| Literature DB >> 32497017 |
Laura DeLuca1, Tatiana Toro-Ramos2, Andreas Michaelides2, Elizabeth Seng1, Charles Swencionis1.
Abstract
BACKGROUND: The prevalence of obesity and diabetes among middle-aged and older adults is on the rise, and with an increase in the world population of adults aged 60 years and older, the demand for health interventions across age groups is growing. Noom is an mHealth behavior change lifestyle intervention that provides users with tracking features for food and exercise logging and weighing-in as well as access to a virtual 1:1 behavior change coach, support group, and daily curriculum that includes diet-, exercise-, and psychology-based content. Limited research has observed the effect of age on a mobile health (mHealth) lifestyle intervention.Entities:
Keywords: DPP; engagement; lifestyle intervention; mHealth; older adults; weight loss
Year: 2020 PMID: 32497017 PMCID: PMC7303833 DOI: 10.2196/18363
Source DB: PubMed Journal: JMIR Diabetes ISSN: 2371-4379
Figure 1Description of data exclusion and inclusion of those who met study criteria.
Descriptive statistics at baseline for participants of the Healthy Weight and Diabetes Prevention Program curricula.
| Variable | HWa curriculum (n=12,378) | DPPa curriculum (n=2389) | ||
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| .60 | |
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| Male | 1451 (11.7) | 289 (12.1) | — |
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| Female | 10,927 (88.3) | 2100 (87.9) | — |
| Age in years, median (IQR) | 42.0 (38.0-47.0) | 51.0 (44.0-58.0) | <.001 | |
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| <.001 | |
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| Never engaged | 9662 (78.1) | 1480 (62.0) | — |
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| Engaged | 372 (3.0) | 60 (2.5) | — |
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| Starters | 1767 (14.3) | 458 (19.2) | — |
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| Completers | 577 (4.7) | 391 (16.4) | — |
| Initial weight (kg), mean (SD) | 94.1 (20.4) | 94.4 (20.5) | .53 | |
| Height (cm), mean (SD) | 165.9 (7.1) | 167.2 (9.5) | <.001 | |
| Baseline BMI (kg/m2), median (IQR) | 32.6 (29.0-37.6) | 32.2 (29.0-37.0) | .01 | |
aHW: Healthy Weight program.
aDPP: Diabetes Prevention Program.
Descriptive statistics of engagement variables from baseline to weeks 16 and 52.
| Engagement measures | HWa,b curriculum (n=2806), median, (IQR) | DPPb,c curriculum (n=665), median (IQR) | |||
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| Week 16 | 88.0 (3.0-57.0) | 195.0 (6.0-184.8) | ||
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| Week 52 | 91.0 (3.0-58.0) | 218.0 (6.0-202.3) | ||
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| Week 16 | 4.0 (0.3-2.4) | 7.2 (0.4-6.0) | ||
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| Week 52 | 4.1 (0.3-2.4) | 8.2 (0.4-6.7) | ||
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| Week 16 | 26.0 (2.0-16.0) | 29.0 (3.0-28.0) | ||
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| Week 52 | 26.5 (2.0-16.0) | 35.0 (3.0-34.0) | ||
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| Week 16 | 228,923.0 (13,284.0-182,434.0) | 331,572.0 (25,837.0-329,239.0) | ||
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| Week 52 | 267,270.5 (14,082.0-205,220.3) | 629,241.0 (28,654.5-563,706.0) | ||
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| Week 16 | 10.0 (1.0-11.0) | 20.0 (4.0-27.0) | ||
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| Week 52 | 10.0 (1.0-11.0) | 31.0 (4.0-47.0) | ||
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| Week 16 | 13.0 (2.0-22.0) | 25.0 (3.0-46.0) | ||
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| Week 52 | 13.0 (2.0-24.0) | 33.0 (4.0-62.0) | ||
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| Week 16 | 227.5 (30.0-471.9) | 735.0 (60.0-1332.5) | ||
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| Week 52 | 240.0 (30.0-490.0) | 886.0 (60.0-1775.0) | ||
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| Week 16 | 9.0 (2.0-16.0) | 11.0 (2.0-22.0) | ||
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| Week 52 | 9.0 (2.0-16.0) | 13.0 (2.0-25.0) | ||
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| Week 16 | 5.0 (1.0-4.0) | 9.0 (1.0-9.0) | ||
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| Week 52 | 5.0 (1.0-4.0) | 9.0 (1.0-10.0) | ||
aHW: Healthy Weight program.
bFor participants who had engagement data available.
cDPP: Diabetes Prevention Program.
Mixed model evaluating changes in weight by time and curriculum.
| Effect | Estimatea | Standard error | |
| Intercept | 94.09 | 0.18 | <.001 |
| DPPb | 0.29 | 0.46 | 0.53 |
| HWc | N/Ad | N/A | N/A |
| Baseline | N/A | N/A | N/A |
| Week 16 | –3.42 | 0.26 | <.001 |
| Week 52 | –4.55 | 0.76 | <.001 |
| DPP*baselinee | N/A | N/A | N/A |
| DPP*week 16 | –3.20 | 0.42 | <.001 |
| DPP*week 52 | –2.38 | 0.91 | 0.01 |
aEstimate represents predicted value of weight.
bDPP: Diabetes Prevention Program.
cHW: Healthy Weight Program.
dN/A: Reference group used.
e*=interaction.
Mixed model evaluating changes in weight by age, engagement, and time.
| Effect | Estimatea | Standard error | |
| Intercept | 93.68 | 1.12 | <.001 |
| Age | 0.02 | 0.02 | .40 |
| Baseline | N/Ab | N/A | N/A |
| Week 16 | 1.79 | 1.31 | .17 |
| Week 52 | –1.85 | 3.03 | .54 |
| Engagement | –1.33 | 0.39 | <.001 |
| Baseline*agec | N/A | N/A | N/A |
| Week 16*age | –0.12 | 0.03 | <.001 |
| Week 52*age | –0.02 | 0.06 | .67 |
| Age*engagement | 0.02 | 0.01 | .01 |
| Baseline*engagement | N/A | N/A | N/A |
| Week 16*engagement | –0.13 | 0.07 | .06 |
| Week 52*engagement | –0.44 | 0.15 | .004 |
aEstimate represents predicted value of weight.
bN/A: Reference group used.
c*=interaction.
Mixed model evaluating changes in weight by age and time.
| Effect | Estimatea | Standard error | |
| Intercept | 91.95 | 0.97 | <.001 |
| Age | 0.05 | 0.02 | .02 |
| Baseline | N/Ab | N/A | N/A |
| Week 16 | 0.5 | 1.24 | .69 |
| Week 52 | –5.99 | 2.76 | .03 |
| Age*baselinec | N/A | N/A | N/A |
| Age*week 16 | –0.11 | 0.03 | <.001 |
| Age*week 52 | 0.003 | 0.06 | .96 |
aEstimate represents predicted value of weight.
bN/A: Reference group used.
c*=interaction.
Figure 2Interaction between age and time on predicted weight outcomes. Error bars: 95% CI. Data not distinguished by curriculum.
Figure 3Interaction between time and engagement on predicted weight outcomes. Error bars: 95% CI. Data not distinguished by curriculum.