Literature DB >> 32574206

Use of antibacterials in the management of symptoms of acute respiratory tract infections among children under five years in Gulu, northern Uganda: Prevalence and determinants.

Hindum Lanyero1, Jaran Eriksen2,3, Celestino Obua4, Cecilia Stålsby Lundborg2, Sarah Nanzigu1, Agaba Katureebe5, Joan N Kalyango6,7, Moses Ocan1.   

Abstract

Inappropriate use of antibacterials is a major public health challenge as it can promote emergence of resistance, wastage of financial resources, morbidity and mortality. In this study, we determined the prevalence and factors associated with antibacterial use in managing symptoms of acute respiratory tract infections (ARIs) in households in rural communities of Gulu district, northern Uganda. A cross-sectional study was conducted among households selected using multi-stage sampling. Data were collected through interviews with care-givers of children under five years, using a structured interviewer administered questionnaire. Out of the 856 children who had symptoms of ARIs, 515 (60.2%; CI: 54.5%-65.6%) were treated with antibacterials. The most commonly used antibacterials were amoxicillin (55.2%, n = 358), cotrimoxazole (15.4%, n = 100) and metronidazole (11.4%, n = 74). The determinants of antibacterial use included; getting treatment from a health facility (AOR: 1.85, CI: 1.34-2.56, P < 0.001), households located in peri-urban area (AOR: 2.54, CI: 1.34-4.84, P = 0.005), and a child having cough (AOR: 7.02, CI: 4.36-11.31, P < 0.001). The prevalence of antibacterial use among children under five years with symptoms of ARIs is high in communities of Gulu district, northern Uganda. Getting treatment from a health facility, if a household was located in a peri-urban area and having a cough are positive predictors of antibacterial use. There is need for targeted education on appropriate antibacterial use in rural communities and hospital settings where over prescription is most likely especially in treating symptoms of ARIs among children under five years.

Entities:  

Year:  2020        PMID: 32574206     DOI: 10.1371/journal.pone.0235164

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.240


  6 in total

1.  Analysis of risk factors associated with acute respiratory infections among under-five children in Uganda.

Authors:  Yassin Nshimiyimana; Yingchun Zhou
Journal:  BMC Public Health       Date:  2022-06-17       Impact factor: 4.135

2.  Antibacterial prescription and the associated factors among outpatients diagnosed with respiratory tract infections in Mbarara Municipality, Uganda.

Authors:  Timothy Eria Muwanguzi; Tadele Mekuriya Yadesa; Amon Ganafa Agaba
Journal:  BMC Pulm Med       Date:  2021-11-15       Impact factor: 3.317

3.  Non-prescribed antibiotic use for children at community levels in low- and middle-income countries: a systematic review and meta-analysis.

Authors:  Dumessa Edessa; Nega Assefa; Yadeta Dessie; Fekede Asefa; Girmaye Dinsa; Lemessa Oljira
Journal:  J Pharm Policy Pract       Date:  2022-09-30

4.  Patterns and contextual determinants of antibiotic prescribing for febrile under-five outpatients at primary and secondary healthcare facilities in Bugisu, Eastern Uganda.

Authors:  Gbemisola Allwell-Brown; Juliet Sanyu Namugambe; Jacquellyn Nambi Ssanyu; Emily White Johansson; Laith Hussain-Alkhateeb; Susanne Strömdahl; Andreas Mårtensson; Freddy Eric Kitutu
Journal:  JAC Antimicrob Resist       Date:  2022-09-05

5.  Antibiotic use among children under five years with diarrhea in rural communities of Gulu, northern Uganda: a cross-sectional study.

Authors:  Hindum Lanyero; Moses Ocan; Celestino Obua; Cecilia Stålsby Lundborg; Sarah Nanzigu; Agaba Katureebe; Joan N Kalyango; Jaran Eriksen
Journal:  BMC Public Health       Date:  2021-06-29       Impact factor: 3.295

6.  Validity of caregivers' reports on prior use of antibacterials in children under five years presenting to health facilities in Gulu, northern Uganda.

Authors:  Hindum Lanyero; Moses Ocan; Celestino Obua; Cecilia Stålsby Lundborg; Katureebe Agaba; Joan N Kalyango; Jaran Eriksen; Sarah Nanzigu
Journal:  PLoS One       Date:  2021-09-16       Impact factor: 3.240

  6 in total

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