Literature DB >> 3257586

One factor recognizes the liver-specific enhancers in alpha 1-antitrypsin and transthyretin genes.

D R Grayson1, R H Costa, K G Xanthopoulos, J E Darnell.   

Abstract

Four different regulatory sites required for transcriptional stimulation by the enhancers of two unrelated liver-specific genes alpha 1-antitrypsin and transthyretin appear to bind the same nuclear protein that is found mainly in the liver. Such proteins may provide a basis for a coordinated, hepatocyte-specific control of gene transcription.

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Year:  1988        PMID： 3257586     DOI： 10.1126/science.3257586

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  34 in total

1.  Genetic variation of the transthyretin gene in wild-type transthyretin amyloidosis (ATTRwt).

Authors:  Jacquelyn L Sikora; Mark W Logue; Gloria G Chan; Brian H Spencer; Tatiana B Prokaeva; Clinton T Baldwin; David C Seldin; Lawreen H Connors
Journal:  Hum Genet       Date:  2014-11-04       Impact factor: 4.132

2.  Coordinate regulation of two genes encoding gluconeogenic enzymes by the trans-dominant locus Tse-1.

Authors:  J Lem; A C Chin; M J Thayer; R J Leach; R E Fournier
Journal:  Proc Natl Acad Sci U S A       Date:  1988-10       Impact factor: 11.205

3.  Two regulatory domains flank the mouse H19 gene.

Authors:  H Yoo-Warren; V Pachnis; R S Ingram; S M Tilghman
Journal:  Mol Cell Biol       Date:  1988-11       Impact factor: 4.272

4.  Purified hepatocyte nuclear factor 1 interacts with a family of hepatocyte-specific promoters.

Authors:  G Courtois; S Baumhueter; G R Crabtree
Journal:  Proc Natl Acad Sci U S A       Date:  1988-11       Impact factor: 11.205

5.  Multiple hepatic trans-acting factors are required for in vitro transcription of the human alpha-1-antitrypsin gene.

Authors:  Y Li; R F Shen; S Y Tsai; S L Woo
Journal:  Mol Cell Biol       Date:  1988-10       Impact factor: 4.272

6.  A direct role for C/EBP and the AP-I-binding site in gene expression linked to adipocyte differentiation.

Authors:  R Herrera; H S Ro; G S Robinson; K G Xanthopoulos; B M Spiegelman
Journal:  Mol Cell Biol       Date:  1989-12       Impact factor: 4.272

7.  High level activity of the mouse CCAAT/enhancer binding protein (C/EBP alpha) gene promoter involves autoregulation and several ubiquitous transcription factors.

Authors:  C Legraverend; P Antonson; P Flodby; K G Xanthopoulos
Journal:  Nucleic Acids Res       Date:  1993-04-25       Impact factor: 16.971

8.  Identification of a transthyretin enhancer site that selectively binds the hepatocyte nuclear factor-3 beta isoform.

Authors:  U Samadani; X Qian; R H Costa
Journal:  Gene Expr       Date:  1996

9.  Hepatocyte nuclear factor 1 and C/EBP are essential for the activity of the human apolipoprotein B gene second-intron enhancer.

Authors:  A R Brooks; B Levy-Wilson
Journal:  Mol Cell Biol       Date:  1992-03       Impact factor: 4.272

Review 10.  Multifunctional roles of enolase in Alzheimer's disease brain: beyond altered glucose metabolism.

Authors:  D Allan Butterfield; Miranda L Bader Lange
Journal:  J Neurochem       Date:  2009-09-23       Impact factor: 5.372
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