Literature DB >> 32547841

Innovative Approaches for Slowing Disease Progression in Parkinson's Disease: Takeaways from the 14th Annual International Society for Central Nervous System Clinical Trials and Methodology Scientific Meeting.

Monica Javidnia1,2,3,4,5, Mark Frasier1,2,3,4,5, Ira Shoulson1,2,3,4,5, Ibrahim Turkoz1,2,3,4,5, Kumar Budur1,2,3,4,5.   

Abstract

The International Society for Central Nervous System Clinical Trials and Methodology (ISCTM) partnered with the Michael J. Fox Foundation for Parkinson's Research to hold a joint session on innovation in Parkinson's disease research at the ISCTM 14th Annual Scientific Meeting held February 20 to 22, 2018 in Washington, D.C. The session focused on (1) biomarkers and outcomes measures in Parkinson's disease clinical trials; 2) clinical trial designs, outcomes, and statistical approaches; and 3) the path forward. This paper aims to summarize key takeaways from the session presenters, panelists, and audience members.
Copyright © 2020. Matrix Medical Communications. All rights reserved.

Entities:  

Keywords:  Parkinson’s disease; RBD; disease modification; disease progression; prodromal

Year:  2020        PMID: 32547841      PMCID: PMC7239563     

Source DB:  PubMed          Journal:  Innov Clin Neurosci        ISSN: 2158-8333


  41 in total

Review 1.  MDS research criteria for prodromal Parkinson's disease.

Authors:  Daniela Berg; Ronald B Postuma; Charles H Adler; Bastiaan R Bloem; Piu Chan; Bruno Dubois; Thomas Gasser; Christopher G Goetz; Glenda Halliday; Lawrence Joseph; Anthony E Lang; Inga Liepelt-Scarfone; Irene Litvan; Kenneth Marek; José Obeso; Wolfgang Oertel; C Warren Olanow; Werner Poewe; Matthew Stern; Günther Deuschl
Journal:  Mov Disord       Date:  2015-10       Impact factor: 10.338

2.  The future is now: model-based clinical trial design for Alzheimer's disease.

Authors:  K Romero; K Ito; J A Rogers; D Polhamus; R Qiu; D Stephenson; R Mohs; R Lalonde; V Sinha; Y Wang; D Brown; M Isaac; S Vamvakas; R Hemmings; L Pani; L J Bain; B Corrigan
Journal:  Clin Pharmacol Ther       Date:  2014-12-27       Impact factor: 6.875

3.  Loss of dorsolateral nigral hyperintensity on 3.0 tesla susceptibility-weighted imaging in idiopathic rapid eye movement sleep behavior disorder.

Authors:  Roberto De Marzi; Klaus Seppi; Birgit Högl; Christoph Müller; Christoph Scherfler; Ambra Stefani; Alex Iranzo; Eduardo Tolosa; Joan Santamarìa; Elke Gizewski; Michael Schocke; Elisabeth Skalla; Christian Kremser; Werner Poewe
Journal:  Ann Neurol       Date:  2016-04-22       Impact factor: 10.422

4.  DATATOP: a multicenter controlled clinical trial in early Parkinson's disease. Parkinson Study Group.

Authors: 
Journal:  Arch Neurol       Date:  1989-10

5.  Skin nerve phosphorylated α-synuclein deposits in idiopathic REM sleep behavior disorder.

Authors:  Elena Antelmi; Vincenzo Donadio; Alex Incensi; Giuseppe Plazzi; Rocco Liguori
Journal:  Neurology       Date:  2017-05-03       Impact factor: 9.910

6.  Impact of the motor complications of Parkinson's disease on the quality of life.

Authors:  Stéphane Chapuis; Lemlih Ouchchane; Olivier Metz; Laurent Gerbaud; Franck Durif
Journal:  Mov Disord       Date:  2005-02       Impact factor: 10.338

7.  Screening for prodromal Parkinson's disease in the general community: a sleep-based approach.

Authors:  Ronald B Postuma; Amelie Pelletier; Daniela Berg; Jean-Francois Gagnon; Frédérique Escudier; Jacques Montplaisir
Journal:  Sleep Med       Date:  2016-03-10       Impact factor: 3.492

Review 8.  Targeted Therapies for Parkinson's Disease: From Genetics to the Clinic.

Authors:  S Pablo Sardi; Jesse M Cedarbaum; Patrik Brundin
Journal:  Mov Disord       Date:  2018-04-27       Impact factor: 10.338

9.  Basal ganglia dysfunction in idiopathic REM sleep behaviour disorder parallels that in early Parkinson's disease.

Authors:  Michal Rolinski; Ludovica Griffanti; Paola Piccini; Andreas A Roussakis; Konrad Szewczyk-Krolikowski; Ricarda A Menke; Timothy Quinnell; Zenobia Zaiwalla; Johannes C Klein; Clare E Mackay; Michele T M Hu
Journal:  Brain       Date:  2016-06-12       Impact factor: 13.501

Review 10.  Clinical diagnostic criteria for dementia associated with Parkinson's disease.

Authors:  Murat Emre; Dag Aarsland; Richard Brown; David J Burn; Charles Duyckaerts; Yoshikino Mizuno; Gerald Anthony Broe; Jeffrey Cummings; Dennis W Dickson; Serge Gauthier; Jennifer Goldman; Christopher Goetz; Amos Korczyn; Andrew Lees; Richard Levy; Irene Litvan; Ian McKeith; Warren Olanow; Werner Poewe; Niall Quinn; Christina Sampaio; Eduardo Tolosa; Bruno Dubois
Journal:  Mov Disord       Date:  2007-09-15       Impact factor: 10.338

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