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Literature DB >> 324867

Bipartite structure of the ade3 locus of Saccharomyces cerevisiae.

Abstract

Forty ade3 mutants were examined with respect to their growth requirements, levels of the tetrahydrofolate interconversion enzymes, and/or map positions. Four deletions were detected. Mutations that result in a requirement for adenine and histidine map in one region of the locus; those which result in a requirement for adenine only map in a quite separate region of the locus, a region not disclosed in previous studies. No correlation was observed between growth properties of the strains and enzyme levels.

Entities: Chemical Gene Species

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Year: 1977 PMID： 324867 PMCID： PMC1213626

Source DB: PubMed Journal: Genetics ISSN： 0016-6731 Impact factor: 4.562

2 in total

1. A deletion map of cyc1 mutants and its correspondence to mutationally altered iso-1-cytochromes c of yeast.

Authors: F Sherman; M Jackson; S W Liebman; A M Schweingruber; J W Stewart
Journal: Genetics Date: 1975-09 Impact factor: 4.562

2. New mutant types at the ade3 locus of Saccharomyces cerevisiae.

Authors: C A Lomax; T S Gross; R A Woods
Journal: J Bacteriol Date: 1971-07 Impact factor: 3.490

2 in total

10 in total

1. Molecular genetic analysis of Saccharomyces cerevisiae C1-tetrahydrofolate synthase mutants reveals a noncatalytic function of the ADE3 gene product and an additional folate-dependent enzyme.

Authors: C K Barlowe; D R Appling
Journal: Mol Cell Biol Date: 1990-11 Impact factor: 4.272

6. Cloning and expression in Escherichia coli of the gene for 10-formyltetrahydrofolate synthetase from Clostridium acidiurici ("Clostridium acidi-urici").

Authors: T R Whitehead; J C Rabinowitz
Journal: J Bacteriol Date: 1986-07 Impact factor: 3.490

10. Nucleotide sequence of the Clostridium acidiurici ("Clostridium acidi-urici") gene for 10-formyltetrahydrofolate synthetase shows extensive amino acid homology with the trifunctional enzyme C1-tetrahydrofolate synthase from Saccharomyces cerevisiae.

Authors: T R Whitehead; J C Rabinowitz
Journal: J Bacteriol Date: 1988-07 Impact factor: 3.490

10 in total

Bipartite structure of the ade3 locus of Saccharomyces cerevisiae.

1. A deletion map of cyc1 mutants and its correspondence to mutationally altered iso-1-cytochromes c of yeast.

2. New mutant types at the ade3 locus of Saccharomyces cerevisiae.

1. Molecular genetic analysis of Saccharomyces cerevisiae C1-tetrahydrofolate synthase mutants reveals a noncatalytic function of the ADE3 gene product and an additional folate-dependent enzyme.

2. Sister chromatids are preferred over homologs as substrates for recombinational repair in Saccharomyces cerevisiae.

3. Mutations in ADE3 reduce the efficiency of the omnipotent suppressor sup45-2.

4. Genetic and biochemical characterization of the galactose gene cluster in Kluyveromyces lactis.

5. The secretory pathway mediates localization of the cell polarity regulator Aip3p/Bud6p.

6. Cloning and expression in Escherichia coli of the gene for 10-formyltetrahydrofolate synthetase from Clostridium acidiurici ("Clostridium acidi-urici").

7. In vivo analysis of folate coenzymes and their compartmentation in Saccharomyces cerevisiae.

8. Function of yeast cytoplasmic C1-tetrahydrofolate synthase.

9. Dominant defects in Drosophila eye pigmentation resulting from a euchromatin-heterochromatin fusion gene.

10. Nucleotide sequence of the Clostridium acidiurici ("Clostridium acidi-urici") gene for 10-formyltetrahydrofolate synthetase shows extensive amino acid homology with the trifunctional enzyme C1-tetrahydrofolate synthase from Saccharomyces cerevisiae.