Francesca Bravi1, Yuan-Chin Amy Lee2, Mia Hashibe2, Paolo Boffetta3,4, David I Conway5, Monica Ferraroni1, Carlo La Vecchia1, Valeria Edefonti1. 1. Branch of Medical Statistics, Biometry, and Epidemiology "G. A. Maccacaro", Department of Clinical Sciences and Community Health, Università degli Studi di Milano, Milano, Italy. 2. Division of Public Health, Department of Family and Preventive Medicine, University of Utah School of Medicine, and Huntsman Cancer Institute, Salt Lake City, UT, USA. 3. Stony Brook Cancer Center, Stony Brook University, Stony Brook, NY, USA. 4. Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy. 5. School of Medicine, Dentistry, and Nursing, University of Glasgow, Glasgow, UK.
Abstract
OBJECTIVE: To summarize the latest evidence on head and neck cancer epidemiology from the International Head and Neck Cancer Epidemiology (INHANCE) consortium. SUBJECTS AND METHODS: INHANCE was established in 2004 to elucidate the etiology of head and neck cancer through pooled analyses of individual-level data on a large scale. We summarize results from recent INHANCE-based publications updating our 2015 overview. RESULTS: Seventeen papers were published between 2015 and May 2020. These studies further define the nature of risks associated with tobacco and alcohol, and occupational exposures on head and neck cancer. The beneficial effects on incidence of head and neck cancer were identified for good oral health, endogenous and exogenous hormonal factors, and selected aspects of diet related to fruit and vegetables. INHANCE has begun to develop risk prediction models and to pool follow-up data on their studies, finding that ~30% of cases had cancer recurrence and 9% second primary cancers, with overall- and disease-specific 5-year-survival of 51% and 57%, respectively. CONCLUSIONS: The number and importance of INHANCE scientific findings provides further evidence of the advantages of large-scale internationally collaborative projects and will support the development of prevention strategies.
OBJECTIVE: To summarize the latest evidence on head and neck cancer epidemiology from the International Head and Neck Cancer Epidemiology (INHANCE) consortium. SUBJECTS AND METHODS: INHANCE was established in 2004 to elucidate the etiology of head and neck cancer through pooled analyses of individual-level data on a large scale. We summarize results from recent INHANCE-based publications updating our 2015 overview. RESULTS: Seventeen papers were published between 2015 and May 2020. These studies further define the nature of risks associated with tobacco and alcohol, and occupational exposures on head and neck cancer. The beneficial effects on incidence of head and neck cancer were identified for good oral health, endogenous and exogenous hormonal factors, and selected aspects of diet related to fruit and vegetables. INHANCE has begun to develop risk prediction models and to pool follow-up data on their studies, finding that ~30% of cases had cancer recurrence and 9% second primary cancers, with overall- and disease-specific 5-year-survival of 51% and 57%, respectively. CONCLUSIONS: The number and importance of INHANCE scientific findings provides further evidence of the advantages of large-scale internationally collaborative projects and will support the development of prevention strategies.
Authors: Emanuele Leoncini; Valeria Edefonti; Mia Hashibe; Maria Parpinel; Gabriella Cadoni; Monica Ferraroni; Diego Serraino; Keitaro Matsuo; Andrew F Olshan; Jose P Zevallos; Deborah M Winn; Kirsten Moysich; Zuo-Feng Zhang; Hal Morgenstern; Fabio Levi; Karl Kelsey; Michael McClean; Cristina Bosetti; Stimson Schantz; Guo-Pei Yu; Paolo Boffetta; Yuan-Chin Amy Lee; Shu-Chun Chuang; Adriano Decarli; Carlo La Vecchia; Stefania Boccia Journal: Eur J Epidemiol Date: 2015-05-01 Impact factor: 8.082
Authors: Carlotta Galeone; Alessandra Tavani; Claudio Pelucchi; Federica Turati; Deborah M Winn; Fabio Levi; Guo-Pei Yu; Hal Morgenstern; Karl Kelsey; Luigino Dal Maso; Mark P Purdue; Michael McClean; Renato Talamini; Richard B Hayes; Silvia Franceschi; Stimson Schantz; Zuo-Feng Zhang; Gilles Ferro; Shu-Chun Chuang; Paolo Boffetta; Carlo La Vecchia; Mia Hashibe Journal: Cancer Epidemiol Biomarkers Prev Date: 2010-06-22 Impact factor: 4.254
Authors: Valeria Edefonti; Mia Hashibe; Maria Parpinel; Federica Turati; Diego Serraino; Keitaro Matsuo; Andrew F Olshan; Jose P Zevallos; Deborah M Winn; Kirsten Moysich; Zuo-Feng Zhang; Hal Morgenstern; Fabio Levi; Karl Kelsey; Michael McClean; Cristina Bosetti; Carlotta Galeone; Stimson Schantz; Guo-Pei Yu; Paolo Boffetta; Yuan-Chin Amy Lee; Shu-Chun Chuang; Carlo La Vecchia; Adriano Decarli Journal: Int J Cancer Date: 2015-01-28 Impact factor: 7.396
Authors: Gavin B Stewart; Douglas G Altman; Lisa M Askie; Lelia Duley; Mark C Simmonds; Lesley A Stewart Journal: PLoS One Date: 2012-10-03 Impact factor: 3.240
Authors: V Edefonti; M Hashibe; M Parpinel; M Ferraroni; F Turati; D Serraino; K Matsuo; A F Olshan; J P Zevallos; D M Winn; K Moysich; Z-F Zhang; H Morgenstern; F Levi; K Kelsey; M McClean; C Bosetti; S Schantz; G-P Yu; P Boffetta; S-C Chuang; Y-C A Lee; C La Vecchia; A Decarli Journal: Br J Cancer Date: 2015-05-19 Impact factor: 7.640
Authors: Chun-Pin Chang; Carlo La Vecchia; Diego Serraino; Andrew F Olshan; Jose P Zevallos; Hal Morgenstern; Fabio Levi; Werner Garavello; Karl Kelsey; Michael McClean; Chu Chen; Stephen M Schwartz; Stimson Schantz; Guo-Pei Yu; Paolo Boffetta; Mia Hashibe; Yuan-Chin Amy Lee; Maria Parpinel; Livia S A Augustin; Federica Turati; Zuo-Feng Zhang; Valeria Edefonti Journal: Br J Cancer Date: 2020-01-13 Impact factor: 7.640
Authors: J Ferlay; M Colombet; I Soerjomataram; C Mathers; D M Parkin; M Piñeros; A Znaor; F Bray Journal: Int J Cancer Date: 2018-12-06 Impact factor: 7.396
Authors: Constanza Saka-Herrán; Enric Jané-Salas; Antonio Mano-Azul; Aina Torrejón-Moya; Albert Estrugo-Devesa; José López-López Journal: Pharmaceuticals (Basel) Date: 2022-05-06
Authors: Tobias R Spuldaro; Vivian P Wagner; Felipe Nör; Eduardo J Gaio; Cristiane H Squarize; Vinicius C Carrard; Cassiano K Rösing; Rogerio M Castilho Journal: Int J Oncol Date: 2022-05-06 Impact factor: 5.884
Authors: Tanya Walsh; Richard Macey; Alexander R Kerr; Mark W Lingen; Graham R Ogden; Saman Warnakulasuriya Journal: Cochrane Database Syst Rev Date: 2021-07-20