Literature DB >> 32550979

Can Drug Repositioning Work as a Systematical Business Model?

Jianan Huang1.   

Abstract

As a business model, drug repositioning is facing increasing challenges from both academia and industry. To examine the feasibility of drug repositioning as a systematical business model, a drug revenue formula is introduced. By breaking down key factors into indication, price, patient population, and market share, the potentiality of the drug repositioing business model is confirmed. In addition, some unworkable repositioning stratgies are also summarized.
Copyright © 2020 American Chemical Society.

Entities:  

Year:  2020        PMID: 32550979      PMCID: PMC7294547          DOI: 10.1021/acsmedchemlett.0c00122

Source DB:  PubMed          Journal:  ACS Med Chem Lett        ISSN: 1948-5875            Impact factor:   4.345


  9 in total

1.  Industry continues dabbling with open innovation models.

Authors:  Cormac Sheridan
Journal:  Nat Biotechnol       Date:  2011-12-08       Impact factor: 54.908

2.  Racializing drug design: implications of pharmacogenomics for health disparities.

Authors:  Sandra Soo-Jin Lee
Journal:  Am J Public Health       Date:  2005-10-27       Impact factor: 9.308

3.  Dimebon in Alzheimer's disease: old drug for new indication.

Authors:  Alistair Burns; Robin Jacoby
Journal:  Lancet       Date:  2008-07-19       Impact factor: 79.321

Review 4.  Accessing external innovation in drug discovery and development.

Authors:  Pierre Tufféry
Journal:  Expert Opin Drug Discov       Date:  2015-04-24       Impact factor: 6.098

Review 5.  Racing to define pharmaceutical R&D external innovation models.

Authors:  Liangsu Wang; Andrew Plump; Michael Ringel
Journal:  Drug Discov Today       Date:  2014-10-30       Impact factor: 7.851

6.  New uses for old drugs.

Authors:  Pan Pantziarka; Munir Pirmohamed; Nasir Mirza
Journal:  BMJ       Date:  2018-06-26

7.  Can you teach old drugs new tricks?

Authors:  Nicola Nosengo
Journal:  Nature       Date:  2016-06-16       Impact factor: 49.962

8.  Encouraging New Uses for Old Drugs.

Authors:  Rachel E Sachs; Paul B Ginsburg; Dana P Goldman
Journal:  JAMA       Date:  2017-12-26       Impact factor: 56.272

9.  Sex and Race Differences in the Association Between Statin Use and the Incidence of Alzheimer Disease.

Authors:  Julie M Zissimopoulos; Douglas Barthold; Roberta Diaz Brinton; Geoffrey Joyce
Journal:  JAMA Neurol       Date:  2017-02-01       Impact factor: 18.302

  9 in total
  1 in total

Review 1.  Local Anesthetic Ropivacaine Exhibits Therapeutic Effects in Cancers.

Authors:  Peng Xu; Shaobo Zhang; Lili Tan; Lei Wang; Zhongwei Yang; Jinbao Li
Journal:  Front Oncol       Date:  2022-02-03       Impact factor: 6.244

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.