Literature DB >> 32512174

New methodologies in ageing research.

Brenna Osborne1, Daniela Bakula1, Michael Ben Ezra1, Charlotte Dresen1, Esben Hartmann1, Stella M Kristensen1, Garik V Mkrtchyan1, Malte H Nielsen1, Michael A Petr1, Morten Scheibye-Knudsen2.   

Abstract

Ageing is arguably the most complex phenotype that occurs in humans. To understand and treat ageing as well as associated diseases, highly specialised technologies are emerging that reveal critical insight into the underlying mechanisms and provide new hope for previously untreated diseases. Herein, we describe the latest developments in cutting edge technologies applied across the field of ageing research. We cover emerging model organisms, high-throughput methodologies and machine-driven approaches. In all, this review will give you a glimpse of what will be pushing the field onwards and upwards.
Copyright © 2020 The Author(s). Published by Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Ageing; High-throughput methods; Machine learning; Model organisms

Mesh:

Year:  2020        PMID: 32512174     DOI: 10.1016/j.arr.2020.101094

Source DB:  PubMed          Journal:  Ageing Res Rev        ISSN: 1568-1637            Impact factor:   10.895


  4 in total

Review 1.  Clinical Trials Targeting Aging.

Authors:  Johannes Leth Nielsen; Daniela Bakula; Morten Scheibye-Knudsen
Journal:  Front Aging       Date:  2022-02-04

Review 2.  ARDD 2020: from aging mechanisms to interventions.

Authors:  Garik V Mkrtchyan; Kotb Abdelmohsen; Pénélope Andreux; Ieva Bagdonaite; Nir Barzilai; Søren Brunak; Filipe Cabreiro; Rafael de Cabo; Judith Campisi; Ana Maria Cuervo; Marco Demaria; Collin Y Ewald; Evandro Fei Fang; Richard Faragher; Luigi Ferrucci; Adam Freund; Carlos G Silva-García; Anastasia Georgievskaya; Vadim N Gladyshev; David J Glass; Vera Gorbunova; Aubrey de Grey; Wei-Wu He; Jan Hoeijmakers; Eva Hoffmann; Steve Horvath; Riekelt H Houtkooper; Majken K Jensen; Martin Borch Jensen; Alice Kane; Moustapha Kassem; Peter de Keizer; Brian Kennedy; Gerard Karsenty; Dudley W Lamming; Kai-Fu Lee; Nanna MacAulay; Polina Mamoshina; Jim Mellon; Marte Molenaars; Alexey Moskalev; Andreas Mund; Laura Niedernhofer; Brenna Osborne; Heidi H Pak; Andrey Parkhitko; Nuno Raimundo; Thomas A Rando; Lene Juel Rasmussen; Carolina Reis; Christian G Riedel; Anais Franco-Romero; Björn Schumacher; David A Sinclair; Yousin Suh; Pam R Taub; Debra Toiber; Jonas T Treebak; Dario Riccardo Valenzano; Eric Verdin; Jan Vijg; Sergey Young; Lei Zhang; Daniela Bakula; Alex Zhavoronkov; Morten Scheibye-Knudsen
Journal:  Aging (Albany NY)       Date:  2020-12-30       Impact factor: 5.682

3.  Bibliometric Analysis on Geriatric Nursing Research in Web of Science (1900-2020).

Authors:  Arezoo Ghamgosar; Maryam Zarghani; Leila Nemati-Anaraki
Journal:  Biomed Res Int       Date:  2021-09-28       Impact factor: 3.411

4.  DeepMAge: A Methylation Aging Clock Developed with Deep Learning.

Authors:  Fedor Galkin; Polina Mamoshina; Kirill Kochetov; Denis Sidorenko; Alex Zhavoronkov
Journal:  Aging Dis       Date:  2021-08-01       Impact factor: 6.745

  4 in total

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