Literature DB >> 32532911

Haematoma complicating subcutaneous fat necrosis of the newborn: a rare complication following therapeutic hypothermia.

Elhaytham Omar Sanad Elsayed1, Kamran Yusuf2, Frankie O G Fraulin3, Prashanth Murthy2.   

Abstract

A term, large for gestational age male newborn, was admitted to the neonatal intensive care unit with meconium aspiration syndrome and severe hypoxic-ischaemic encephalopathy. The baby was treated with therapeutic hypothermia using a total body cooling blanket. After 48 hours, the baby developed tender, indurated subcutaneous nodules consistent with subcutaneous fat necrosis (SCFN). The lesions started initially over the back but gradually spread to cover both shoulders, upper arms, chest area and both thighs. On day 19 of life, multiple small nodules on the back softened and coalesced to form one sizeable fluctuant swelling over the thoracolumbar area. Over a few hours, the swelling rapidly progressed to a large, tense mass with sloughing of the gangrenous overlying skin. This unusual complication of SCFN required surgical intervention for evacuation and debridement of the haematoma followed by graft repair of the skin defect. © BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  dermatology; materno-fetal medicine; neonatal health; neonatal intensive care; plastic and reconstructive surgery

Mesh:

Year:  2020        PMID: 32532911      PMCID: PMC7295416          DOI: 10.1136/bcr-2020-234360

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  13 in total

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Authors:  A D Burden; B R Krafchik
Journal:  Pediatr Dermatol       Date:  1999 Sep-Oct       Impact factor: 1.588

2.  Strategies for reducing the incidence of skin complications in newborns treated with whole-body hypothermia.

Authors:  Luca Filippi; Serena Catarzi; Letizia Padrini; Patrizio Fiorini; Giancarlo la Marca; Renzo Guerrini; Gian Paolo Donzelli
Journal:  J Matern Fetal Neonatal Med       Date:  2012-05-14

3.  Subcutaneous fat necrosis after moderate therapeutic hypothermia in neonates.

Authors:  Brenda Strohm; Anna Hobson; Peter Brocklehurst; A David Edwards; Denis Azzopardi
Journal:  Pediatrics       Date:  2011-07-04       Impact factor: 7.124

4.  Subcutaneous Fat Necrosis of the Newborn: A 20-Year Retrospective Study.

Authors:  Blanca R Del Pozzo-Magaña; Nhung Ho
Journal:  Pediatr Dermatol       Date:  2016-08-30       Impact factor: 1.588

5.  Subcutaneous Fat Necrosis and Hypercalcemia After Therapeutic Hypothermia in Patients With Hypoxic-ischemic Encephalopathy: A Case Series.

Authors:  Sourabh Verma; Sean M Bailey; Pradeep V Mally; Elena V Wachtel
Journal:  Cureus       Date:  2018-07-30

Review 6.  Cooling for newborns with hypoxic ischaemic encephalopathy.

Authors:  Susan E Jacobs; Marie Berg; Rod Hunt; William O Tarnow-Mordi; Terrie E Inder; Peter G Davis
Journal:  Cochrane Database Syst Rev       Date:  2013-01-31

7.  Subcutaneous fat necrosis of the newborn: a systematic evaluation of risk factors, clinical manifestations, complications and outcome of 16 children.

Authors:  E Mahé; N Girszyn; S Hadj-Rabia; C Bodemer; D Hamel-Teillac; Y De Prost
Journal:  Br J Dermatol       Date:  2007-04       Impact factor: 9.302

8.  Subcutaneous fat necrosis in neonates with hypoxic ischaemic encephalopathy registered in the Swiss National Asphyxia and Cooling Register.

Authors:  Beate Grass; Lisa Weibel; Cornelia Hagmann; Barbara Brotschi
Journal:  BMC Pediatr       Date:  2015-07-09       Impact factor: 2.125

9.  Neonatal hypercalcemia secondary to subcutaneous fat necrosis successfully treated with pamidronate: a case series and literature review.

Authors:  Veronica Mugarab Samedi; Kamran Yusuf; Wendy Yee; Hala Obaid; Essa Hamdan Al Awad
Journal:  AJP Rep       Date:  2014-11-19

10.  Report of 2 Novel Presentations of Subcutaneous Fat Necrosis of the Newborn.

Authors:  Susanna M H Kannenberg; H Francois Jordaan; Willem I Visser; Fatima Ahmed; A Fourie Bezuidenhout
Journal:  Dermatopathology (Basel)       Date:  2019-06-26
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