Ting Lei1, Hu Qian1, Long Hua1, Guilherme Moreira de Abreu E Silva2,3, Yihe Hu4, Pengfei Lei5. 1. Department of Orthopeadic Surgery, Xiangya Hospital Central South University, Changsha, 410008, China. 2. Federal University of Minas Gerais, Belo Horizonte, MG, Brazil. 3. Felício Rocho Hospital, Belo Horizonte, MG, Brazil. 4. Department of Orthopeadic Surgery, Xiangya Hospital Central South University, Changsha, 410008, China. csuhuyihe@163.com. 5. Department of Orthopeadic Surgery, Xiangya Hospital Central South University, Changsha, 410008, China. pengfeilei@csu.edu.cn.
Abstract
INTRODUCTION: The aim of this study is to provide an updated meta-analysis comparing the benefits and clinical outcomes between high flexion (HF)-TKA and standard (S)-TKA. MATERIALS AND METHODS: A detailed database analysis was carried out using Web of Science, PubMed, EMBASE, Cochrane Library, MEDLINE and Clinicaltrial.gov, to identify eligible studies. The meta-analysis and sensitivity analysis were performed using Review Manager 5.3 software and STATA 12.0. RESULTS: Twenty-two randomized control trials (RCTs), including 2841 patients and 4268 knees, were eligible for the meta-analysis. The pooled results of subgroup analysis reveal that there was significant difference between HF-TKA and S-TKA in each subgroup in terms of postoperative ROM, with a higher degree of knee flexion for HF-TKA than S-TKA. However, no statistical difference was identified between HF-TKA and S-TKA in other clinical outcomes including various functional scores and complications. CONCLUSIONS: On the basis of this meta-analysis, we can recommended HF-TKA as an alternative choice to S-TKA for patients requiring higher knee flexion in their daily activities.
INTRODUCTION: The aim of this study is to provide an updated meta-analysis comparing the benefits and clinical outcomes between high flexion (HF)-TKA and standard (S)-TKA. MATERIALS AND METHODS: A detailed database analysis was carried out using Web of Science, PubMed, EMBASE, Cochrane Library, MEDLINE and Clinicaltrial.gov, to identify eligible studies. The meta-analysis and sensitivity analysis were performed using Review Manager 5.3 software and STATA 12.0. RESULTS: Twenty-two randomized control trials (RCTs), including 2841 patients and 4268 knees, were eligible for the meta-analysis. The pooled results of subgroup analysis reveal that there was significant difference between HF-TKA and S-TKA in each subgroup in terms of postoperative ROM, with a higher degree of knee flexion for HF-TKA than S-TKA. However, no statistical difference was identified between HF-TKA and S-TKA in other clinical outcomes including various functional scores and complications. CONCLUSIONS: On the basis of this meta-analysis, we can recommended HF-TKA as an alternative choice to S-TKA for patients requiring higher knee flexion in their daily activities.
Entities:
Keywords:
High flexion; Meta-analysis; Randomized controlled trials; Range of motion; Total knee arthroplasty
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