Literature DB >> 32476714

Endothelial corneal transplants: indications, clinical profile and surgical outcomes in a tertiary care hospital.

Vijay Kumar Sharma1, Santosh Kumar2, Sagarika Patyal3, Hemant S Trehan4, Arun Kumar Yadav5, K Raji6, Anirudh Singh7.   

Abstract

BACKGROUND: Endothelial keratoplasties have become the surgical procedure of choice over full thickness penetrating keratoplasty for corneal decompensation because of endothelial dysfunction.
METHODS: A retrospective data review was performed from February 2016 to April 2017 for all the patients who underwent endothelial keratoplasty in a tertiary care center for Indian Armed Forces.
RESULTS: A total of 161 corneal transplants were performed; endothelial keratoplasties accounted for 34 (21.1%) transplants. Most common indication was pseudophakic/aphakic bullous keratopathy followed by Ahmed glaucoma valve-related corneal decompensation and Fuchs' corneal dystrophy, respectively. Mean preoperative corneal thickness was 845.96 ± 106.9 microns. Mean lenticule thickness was 131.55 ± 42.47 microns with microkeratome for descemet stripping automated endothelial keratoplasty (DSAEK) and 174 ± 70.4 microns manually for descemet stripping endothelial keratoplasty (DSEK). Mean preoperative best-corrected visual acuity (BCVA) was 1.65 LogMAR (Snellen equivalent in meters 2/60 approx) which significantly improved to 0.82 LogMAR (Snellen equivalent in meters 6/36 approx) after surgery. In the DSAEK group, BCVA improved from 1.61 to 0.7 LogMAR, whereas in the DSEK group, the visual acuity improved from 1.7 to 0.94 LogMAR at one-month postoperative period. Postoperatively, two patients had graft detachment and had to undergo repeat DSAEK.
CONCLUSION: Study results suggest the similar trends in our tertiary care hospital as in other most advanced ophthalmic centers around the world for adoption of newer techniques of lamellar corneal transplants and their outcomes.
© 2019 Director General, Armed Forces Medical Services. Published by Elsevier, a division of RELX India Pvt. Ltd.

Entities:  

Keywords:  Ahmed glaucoma valve; Corneal decompensation; Endothelial keratoplasty; Lamellar keratoplasty; Microkeratome

Year:  2019        PMID: 32476714      PMCID: PMC7244876          DOI: 10.1016/j.mjafi.2018.11.010

Source DB:  PubMed          Journal:  Med J Armed Forces India        ISSN: 0377-1237


  22 in total

Review 1.  Endothelial keratoplasty: a revolution in evolution.

Authors:  Arundhati Anshu; Marianne O Price; Donald T H Tan; Francis W Price
Journal:  Surv Ophthalmol       Date:  2012 May-Jun       Impact factor: 6.048

2.  Long-term results of Descemet stripping automated endothelial keratoplasty.

Authors:  Arlene Ratanasit; Mark S Gorovoy
Journal:  Cornea       Date:  2011-12       Impact factor: 2.651

3.  Evolving indications for and trends in keratoplasty in British Columbia, Canada, from 2002 to 2011: a 10-year review.

Authors:  Johnson C H Tan; Simon P Holland; Paul J Dubord; Gregory Moloney; Martin McCarthy; Sonia N Yeung
Journal:  Cornea       Date:  2014-03       Impact factor: 2.651

4.  Descemet's stripping with endothelial keratoplasty: comparative outcomes with microkeratome-dissected and manually dissected donor tissue.

Authors:  Marianne O Price; Francis W Price
Journal:  Ophthalmology       Date:  2006-08-28       Impact factor: 12.079

5.  Current indications and surgical approaches to corneal transplants at the University of Toronto: A clinical-pathological study.

Authors:  Ryan Le; Narain Yucel; Shireen Khattak; Yeni H Yucel; Gerald J Prud'homme; Neeru Gupta
Journal:  Can J Ophthalmol       Date:  2016-09-07       Impact factor: 1.882

6.  Endothelial keratoplasty: the use of viscoelastic as an aid in reattaching the dislocated graft in abnormally structured eyes.

Authors:  Rong-Mei Peng; Yan-Sheng Hao; Hui-Jin Chen; Yan-Xiu Sun; Jing Hong
Journal:  Ophthalmology       Date:  2009-07-09       Impact factor: 12.079

7.  Novel technique in preparing a donor DSAEK lenticule in a patient with a glaucoma drainage device.

Authors:  W Sansanayudh; I Bahar; D Rootman
Journal:  Br J Ophthalmol       Date:  2009-09       Impact factor: 4.638

8.  Endothelial keratoplasty a simplified technique to minimize graft dislocation, iatrogenic graft failure, and pupillary block.

Authors:  Mark A Terry; Neda Shamie; Edwin S Chen; Karen L Hoar; Daniel J Friend
Journal:  Ophthalmology       Date:  2007-12-03       Impact factor: 12.079

9.  The role of postoperative positioning after DSAEK in preventing graft dislocation.

Authors:  Marit Saethre; Liv Drolsum
Journal:  Acta Ophthalmol       Date:  2012-09-19       Impact factor: 3.761

10.  Evolving surgical techniques of and indications for corneal transplantation in Ontario: 2000 - 2012.

Authors:  Angela Qiao Zhang; Darya Rubenstein; Aryeh Joshua Price; Elie Côté; Max Levitt; Linda Sharpen; Allan Slomovic
Journal:  Can J Ophthalmol       Date:  2013-06       Impact factor: 1.882

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