Luca Coppeta1, Luca Di Giampaolo2, Stefano Rizza3, Ottavia Balbi1, Savino Baldi1, Antonio Pietroiusti1, Andrea Magrini1. 1. Italian study group on the metabolic and immunological effects of night shift workDepartment of Occupational Medicine, University of Rome Tor Vergata, Rome, Italy. 2. Department of Occupational Medicine, University of Chieti G. D'Annunzio, Chieti, Italy. 3. Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
Abstract
OBJECTIVES: The night shift workers were reported to have health consequences, ranging from mild, as cluster headache, to severe, as heart attacks and hormonal irregularities. This study is aimed to perform a systematic review and meta-analyze of the association between the night shift work and the thyroid disorders. METHODS: We comprehensively searched eight databases, including PubMed and Google Scholar for the relevant articles. This systematic review and meta-analysis were conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) statement. RESULTS: We finally included six papers involving 4074 participants. Four papers were eligible for meta-analysis involving 1864 night shift workers and 2017 day shift workers. We against found that thyroid stimulating hormone (TSH) is significantly higher in the night shift group compared to the day shift group. CONCLUSIONS: The higher TSH among the night shift workers is attributed to disruption of the circadian rhythm and sleep/wake cycle, with subsequent eating disorders. We proposed that more attention should be paid to the working pattern and the related health consequences.
OBJECTIVES: The night shift workers were reported to have health consequences, ranging from mild, as cluster headache, to severe, as heart attacks and hormonal irregularities. This study is aimed to perform a systematic review and meta-analyze of the association between the night shift work and the thyroid disorders. METHODS: We comprehensively searched eight databases, including PubMed and Google Scholar for the relevant articles. This systematic review and meta-analysis were conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-analysis (PRISMA) statement. RESULTS: We finally included six papers involving 4074 participants. Four papers were eligible for meta-analysis involving 1864 night shift workers and 2017 day shift workers. We against found that thyroid stimulating hormone (TSH) is significantly higher in the night shift group compared to the day shift group. CONCLUSIONS: The higher TSH among the night shift workers is attributed to disruption of the circadian rhythm and sleep/wake cycle, with subsequent eating disorders. We proposed that more attention should be paid to the working pattern and the related health consequences.
Entities:
Keywords:
TSH; night shift; rotating shift; systematic review; thyroid disease
Authors: Gabriela Maria Berinde; Andreea Iulia Socaciu; Mihai Adrian Socaciu; Andreea Cozma; Armand Gabriel Rajnoveanu; Gabriel Emil Petre; Doina Piciu Journal: Diagnostics (Basel) Date: 2022-01-27