Literature DB >> 32456747

Is There a Functional Relation Between Set Shifting and Hyperactivity in Children with Attention-Deficit/Hyperactivity Disorder (ADHD)?

Lauren N Irwin1, Nicole B Groves1, Elia F Soto1, Michael J Kofler1.   

Abstract

OBJECTIVE: Replicated evidence indicates that children with attention-deficit/hyperactivity disorder (ADHD) show disproportionate increases in hyperactivity/physical movement when their underdeveloped executive functions are taxed. However, our understanding of hyperactivity's relation with set shifting is limited, which is surprising given set shifting's importance as the third core executive function alongside working memory and inhibition. The aim of this study was to experimentally examine the effect of imposing set shifting and inhibition demands on objectively measured activity level in children with and without ADHD.
METHOD: The current study used a validated experimental manipulation to differentially evoke set shifting, inhibition, and general cognitive demands in a carefully phenotyped sample of children aged 8-13 years with ADHD (n = 43) and without ADHD (n = 34). Activity level was sampled during each task using multiple, high-precision actigraphs; total hyperactivity scores (THS) were calculated.
RESULTS: Results of the 2 × 5 Bayesian ANOVA for hyperactivity revealed strong support for a main effect of task (BF10 = 1.79 × 1018, p < .001, ω2 = .20), such that children upregulated their physical movement in response to general cognitive demands and set shifting demands specifically, but not in response to increased inhibition demands. Importantly, however, this manipulation did not disproportionally increase hyperactivity in ADHD as demonstrated by significant evidence against the task × group interaction (BF01 = 18.21, p = .48, ω2 = .002).
CONCLUSIONS: Inhibition demands do not cause children to upregulate their physical activity. Set shifting produces reliable increases in children's physical movement/hyperactivity over and above the effects of general cognitive demands but cannot specifically explain hyperactivity in children with ADHD.

Entities:  

Keywords:  ADHD; Cognitive flexibility; Executive function; Global–local; Hyperactivity; Set shifting

Year:  2020        PMID: 32456747      PMCID: PMC7658020          DOI: 10.1017/S1355617720000545

Source DB:  PubMed          Journal:  J Int Neuropsychol Soc        ISSN: 1355-6177            Impact factor:   2.892


  31 in total

1.  Do children with attention-deficit/hyperactivity disorder (ADHD) have set shifting deficits?

Authors:  Lauren N Irwin; Michael J Kofler; Elia F Soto; Nicole B Groves
Journal:  Neuropsychology       Date:  2019-04-04       Impact factor: 3.295

2.  Validity of DSM-IV attention deficit/hyperactivity disorder symptom dimensions and subtypes.

Authors:  Erik G Willcutt; Joel T Nigg; Bruce F Pennington; Mary V Solanto; Luis A Rohde; Rosemary Tannock; Sandra K Loo; Caryn L Carlson; Keith McBurnett; Benjamin B Lahey
Journal:  J Abnorm Psychol       Date:  2012-05-21

Review 3.  Behavioral inhibition, sustained attention, and executive functions: constructing a unifying theory of ADHD.

Authors:  Russell A Barkley
Journal:  Psychol Bull       Date:  1997-01       Impact factor: 17.737

4.  Working Memory and Increased Activity Level (Hyperactivity) in ADHD: Experimental Evidence for a Functional Relation.

Authors:  Michael J Kofler; Dustin E Sarver; Erica L Wells
Journal:  J Atten Disord       Date:  2015-10-21       Impact factor: 3.256

5.  Is hyperactivity ubiquitous in ADHD or dependent on environmental demands? Evidence from meta-analysis.

Authors:  Michael J Kofler; Joseph S Raiker; Dustin E Sarver; Erica L Wells; Elia F Soto
Journal:  Clin Psychol Rev       Date:  2016-04-13

Review 6.  Moderators of working memory deficits in children with attention-deficit/hyperactivity disorder (ADHD): a meta-analytic review.

Authors:  Lisa J Kasper; R Matt Alderson; Kristen L Hudec
Journal:  Clin Psychol Rev       Date:  2012-07-17

7.  Behavior ratings of executive function among preschoolers with ADHD.

Authors:  E Mark Mahone; Jennifer Hoffman
Journal:  Clin Neuropsychol       Date:  2007-07       Impact factor: 3.535

8.  The Clinical Utility of the Behavior Rating Inventory of Executive Function (BRIEF) in the diagnosis of ADHD.

Authors:  Stephen McCandless; Liz O' Laughlin
Journal:  J Atten Disord       Date:  2007-05       Impact factor: 3.256

9.  The shift from local to global visual processing in 6-year-old children is associated with grey matter loss.

Authors:  Nicolas Poirel; Grégory Simon; Mathieu Cassotti; Gaëlle Leroux; Guy Perchey; Céline Lanoë; Amélie Lubin; Marie-Renée Turbelin; Sandrine Rossi; Arlette Pineau; Olivier Houdé
Journal:  PLoS One       Date:  2011-06-08       Impact factor: 3.240

10.  Bayesian inference for psychology. Part II: Example applications with JASP.

Authors:  Eric-Jan Wagenmakers; Jonathon Love; Maarten Marsman; Tahira Jamil; Alexander Ly; Josine Verhagen; Ravi Selker; Quentin F Gronau; Damian Dropmann; Bruno Boutin; Frans Meerhoff; Patrick Knight; Akash Raj; Erik-Jan van Kesteren; Johnny van Doorn; Martin Šmíra; Sacha Epskamp; Alexander Etz; Dora Matzke; Tim de Jong; Don van den Bergh; Alexandra Sarafoglou; Helen Steingroever; Koen Derks; Jeffrey N Rouder; Richard D Morey
Journal:  Psychon Bull Rev       Date:  2018-02
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  2 in total

1.  Executive functions and writing skills in children with and without ADHD.

Authors:  Elia F Soto; Lauren N Irwin; Elizabeth S M Chan; Jamie A Spiegel; Michael J Kofler
Journal:  Neuropsychology       Date:  2021-09-27       Impact factor: 3.295

2.  Actigraph-Measured Movement Correlates of Attention-Deficit/Hyperactivity Disorder (ADHD) Symptoms in Young People with Tuberous Sclerosis Complex (TSC) with and without Intellectual Disability and Autism Spectrum Disorder (ASD).

Authors:  Tom Earnest; Elizabeth Shephard; Charlotte Tye; Fiona McEwen; Emma Woodhouse; Holan Liang; Fintan Sheerin; Patrick F Bolton
Journal:  Brain Sci       Date:  2020-07-28
  2 in total

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