Literature DB >> 3250925

Neonatal screening for congenital adrenal hyperplasia using 17-hydroxyprogesterone assay in filter paper blood spots.

A Larsson1, L Hagenfeldt, U von Döbeln, T Curstedt, J Gustafsson, E Svensson.   

Abstract

Screening of infants for congenital adrenal hyperplasia (CAH) using filter paper blood samples collected on the 5th day of life was performed with a radioimmunoassay for 17-hydroxyprogesterone without extraction with organic solvents. A total of 153,000 newborns were screened and 12 cases of CAH were detected (1:12,800). With recall levels related to gestational age, the recall rate could be lowered to 0.05%.

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Year:  1988        PMID: 3250925     DOI: 10.1159/000181069

Source DB:  PubMed          Journal:  Horm Res        ISSN: 0301-0163


  3 in total

1.  Effect of gender, birth weight and gestational age on serum 17-hydroxyprogesterone concentration and distribution among neonates in Saudi Arabia.

Authors:  A R al-Nuaim; M A Abdullah; B Stevens; M Zain
Journal:  Indian J Pediatr       Date:  1995 Sep-Oct       Impact factor: 1.967

2.  Longitudinal measurements of 17alpha-hydroxyprogesterone in premature infants during the first three months of life.

Authors:  N Linder; N Davidovitch; A Kogan; A Barzilai; J Kuint; R Mazkeret; J Sack
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  1999-11       Impact factor: 5.747

3.  15 beta-hydroxylated steroids may be diagnostically misleading in confirming congenital adrenal hyperplasia suspected by a newborn screening programme.

Authors:  K Lange-Kubini; M Zachmann; B Kempken; T Torresani
Journal:  Eur J Pediatr       Date:  1996-11       Impact factor: 3.183

  3 in total

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