Literature DB >> 32578044

Elimination of Dietary Triggers Is Successful in Treating Symptoms of Gastroesophageal Reflux Disease.

Cesare Tosetti1,2, Edoardo Savarino3, Edoardo Benedetto1,4, Rudi De Bastiani1,5.   

Abstract

BACKGROUND: The relationship between aliments and pathophysiological abnormalities leading to gastroesophageal reflux disease (GERD) symptoms elicitation is unclear. Nevertheless, patients often report symptoms after ingestion of specific foods. AIMS: To identify in primary care setting the presence of foods able to trigger GERD symptoms, and evaluate whether a consequent specific food elimination diet may result in clinical improvement.
METHODS: Diagnosis of GERD and quantification of reflux symptoms were done according to GERD-Q questionnaire (positive when > 8). During clinical data collection, patients were asked to report aliments associated with their symptoms. Also, a precompiled list of additional foods was administered to them. Then, patients were requested to eliminate the specific foods identified, and to come back for follow-up visit after 2 weeks when GERD-Q questionnaire and clinical data collection were repeated.
RESULTS: One-hundred GERD (mean GERD-Q score 11.6) patients (54 females, mean age 48.7 years) were enrolled. Eighty-five patients reported at least one triggering food, mostly spicy foods (62%), chocolate (55%), pizza (55%), tomato (52%), and fried foods (52%). At follow-up visit, the diagnosis of GERD was confirmed in only 55 patients, and the mean GERD-Q score decreased to 8.9. Heartburn reporting decreased from 93 to 44% of patients, while regurgitation decreased from 72 to 28%. About half of the patients agreed to continue with only dietary recommendations.
CONCLUSIONS: Most patients with GERD can identify at least one food triggering their symptoms. An approach based on abstention from identified food may be effective in the short term.

Entities:  

Keywords:  Food; Gastroesophageal reflux disease; Heartburn; Primary care; Regurgitation; Symptoms

Year:  2020        PMID: 32578044     DOI: 10.1007/s10620-020-06414-z

Source DB:  PubMed          Journal:  Dig Dis Sci        ISSN: 0163-2116            Impact factor:   3.199


  41 in total

Review 1.  Alternative therapeutic approaches to chronic proton pump inhibitor treatment.

Authors:  Ronnie Fass
Journal:  Clin Gastroenterol Hepatol       Date:  2011-12-16       Impact factor: 11.382

2.  Impairment of chemical clearance and mucosal integrity distinguishes hypersensitive esophagus from functional heartburn.

Authors:  Marzio Frazzoni; Nicola de Bortoli; Leonardo Frazzoni; Manuele Furnari; Irene Martinucci; Salvatore Tolone; Andrea Farioli; Santino Marchi; Lorenzo Fuccio; Vincenzo Savarino; Edoardo Savarino
Journal:  J Gastroenterol       Date:  2016-05-30       Impact factor: 7.527

3.  Overweight is a risk factor for both erosive and non-erosive reflux disease.

Authors:  Edoardo Savarino; Patrizia Zentilin; Elisa Marabotto; Daria Bonfanti; Simona Inferrera; Lorenzo Assandri; Giorgio Sammito; Lorenzo Gemignani; Manuele Furnari; Pietro Dulbecco; Vincenzo Savarino
Journal:  Dig Liver Dis       Date:  2011-09-22       Impact factor: 4.088

Review 4.  Expert consensus document: Advances in the physiological assessment and diagnosis of GERD.

