Hassan A Aziz1, Yasha S Modi1, Thomas P Plesec2, Arun D Singh1. 1. Department of Ophthalmology, Cole Eye Institute, Cleveland, Ohio, USA. 2. Department of Pathology, Robert J. Tomsich Pathology and Laboratory Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
Abstract
PURPOSE: To report a case of an amelanotic irido-ciliary ring melanoma. DESIGN: Interventional case report. RESULTS: A 44-year-old male was followed for asymptomatic amelanotic iris nevus of the right eye that was noted to have a localized ciliary body mass with ring extension along the trabecular meshwork. Fine needle aspiration biopsy was consistent with malignant melanoma. The patient underwent enucleation and remains disease free at 9 years of follow-up. Histopathology revealed malignant melanoma involving the iris and ciliary body with a 360-degree extension along the trabecular meshwork. The tumor was composed of a mixture of spindled and epithelioid cells with scant pigmentation. CONCLUSIONS: Amelanotic irido-ciliary ring melanoma with growth along the trabecular meshwork is a rare form of uveal melanoma that could present as an inconspicuous amelanotic iris mass.
PURPOSE: To report a case of an amelanotic irido-ciliary ring melanoma. DESIGN: Interventional case report. RESULTS: A 44-year-old male was followed for asymptomatic amelanotic iris nevus of the right eye that was noted to have a localized ciliary body mass with ring extension along the trabecular meshwork. Fine needle aspiration biopsy was consistent with malignant melanoma. The patient underwent enucleation and remains disease free at 9 years of follow-up. Histopathology revealed malignant melanoma involving the iris and ciliary body with a 360-degree extension along the trabecular meshwork. The tumor was composed of a mixture of spindled and epithelioid cells with scant pigmentation. CONCLUSIONS:Amelanotic irido-ciliary ring melanoma with growth along the trabecular meshwork is a rare form of uveal melanoma that could present as an inconspicuous amelanotic iris mass.
Entities:
Keywords:
Amelanotic irido-ciliary ring melanoma; Iris; Melanoma
Authors: Khaled Ali Baniyaseen; Muhammad Saeed; Ahmed Omar Albonni; Bothaina Mohammed Abdulshakour; Ghida Dairi; Faisal A Al-Allaf; Mohiuddin M Taher Journal: Middle East J Dig Dis Date: 2019-05-22