| Literature DB >> 32529177 |
E Griffin1,2, K Kavalidou2, B Bonner3, D O'Hagan3, P Corcoran2.
Abstract
BACKGROUND: Few studies have focused on those who present to hospital with suicidal thoughts (suicidal ideation). The aim of this study was to establish the risk of repeat presentation to hospital following suicidal ideation and to identify factors which were associated with further ideation or subsequent self-harm.Entities:
Year: 2020 PMID: 32529177 PMCID: PMC7280762 DOI: 10.1016/j.eclinm.2020.100378
Source DB: PubMed Journal: EClinicalMedicine ISSN: 2589-5370
Cumulative incidence of repeat presentation to hospital following ideation, 2014–2019.
| Ideation followed by repeat presentation (either reason) | Ideation followed by ideation | Ideation followed by self-harm | |||||
|---|---|---|---|---|---|---|---|
| n | Number repeating | Risk of repeat presentation (95% CI) | Number repeating | Risk of repeat presentation (95% CI) | Number repeating | Risk of repeat presentation (95% CI) | |
| 12 months | 9792 | 1218 | 24·0% (23·0–25·0) | 519 | 14·8% (14·0–15·7) | 699 | 9·8% (9·2–10·6) |
| Five years | 9792 | 2513 | 40·5% (38·8–42·3) | 1512 | 28·9% (26·3–31·7) | 1001 | 18·3% (17·1–19·6) |
Unadjusted and adjusted cox proportional hazard survival analyses for repeat ideation, 2014–2019.
| n | Number of repeat presentations | Unadjusted HR (95% CI) | p-value | Adjusted HR (95% CI) | p-value | |
|---|---|---|---|---|---|---|
| Gender | ||||||
| Male | 9448 | 3350 | 1.26 (1.10–1.44) | 0.001 | 1·16 (1·07–1·25) | <0·001 |
| Female | 5247 | 1553 | [Reference] | [Reference] | ||
| Age | ||||||
| <30yrs | 5867 | 1675 | 0.76 (0.63–0.93) | 0.007 | 0·97 (0·87–1·09) | 0·622 |
| 30–54yrs | 6959 | 2574 | 1.06 (0.86–1.30) | 0.586 | 1·08 (0·95–1·22) | 0·244 |
| 55+yrs | 1869 | 654 | [Reference] | [Reference] | ||
| Alcohol involvement | ||||||
| No | 8282 | 2355 | [Reference] | [Reference] | ||
| Yes | 6413 | 2548 | 1.50 (1.34–1.68) | <0.001 | 1·13 (1·05–1·23) | <0·001 |
| Time of presentation | ||||||
| 9am until 5pm | 4754 | 1362 | [Reference] | [Reference] | ||
| 5pm until 9am | 9941 | 3541 | 1.31 (1.21–1.41) | <0.001 | 1·14 (1·07–1·22) | <0·001 |
| Weekend presentation | ||||||
| Yes | 10 450 | 3522 | 1.04 (0.98–1.12) | 0.213 | ||
| No | 4245 | 1381 | [Reference] | |||
| Mode of arrival | ||||||
| Ambulance | 5355 | 2108 | 1.49 (1.32–1.67) | <0.001 | 1·08 (1·00–1·18) | 0·049 |
| Other emergency services | 2644 | 941 | 1.39 (1.24–1.55) | <0.001 | 1·04 (0·95–1·15) | 0·362 |
| Self-presenting | 6696 | 1854 | [Reference] | [Reference] | ||
| Mental health assessment | ||||||
| Yes/ referred | 12 873 | 4175 | 0.82 (0.74–0.91) | <0.001 | 1.02 (0.93–1.12) | 0·627 |
| No | 1818 | 727 | [Reference] | [Reference] | ||
| Recommended next care | ||||||
| Medical admission | 3695 | 1384 | 1.31 (1.21–1.42) | <0.001 | 1·09 (1·01–1·16) | 0·023 |
| Psychiatric admission | 1233 | 416 | 1.12 (0.99–1.27) | 0.075 | 1·09 (0·97–1·22) | 0·132 |
| Refused admission/ left before recommendation | 1261 | 562 | 1.65 (1.48–1.86) | <0.001 | 1·23 (1·10–1·37) | <0·001 |
| Discharged from ED | 8506 | 2541 | [Reference] | [Reference] | ||
| Number of previous ideation presentations within study period | ||||||
| None | 9792 | 2146 | [Reference] | |||
| One previous | 2146 | 901 | 2·41 (2·23–2·60) | <0·001 | 2·34 (2·16–2·53) | <0·001 |
| Two previous | 901 | 467 | 3·49 (3·16–3·86) | <0·001 | 3·30 (2·98–3·66) | <0·001 |
| Three previous | 467 | 297 | 4·91 (4·35–5·54) | <0·001 | 4·68 (4·14–5·29) | <0·001 |
| Four or more previous | 1389 | 1092 | 9·14 (7·85–10·63) | <0·001 | 8·24 (7·19–9·45) | <0·001 |
Unadjusted and adjusted cox proportional hazard survival analyses for subsequent self-harm, 2014–2019.
