Literature DB >> 32538568

[Masquelet technique combined with flap transplantation for infectious bone and soft tissue defects of lower leg].

Congpeng Meng1, Shuming Ye1, Juehua Jing1.   

Abstract

OBJECTIVE: To investigate the effectiveness of Masquelet technique combined with flap transplantation in treatment of infectious bone and soft tissue defects of the lower leg.
METHODS: Between January 2013 and January 2017, 35 cases of infectious bone and soft tissue defects of lower leg were treated with Masquelet technique combined with flap transplantation. There were 21 males and 14 females, with an average of 31.5 years (mean, 25-55 years). All patients were tibial fractures caused by trauma and the infections occurred after debridement or internal fixation. The time from injury to admission was 1 to 6 months, with an average of 3.2 months. Defect located at the proximal leg in 11 cases, the middle leg in 11 cases, and the distal leg in 13 cases. The length of tibia defect after debridement ranged from 5.6 to 11.2 cm, with an average of 7.1 cm. The size of soft tissue defect ranged from 14.2 cm×6.9 cm to 17.3 cm×8.7 cm. Bacterial culture of purulent secretion of wound was positive in 18 cases. After debridement, the bone cement was used to fill the bone defect and the flap transplantation was used to repair the wound. The bone cement was taken out at 8 to 12 weeks after the one-stage operation, and the bone defect was repaired with autogenous iliac bone or combined with artificial bone.
RESULTS: Three cases had necrosis at the distal edge of the flap after one-stage operation, and survived after dressing change. The other flaps survived successfully, and the wounds healed by first intention. All incisions healed by first intention after two-stage operation. All patients were followed up 24-32 months, with an average of 27 months. The color of the flap was similar to that of the surrounding normal tissue, and its texture was good. X-ray reexamination showed that all bone defects healed after 6-8 months, with an average of 6.7 months. At 9 months after two-stage operation, according to the revised Edwards tibial fracture evaluation standard, 19 cases were excellent, 14 cases were good, and 2 cases were poor, the excellent and good rate was 94.3%. The American Orthopedic Ankle Association (AOFAS) score was 60-98, with an average of 81.3. And 21 cases were excellent, 11 were good, and 3 were fair, with an excellent and good rate of 91.4%.
CONCLUSION: Masquelet technique combined with flap transplantation is an effective treatment for infectious bone and soft tissue defects of lower leg.

Entities:  

Keywords:  Masquelet technique; bone defect; infection; lower leg; soft tissue defect; wound repair

Mesh:

Year:  2020        PMID: 32538568      PMCID: PMC8171539          DOI: 10.7507/1002-1892.201911025

Source DB:  PubMed          Journal:  Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi        ISSN: 1002-1892


  20 in total

1.  Circular external fixation and cemented PMMA spacers for the treatment of complex tibial fractures and infected nonunions with segmental bone loss.

Authors:  Andries H van Niekerk; Franz F Birkholtz; Phillip de Lange; Kevin Tetsworth; Erik Hohmann
Journal:  J Orthop Surg (Hong Kong)       Date:  2017 May-Aug       Impact factor: 1.118

Review 2.  Use of the induced membrane technique for bone tissue engineering purposes: animal studies.

Authors:  Véronique Viateau; Morad Bensidhoum; Geneviève Guillemin; Hervé Petite; Didier Hannouche; Fani Anagnostou; Philippe Pélissier
Journal:  Orthop Clin North Am       Date:  2010-01       Impact factor: 2.472

Review 3.  Osteomyelitis of the hand.

Authors:  R Pinder; G Barlow
Journal:  J Hand Surg Eur Vol       Date:  2015-10-19

Review 4.  Problems, obstacles, and complications of limb lengthening by the Ilizarov technique.

Authors:  D Paley
Journal:  Clin Orthop Relat Res       Date:  1990-01       Impact factor: 4.176

5.  Clinical rating systems for the ankle-hindfoot, midfoot, hallux, and lesser toes.

Authors:  H B Kitaoka; I J Alexander; R S Adelaar; J A Nunley; M S Myerson; M Sanders
Journal:  Foot Ankle Int       Date:  1994-07       Impact factor: 2.827

Review 6.  Management of bone infections in adults: the surgeon's and microbiologist's perspectives.

Authors:  G Mouzopoulos; N K Kanakaris; G Kontakis; O Obakponovwe; R Townsend; P V Giannoudis
Journal:  Injury       Date:  2011-12       Impact factor: 2.586

7.  Mandibular reconstruction using induced membranes with autologous cancellous bone graft and HA-betaTCP: animal model study and preliminary results in patients.

Authors:  N Zwetyenga; S Catros; A Emparanza; C Deminiere; F Siberchicot; J-C Fricain
Journal:  Int J Oral Maxillofac Surg       Date:  2009-08-21       Impact factor: 2.789

8.  Fabrication, vascularization and osteogenic properties of a novel synthetic biomimetic induced membrane for the treatment of large bone defects.

Authors:  Liling Ren; Yunqing Kang; Christopher Browne; Julius Bishop; Yunzhi Yang
Journal:  Bone       Date:  2014-04-18       Impact factor: 4.398

9.  Clinical outcome of deep wound infection after instrumented posterior spinal fusion: a matched cohort analysis.

Authors:  James M Mok; Tenner J Guillaume; Ufuk Talu; Sigurd H Berven; Vedat Deviren; Markus Kroeber; David S Bradford; Serena S Hu
Journal:  Spine (Phila Pa 1976)       Date:  2009-03-15       Impact factor: 3.468

10.  Salvage of a Below Knee Amputation Utilizing Rotationplasty Principles in a Patient with Chronic Tibial Osteomyelitis.

Authors:  Matthew R Moralle; Nicholas D Stekas; Mark C Reilly; Michael S Sirkin; Mark R Adams
Journal:  J Orthop Case Rep       Date:  2016 Apr-Jun
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.