Literature DB >> 32568926

The Central Role of Osteocytes in the Four Adaptive Pathways of Bone's Mechanostat.

Julie M Hughes1, Colleen M Castellani1, Kristin L Popp, Katelyn I Guerriere1, Ronald W Matheny1, Bradley C Nindl2, Mary L Bouxsein.   

Abstract

We review evidence supporting an updated mechanostat model in bone that highlights the central role of osteocytes within bone's four mechanoadaptive pathways: 1) formation modeling and 2) targeted remodeling, which occur with heightened mechanical loading, 3) resorption modeling, and 4) disuse-mediated remodeling, which occur with disuse. These four pathways regulate whole-bone stiffness in response to changing mechanical demands.

Mesh：

Year:  2020        PMID： 32568926      PMCID： PMC7310270          DOI： 10.1249/JES.0000000000000225

Source DB:  PubMed          Journal:  Exerc Sport Sci Rev        ISSN： 0091-6331            Impact factor:   6.230


  6 in total

1.  Average thickness of the bones of the human neurocranium: development of reference measurements to assist with blunt force trauma interpretations.

Authors:  Samantha K Rowbotham; Calvin G Mole; Diana Tieppo; Magda Blaszkowska; Stephen M Cordner; Soren Blau
Journal:  Int J Legal Med       Date:  2022-04-29       Impact factor: 2.686

Review 2.  Emerging evidence that adaptive bone formation inhibition by non-steroidal anti-inflammatory drugs increases stress fracture risk.

Authors:  Jeffery S Staab; Alexander L Kolb; Ryan E Tomlinson; Paola Divieti Pajevic; Ronald W Matheny; Julie M Hughes
Journal:  Exp Biol Med (Maywood)       Date:  2021-02-27

3.  Osteocyte Apoptosis Contributes to Cold Exposure-induced Bone Loss.

Authors:  Jingke Du; Zihao He; Junqi Cui; Hanjun Li; Mingming Xu; Shuhong Zhang; Shuangyan Zhang; Mengning Yan; Xinhua Qu; Zhifeng Yu
Journal:  Front Bioeng Biotechnol       Date:  2021-11-11

4.  Progressive Resistance Training for Concomitant Increases in Muscle Strength and Bone Mineral Density in Older Adults: A Systematic Review and Meta-Analysis.

Authors:  Steven J O'Bryan; Catherine Giuliano; Mary N Woessner; Sara Vogrin; Cassandra Smith; Gustavo Duque; Itamar Levinger
Journal:  Sports Med       Date:  2022-05-24       Impact factor: 11.928

Review 5.  Effects of different exercise intensity on bone mineral density in adults: a comparative systematic review and meta-analysis.

Authors:  S Kast; M Shojaa; M Kohl; S von Stengel; M Gosch; F Jakob; K Kerschan-Schindl; B Kladny; N Klöckner; U Lange; S Middeldorf; S Peters; D Schoene; C Sieber; F Thomasius; M Uder; W Kemmler
Journal:  Osteoporos Int       Date:  2022-03-18       Impact factor: 5.071

6.  Estrogen depletion on In vivo osteocyte calcium signaling responses to mechanical loading.

Authors:  Karl J Lewis; Pamela Cabahug-Zuckerman; James F Boorman-Padgett; Jelena Basta-Pljakic; Joyce Louie; Samuel Stephen; David C Spray; Mia M Thi; Zeynep Seref-Ferlengez; Robert J Majeska; Sheldon Weinbaum; Mitchell B Schaffler
Journal:  Bone       Date:  2021-06-24       Impact factor: 4.398
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.