Literature DB >> 22524246

Strategies for reducing the incidence of skin complications in newborns treated with whole-body hypothermia.

Luca Filippi1, Serena Catarzi, Letizia Padrini, Patrizio Fiorini, Giancarlo la Marca, Renzo Guerrini, Gian Paolo Donzelli.   

Abstract

OBJECTIVE: To present the results of a strategy designed to reduce the incidence of skin complications in newborns with hypoxic-ischemic encephalopathy treated with moderate whole-body hypothermia.
DESIGN: Retrospective study.
SETTING: Neonatal Intensive Care Unit (NICU). PATIENTS: Thirty-nine neonates cooled in the considered period. INTERVENTION: Starting from January 2008, for neonates treated with moderate whole-body hypothermia (33.5 °C), the cooling system was set in "automatic servo-controlled mode (ACM)", where the temperature of the circulating water could vary between 4 °C and 42 °C. Starting from January 2009, cooling blankets were used in another type of automatic mode, the "gradient variable mode (GVM)", where the circulating water was maintained at a specific pre-set gradient towards the patient's body temperature, and a specific nursing protocol (NP) was adopted.
MEASUREMENTS AND MAIN RESULTS: Two of the eleven newborns treated with the "ACM" exhibited skin complications compatible with subcutaneous fat necrosis (SFN). None of the twenty-eight newborns treated with the "GVM" exhibited skin complications. A comparison of the biochemical and hematological data between these two groups revealed that newborns treated after the adopting of a NP and the "GVM" showed lower serum protein C and calcium levels, and higher platelet levels.
CONCLUSIONS: Our data suggest that newborns undergoing therapeutic cooling may benefit from a specific NP and correct cooling unit setting. Should further studies confirm our data, this nursing approach could be easily adopted.

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Year:  2012        PMID: 22524246     DOI: 10.3109/14767058.2012.683898

Source DB:  PubMed          Journal:  J Matern Fetal Neonatal Med        ISSN: 1476-4954


  6 in total

1.  Improving the Timeliness and Safety of Therapeutic Hypothermia for Hypoxic-Ischemic Encephalopathy.

Authors:  Hannah N Smith; Colleen A Hughes Driscoll
Journal:  Pediatr Qual Saf       Date:  2020-05-12

Review 2.  Cooling for newborns with hypoxic ischaemic encephalopathy.

Authors:  Susan E Jacobs; Marie Berg; Rod Hunt; William O Tarnow-Mordi; Terrie E Inder; Peter G Davis
Journal:  Cochrane Database Syst Rev       Date:  2013-01-31

3.  Temperature control during therapeutic hypothermia for newborn encephalopathy using different Blanketrol devices.

Authors:  Abbot R Laptook; Howard Kilbride; Edward Shepherd; Scott A McDonald; Seetha Shankaran; William Truog; Abhik Das; Rosemary D Higgins
Journal:  Ther Hypothermia Temp Manag       Date:  2014-12       Impact factor: 1.286

4.  Haematoma complicating subcutaneous fat necrosis of the newborn: a rare complication following therapeutic hypothermia.

Authors:  Elhaytham Omar Sanad Elsayed; Kamran Yusuf; Frankie O G Fraulin; Prashanth Murthy
Journal:  BMJ Case Rep       Date:  2020-06-11

5.  Subcutaneous fat necrosis in neonates with hypoxic ischaemic encephalopathy registered in the Swiss National Asphyxia and Cooling Register.

Authors:  Beate Grass; Lisa Weibel; Cornelia Hagmann; Barbara Brotschi
Journal:  BMC Pediatr       Date:  2015-07-09       Impact factor: 2.125

6.  Subcutaneous Fat Necrosis and Hypercalcemia with Nephrocalcinosis in Infancy: Case Report and Review of the Literature.

Authors:  Katerina Chrysaidou; Georgios Sargiotis; Vasiliki Karava; Dimitrios Liasis; Victor Gourvas; Vissarios Moutsanas; Athanasios Christoforidis; Stella Stabouli
Journal:  Children (Basel)       Date:  2021-05-09
  6 in total

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