| n | Number of repeat presentations | Unadjusted HR (95% CI) | p-value | Adjusted HR (95% CI) | p-value | |
|---|---|---|---|---|---|---|
| Gender | ||||||
| Male | 6391 | 599 | 0.80 (0.71–0.91) | 0.001 | 0·80 (0·71–0·91) | 0·001 |
| Female | 3484 | 402 | [Reference] | [Reference] | ||
| Age | ||||||
| <30yrs | 3890 | 496 | 2.13 (1.69–2.70) | <0.001 | 2·04 (1·61–2·58) | <0·001 |
| 30–54yrs | 4641 | 421 | 1.44 (1.14–1.83) | 0.003 | 1·44 (1·14–1·83) | 0·002 |
| 55+yrs | 1344 | 84 | [Reference] | [Reference] | ||
| Alcohol involved | ||||||
| No | 5823 | 604 | [Reference] | – | ||
| Yes | 4052 | 397 | 0.90 (0.79–1.02) | 0.109 | – | |
| Time of presentation | ||||||
| 9am until 5pm | 3439 | 350 | [Reference] | – | ||
| 5pm until 9am | 6436 | 651 | 0.98 (0.86–1.12) | 0.775 | – | |
| Weekend presentation | ||||||
| Yes | 6978 | 706 | 1.00 (0.88–1.15) | 0.951 | – | |
| No | 2897 | 295 | [Reference] | – | ||
| Mode of arrival | ||||||
| Ambulance | 3425 | 327 | 0.86 (0.75–0.99) | 0.042 | 0.96 (0.83–1.11) | 0.567 |
| Other emergency services | 1537 | 169 | 1.05 (0.88–1.25) | 0.581 | 1.10 (0.93–1.32) | 0.269 |
| Self-presenting | 4913 | 505 | [Reference] | – | ||
| Mental health assessment | ||||||
| Yes/ referred | 8706 | 881 | 1.11 (0.91–1.34) | 0.301 | – | |
| No | 1168 | 120 | [Reference] | – | ||
| Recommended next care | ||||||
| Medical admission | 2457 | 233 | 0.91 (0.78–1.06) | 0.248 | ||
| Psychiatric admission | 807 | 85 | 1.02 (0.81–1.28) | 0.860 | ||
| Refused admission/ left before recommendation | 734 | 85 | 1.11 (0.88–1.39) | 0.389 | ||
| Discharged from ED | 5877 | 598 | [Reference] | |||
| Number of previous ideation presentations within study period | ||||||
| None | 7838 | 835 | [Reference] | [Reference] | ||
| One previous | 1209 | 125 | 1·05 (0·87–1·27) | 0·630 | 1·08 (0·89–1·30) | 0·438 |
| Two previous | 393 | 28 | 0·75 (0·52–1·10) | 0·139 | 0·82 (0·56–1·19) | 0·299 |
| Three previous | 165 | 9 | 0·58 (0·30–1·11) | 0·101 | 0·66 (0·34–1·26) | 0·209 |
| Four or more previous | 270 | 4 | 0·16 (0·57–0·44) | <0·001 | 0·19 (0·07–0·53) | 0.002 |
Data censored once subsequent self-harm presentation made.
Fig. 1Adjusted cox proportional hazard survival analyses for repeat presentation to hospital following ideation, according number of previous ideation presentations within study period. Note: Adjusted for other variables listed in Tables 2 and 3. For risk of self-harm following ideation, data censored once subsequent self-harm presentation made.
Fig. 2Kaplan-Meier failure curves showing, for ideation presentations, the cumulative probability of a repeat presentation with ideation (left) or self-harm (right), according to the number of previous ideation presentations within study period. Numbers at risk at 12-month intervals are tabulated underneath. For risk of subsequent self-harm, data censored once subsequent self-harm presentation made.