Literature DB >> 3248386

Mapping studies and expression of genes located on human chromosome 11, band q23.

P D Savage1, C Jones, J Silver, A H Geurts van Kessel, R Gonzalez-Sarmiento, L Palm, C A Hanson, J H Kersey.   

Abstract

Chromosome translocations and deletions may alter cellular proto-oncogenes and result in cellular changes that are important in the pathogenesis of malignancy. The region 11q23 is frequently involved in human malignancy. Utilizing a leukemic cell line with a reciprocal translocation involving 11q23 and somatic cell hybrids derived from this cell line, we analyzed five genes assigned to 11q23: NCAM, CD3D, CD3E, THY1, and ETS1. Our data showed no evidence of direct involvement of these genes in this leukemia but enabled a partial genetic map of this important region of the human genome to be constructed: 11cen--NCAM--CD3([G, D], E)--parallel--(ETS1, THY1)--11qter.

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Year:  1988        PMID： 3248386     DOI： 10.1159/000132680

Source DB:  PubMed          Journal:  Cytogenet Cell Genet        ISSN： 0301-0171


  8 in total

Review 1.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M R Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

2.  Mapping chromosome band 11q23 in human acute leukemia with biotinylated probes: identification of 11q23 translocation breakpoints with a yeast artificial chromosome.

Authors:  J D Rowley; M O Diaz; R Espinosa; Y D Patel; E van Melle; S Ziemin; P Taillon-Miller; P Lichter; G A Evans; J H Kersey
Journal:  Proc Natl Acad Sci U S A       Date:  1990-12       Impact factor: 11.205

3.  Identification of a gene, MLL, that spans the breakpoint in 11q23 translocations associated with human leukemias.

Authors:  S Ziemin-van der Poel; N R McCabe; H J Gill; R Espinosa; Y Patel; A Harden; P Rubinelli; S D Smith; M M LeBeau; J D Rowley
Journal:  Proc Natl Acad Sci U S A       Date:  1991-12-01       Impact factor: 11.205

Review 4.  Comparative map for mice and humans.

Authors:  J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M Kosowsky; T H Roderick
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

5.  Genetic mapping of mouse T3d and T3e between Apoa1 and Ncam.

Authors:  R D Miller; J H Ozaki; R J Riblet; D P Gold
Journal:  Immunogenetics       Date:  1989       Impact factor: 2.846

6.  Analysis of the murine All-1 gene reveals conserved domains with human ALL-1 and identifies a motif shared with DNA methyltransferases.

Authors:  Q Ma; H Alder; K K Nelson; D Chatterjee; Y Gu; T Nakamura; E Canaani; C M Croce; L D Siracusa; A M Buchberg
Journal:  Proc Natl Acad Sci U S A       Date:  1993-07-01       Impact factor: 11.205

7.  Identification and mapping of a common proviral integration site Fli-1 in erythroleukemia cells induced by Friend murine leukemia virus.

Authors:  Y Ben-David; E B Giddens; A Bernstein
Journal:  Proc Natl Acad Sci U S A       Date:  1990-02       Impact factor: 11.205

8.  Analysis of 7 polymorphic markers at chromosome 11q22-23 in 35 ataxia telangiectasia families; further evidence of linkage.

Authors:  C M McConville; C G Woods; M Farrall; J A Metcalfe; A M Taylor
Journal:  Hum Genet       Date:  1990-07       Impact factor: 4.132
  8 in total

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