Literature DB >> 32494027

Organoid systems to study the human female reproductive tract and pregnancy.

Lama Alzamil1, Konstantina Nikolakopoulou1, Margherita Y Turco2,3.   

Abstract

Both the proper functioning of the female reproductive tract (FRT) and normal placental development are essential for women's health, wellbeing, and pregnancy outcome. The study of the FRT in humans has been challenging due to limitations in the in vitro and in vivo tools available. Recent developments in 3D organoid technology that model the different regions of the FRT include organoids of the ovaries, fallopian tubes, endometrium and cervix, as well as placental trophoblast. These models are opening up new avenues to investigate the normal biology and pathology of the FRT. In this review, we discuss the advances, potential, and limitations of organoid cultures of the human FRT.

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Mesh：

Year:  2020        PMID： 32494027      PMCID： PMC7852529          DOI： 10.1038/s41418-020-0565-5

Source DB:  PubMed          Journal:  Cell Death Differ        ISSN： 1350-9047            Impact factor:   15.828


  131 in total

1.  A well-defined in vitro three-dimensional culture of human endometrium and its applicability to endometrial cancer invasion.

Authors:  Dong Wook Park; Dong Soon Choi; Hee-Sug Ryu; Hyuck Chan Kwon; Hyun Joo; Churl K Min
Journal:  Cancer Lett       Date:  2003-06-10       Impact factor: 8.679

2.  LONG-TERM CULTIVATION OF HYPODIPLOID HUMAN TUMOR CELLS.

Authors:  N AUERSPERG
Journal:  J Natl Cancer Inst       Date:  1964-01       Impact factor: 13.506

3.  Development of organoids from mouse and human endometrium showing endometrial epithelium physiology and long-term expandability.

Authors:  Matteo Boretto; Benoit Cox; Manuel Noben; Nikolai Hendriks; Amelie Fassbender; Heleen Roose; Frédéric Amant; Dirk Timmerman; Carla Tomassetti; Arne Vanhie; Christel Meuleman; Marc Ferrante; Hugo Vankelecom
Journal:  Development       Date:  2017-04-25       Impact factor: 6.868

Review 4.  Single-cell genomics to guide human stem cell and tissue engineering.

Authors:  J Gray Camp; Damian Wollny; Barbara Treutlein
Journal:  Nat Methods       Date:  2018-08-31       Impact factor: 28.547

Review 5.  Development of the human female reproductive tract.

Authors:  Gerald R Cunha; Stanley J Robboy; Takeshi Kurita; Dylan Isaacson; Joel Shen; Mei Cao; Laurence S Baskin
Journal:  Differentiation       Date:  2018-09-06       Impact factor: 3.880

6.  In-vitro construction of endometrial-like epithelium using CD146+ mesenchymal cells derived from human endometrium.

Authors:  Mehri Fayazi; Mojdeh Salehnia; Saeideh Ziaei
Journal:  Reprod Biomed Online       Date:  2017-06-15       Impact factor: 3.828

7.  N-cadherin identifies human endometrial epithelial progenitor cells by in vitro stem cell assays.

Authors:  Hong P T Nguyen; L Xiao; James A Deane; Ker-Sin Tan; Fiona L Cousins; Hirotaka Masuda; Carl N Sprung; Anna Rosamilia; Caroline E Gargett
Journal:  Hum Reprod       Date:  2017-11-01       Impact factor: 6.918

8.  Patient-derived organoids from endometrial disease capture clinical heterogeneity and are amenable to drug screening.

Authors:  Matteo Boretto; Nina Maenhoudt; Xinlong Luo; Aurélie Hennes; Bram Boeckx; Bich Bui; Ruben Heremans; Lisa Perneel; Hiroto Kobayashi; Indra Van Zundert; Hilde Brems; Benoit Cox; Marc Ferrante; Hiroshi Uji-I; Kian Peng Koh; Thomas D'Hooghe; Arne Vanhie; Ignace Vergote; Christel Meuleman; Carla Tomassetti; Diether Lambrechts; Joris Vriens; Dirk Timmerman; Hugo Vankelecom
Journal:  Nat Cell Biol       Date:  2019-08-01       Impact factor: 28.824

9.  Cytokeratin 17 and p63 are markers of the HPV target cell, the cervical stem cell.

Authors:  Jolise E Martens; Janwillem Arends; Paul J Q Van der Linden; Bert A G De Boer; Theo J M Helmerhorst
Journal:  Anticancer Res       Date:  2004 Mar-Apr       Impact factor: 2.480

10.  Susceptibility of epithelial cells cultured from different regions of human cervix to HPV16-induced immortalization.

Authors:  Han Deng; Eric Hillpot; Philomina Yeboah; Sumona Mondal; Craig D Woodworth
Journal:  PLoS One       Date:  2018-06-26       Impact factor: 3.240
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  20 in total

Review 1.  Strategies for modelling endometrial diseases.

Authors:  Alina R Murphy; Hannes Campo; J Julie Kim
Journal:  Nat Rev Endocrinol       Date:  2022-09-01       Impact factor: 47.564

Review 2.  Bioengineering Approaches for Placental Research.

Authors:  Mackenzie L Wheeler; Michelle L Oyen
Journal:  Ann Biomed Eng       Date:  2021-01-08       Impact factor: 3.934

3.  Collagen I triggers directional migration, invasion and matrix remodeling of stroma cells in a 3D spheroid model of endometriosis.

Authors:  Anna Stejskalová; Victoria Fincke; Melissa Nowak; Yvonne Schmidt; Katrin Borrmann; Marie-Kristin von Wahlde; Sebastian D Schäfer; Ludwig Kiesel; Burkhard Greve; Martin Götte
Journal:  Sci Rep       Date:  2021-02-18       Impact factor: 4.379

Review 4.  Investigation of infertility using endometrial organoids.

Authors:  Konstantina Nikolakopoulou; Margherita Y Turco
Journal:  Reproduction       Date:  2021-05       Impact factor: 3.906

Review 5.  Mechanobiology of the female reproductive system.

Authors:  Sachiko Matsuzaki
Journal:  Reprod Med Biol       Date:  2021-07-31

Review 6.  The Role of BMP Signaling in Female Reproductive System Development and Function.

Authors:  Esmeralda Magro-Lopez; María Ángeles Muñoz-Fernández
Journal:  Int J Mol Sci       Date:  2021-11-03       Impact factor: 5.923

Review 7.  The incompletely fulfilled promise of embryo transfer in cattle-why aren't pregnancy rates greater and what can we do about it?

Authors:  Peter J Hansen
Journal:  J Anim Sci       Date:  2020-11-01       Impact factor: 3.159

Review 8.  Two-Way Development of the Genetic Model for Endometrial Tumorigenesis in Mice: Current and Future Perspectives.

Authors:  Yoshiaki Maru; Yoshitaka Hippo
Journal:  Front Genet       Date:  2021-12-09       Impact factor: 4.599

Review 9.  Studying Müllerian duct anomalies - from cataloguing phenotypes to discovering causation.

Authors:  Laura Santana González; Mara Artibani; Ahmed Ashour Ahmed
Journal:  Dis Model Mech       Date:  2021-06-23       Impact factor: 5.758

Review 10.  Building a stem cell-based primate uterus.

Authors:  Sophie Bergmann; Magdalena Schindler; Clara Munger; Christopher A Penfold; Thorsten E Boroviak
Journal:  Commun Biol       Date:  2021-06-17
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