Literature DB >> 32509763

Isolated Ocular Sarcoidosis Mimicking Ring Melanoma.

Carsten Faber1, Rasmus Ejstrup1, Karine Madsen2, Steffen Heegaard1,3, David Scheie3, Jens Folke Kiilgaard1.   

Abstract

We report the case of a 25-year-old female, who presented with a large, pale tumor of her ciliary body that extended to >180° of the anterior chamber angle. All preoperative examinations including ultrasound biomicroscopy, scleral transillumination, and MRI indicated melanoma. A thorough systemic work-up was negative. A diagnosis of ring melanoma was suspected, and the patient was scheduled for enucleation. However, perioperative frozen section indicated granulomatous inflammation. The enucleation was cancelled, and a subtenon injection of triamcinolone was administered, which resulted in the disappearance of the tumor. Together, the findings meet the criteria for the diagnosis of isolated ocular sarcoidosis. This case demonstrates that a sarcoid granuloma can mimic all clinical features of a ring melanoma. Therefore, a biopsy should be done before destructive surgery is carried out.
Copyright © 2019 by S. Karger AG, Basel.

Entities:  

Keywords:  Diagnostics; Inflammation; Ocular sarcoidosis; Transscleral biopsy; Uveal melanoma

Year:  2019        PMID: 32509763      PMCID: PMC7250346          DOI: 10.1159/000504784

Source DB:  PubMed          Journal:  Ocul Oncol Pathol        ISSN: 2296-4657


  6 in total

1.  Ring melanoma of the ciliary body: report on twenty-three patients.

Authors:  Hakan Demirci; Carol L Shields; Jerry A Shields; Santosh G Honavar; Ralph C Eagle
Journal:  Retina       Date:  2002-12       Impact factor: 4.256

2.  Amelanotic Irido-Ciliary Ring Melanoma: A Clinicopathological Correlation.

Authors:  Hassan A Aziz; Yasha S Modi; Thomas P Plesec; Arun D Singh
Journal:  Ocul Oncol Pathol       Date:  2015-12-02

Review 3.  Secondary glaucoma as initial manifestation of ring melanoma: a case report and review of literature.

Authors:  Manli Zhao; Yalin Mu; Yalong Dang; Yu Zhu
Journal:  Int J Clin Exp Pathol       Date:  2014-10-15

4.  Semicircular tumor of the iris and uveitis as unilocal manifestation of sarcoidosis.

Authors:  S M Maca; U Firbas; W Hauff; G Zettinig; R Horvat; T Barisani-Asenbauer
Journal:  Ocul Immunol Inflamm       Date:  2004-09       Impact factor: 3.070

5.  International criteria for the diagnosis of ocular sarcoidosis: results of the first International Workshop On Ocular Sarcoidosis (IWOS).

Authors:  Carl P Herbort; Narsing A Rao; Manabu Mochizuki
Journal:  Ocul Immunol Inflamm       Date:  2009 May-Jun       Impact factor: 3.070

Review 6.  Solitary sarcoid granuloma of the iris mimicking tuberculosis: a case report.

Authors:  Robert Rejdak; Pavel Pogorelov; Christian Y Mardin; Małgorzata Szkaradek; Anselm G M Juenemann
Journal:  J Ophthalmol       Date:  2014-03-10       Impact factor: 1.909

  6 in total

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