Authors:  Edoardo Savarino; Albert J Bredenoord; Mark Fox; John E Pandolfino; Sabine Roman; C Prakash Gyawali
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2017-09-27       Impact factor: 46.802

5.  Lack of improvement of impaired chemical clearance characterizes PPI-refractory reflux-related heartburn.

Authors:  Marzio Frazzoni; Leonardo Frazzoni; Salvatore Tolone; Nicola De Bortoli; Vincenzo Savarino; Edoardo Savarino
Journal:  Am J Gastroenterol       Date:  2018-04-23       Impact factor: 10.864

6.  Heartburn: community perceptions.

Authors:  T D Bolin; M G Korman; J Hansky; R Stanton
Journal:  J Gastroenterol Hepatol       Date:  2000-01       Impact factor: 4.029

7.  Healthcare seeking in gastro-oesophageal reflux disease: a qualitative study.

Authors:  Roger Jones; Karen Ballard
Journal:  Eur J Gastroenterol Hepatol       Date:  2008-04       Impact factor: 2.566

8.  Correlation between reflux burden, peristaltic function, and mucosal integrity in GERD patients.

Authors:  Mentore Ribolsi; Chandra Prakash Gyawali; Edoardo Savarino; Benjamin Rogers; Arvind Rengarajan; Marco Della Coletta; Matteo Ghisa; Michele Cicala
Journal:  Neurogastroenterol Motil       Date:  2019-10-31       Impact factor: 3.598

Review 9.  Lifestyle Intervention in Gastroesophageal Reflux Disease.

Authors:  Eivind Ness-Jensen; Kristian Hveem; Hashem El-Serag; Jesper Lagergren
Journal:  Clin Gastroenterol Hepatol       Date:  2015-05-06       Impact factor: 11.382

Review 10.  Ineffective esophageal motility: Concepts, future directions, and conclusions from the Stanford 2018 symposium.

Authors:  C Prakash Gyawali; Daniel Sifrim; Dustin A Carlson; Mary Hawn; David A Katzka; John E Pandolfino; Roberto Penagini; Sabine Roman; Edoardo Savarino; Roger Tatum; Michel Vaezi; John O Clarke; George Triadafilopoulos
Journal:  Neurogastroenterol Motil       Date:  2019-04-11       Impact factor: 3.960

View more
  6 in total

1.  The tapestry of reflux syndromes: translating new insight into clinical practice.

Authors:  Peter J Kahrilas; Edoardo Savarino; Foteini Anastasiou; Albert J Bredenoord; Maura Corsetti; Jesper Lagergren; Juan Mendive; Sophie Nelson; Sabine Roman; Frank Zerbib; Pali Hungin
Journal:  Br J Gen Pract       Date:  2021-09-30       Impact factor: 6.302

Review 2.  Fundoplication versus oral proton pump inhibitors for gastroesophageal reflux disease: a systematic review and meta-analysis of randomized clinical trials.

Authors:  Luca Schiliró Tristão; Francisco Tustumi; Guilherme Tavares; Wanderley Marques Bernardo
Journal:  Esophagus       Date:  2021-02-02       Impact factor: 4.230

3.  Reviewing the User-Centered Design Process for a Comprehensive Gastroesophageal Reflux Disease (GERD) App.

Authors:  Min Ji Kim; Sarah Schroeder; Shuan Chan; Kyle Hickerson; Yi-Ching Lee
Journal:  Int J Environ Res Public Health       Date:  2022-01-20       Impact factor: 3.390

Review 4.  Novel Advances in the Evaluation and Treatment of Children With Symptoms of Gastroesophageal Reflux Disease.

Authors:  Rachel Rosen
Journal:  Front Pediatr       Date:  2022-04-01       Impact factor: 3.569

Review 5.  Evidence-Based and Emerging Dietary Approaches to Upper Disorders of Gut-Brain Interaction.

Authors:  Jan Tack; Hans Tornblom; Victoria Tan; Florencia Carbone
Journal:  Am J Gastroenterol       Date:  2022-04-13       Impact factor: 12.045

Review 6.  Review article: rethinking the "ladder" approach to reflux-like symptom management in the era of PPI "resistance" - a multidisciplinary perspective.

Authors:  A Pali S Hungin; Carmelo Scarpignato; Laurie Keefer; Maura Corsetti; Foteini Anastasiou; Jean W M Muris; Juan M Mendive; Peter J Kahrilas
Journal:  Aliment Pharmacol Ther       Date:  2022-04-22       Impact factor: 9.524

  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.