journal:  Elife       Date:  2019-03-21       Impact factor: 8.140

8.  Evidence of widespread selection on standing variation in Europe at height-associated SNPs.

Authors:  Michael C Turchin; Charleston W K Chiang; Cameron D Palmer; Sriram Sankararaman; David Reich; Joel N Hirschhorn
Journal:  Nat Genet       Date:  2012-08-19       Impact factor: 38.330

9.  A map of recent positive selection in the human genome.

Authors:  Benjamin F Voight; Sridhar Kudaravalli; Xiaoquan Wen; Jonathan K Pritchard
Journal:  PLoS Biol       Date:  2006-03-07       Impact factor: 8.029

10.  Tread Lightly Interpreting Polygenic Tests of Selection.

Authors:  John Novembre; Nicholas H Barton
Journal:  Genetics       Date:  2018-04       Impact factor: 4.562

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  1 in total

Review 1.  The road ahead in genetics and genomics.

Authors:  Amy L McGuire; Stacey Gabriel; Sarah A Tishkoff; Ambroise Wonkam; Aravinda Chakravarti; Eileen E M Furlong; Barbara Treutlein; Alexander Meissner; Howard Y Chang; Núria López-Bigas; Eran Segal; Jin-Soo Kim
Journal:  Nat Rev Genet       Date:  2020-08-24       Impact factor: 53.242

  1 in total

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