Literature DB >> 3251501

Plasma 10-hydroxynortriptyline and therapeutic response in geriatric depression.

R C Young1, G S Alexopoulos, R Shindledecker, A K Dhar, H Kutt.   

Abstract

Geriatric inpatients with major depression received nortriptyline for 4 weeks. Plasma E-10-hydroxynortriptyline concentrations were correlated positively with residual Hamilton depression ratings and negatively with changes in ratings.

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Year:  1988        PMID： 3251501     DOI： 10.1016/0893-133x(88)90019-x

Source DB:  PubMed          Journal:  Neuropsychopharmacology        ISSN： 0893-133X            Impact factor:   7.853


  5 in total

1.  Self-inhibiting action of nortriptyline's anti-immobility effect at high plasma and brain levels in mice.

Authors:  I Reis de Oliveria; B Diquet; V Van der Meersch; R Dardennes; J Gonidec; P A do Prado-Lima
Journal:  Psychopharmacology (Berl)       Date:  1990       Impact factor: 4.530

Review 2.  The Role of Metabolites of Antidepressants in the Treatment of Depression.

Authors:  M V Rudorfer; W Z Potter
Journal:  CNS Drugs       Date:  1997-04       Impact factor: 5.749

Review 3.  Active hydroxymetabolites of antidepressants. Emphasis on E-10-hydroxy-nortriptyline.

Authors:  C Nordin; L Bertilsson
Journal:  Clin Pharmacokinet       Date:  1995-01       Impact factor: 6.447

Review 4.  Metabolism of tricyclic antidepressants.

Authors:  M V Rudorfer; W Z Potter
Journal:  Cell Mol Neurobiol       Date:  1999-06       Impact factor: 5.046

Review 5.  Clinical pharmacokinetic considerations in the elderly. An update.

Authors:  S Dawling; P Crome
Journal:  Clin Pharmacokinet       Date:  1989-10       Impact factor: 6.447
  5 in total

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