Literature DB >> 32446977

CRISPR-Cas9 system: A genome-editing tool with endless possibilities.

Swati Tyagi1, Robin Kumar2, Aparup Das3, So Youn Won4, Pratyoosh Shukla5.   

Abstract

The discovery of CRISPR: Cas9 and its application as a powerful gene-editing tool has transformed the world of basic and applied science, especially the molecular biology dome. Also, the smooth, quick, flexible, and very efficient nature of this technology has enabled the biologists to alter the genome of prokaryotes to complex eukaryotic systems, including plants and animals. Using CRISPR and associated tools, investigation, control, and modification of significant biological events have been more accessible than before. These biological scissors are now being used to accelerate breeding programs of crop and livestock, engineer new antimicrobials, and control disease-carrying pathogens. However, like other techniques, these cutters emerged as a double-edged sword and put several challenges to the scientific society. Here in this review article, we summarized the beneficial application of the CRISPR: Cas9 system and unsafe perception to the society if handled carelessly. We also discussed the limitations and ethical issues related to CRISPR: Cas9 technology.
Copyright © 2020 Elsevier B.V. All rights reserved.

Keywords:  Agriculture; CRISPR-Cas9; Clinical applications; Industrial; Therapeutics

Mesh:

Year:  2020        PMID: 32446977     DOI: 10.1016/j.jbiotec.2020.05.008

Source DB:  PubMed          Journal:  J Biotechnol        ISSN: 0168-1656            Impact factor:   3.307


  10 in total

Review 1.  CRISPR/Cas9 technology for improving agronomic traits and future prospective in agriculture.

Authors:  Muhammad Junaid Rao; Lingqiang Wang
Journal:  Planta       Date:  2021-09-08       Impact factor: 4.116

2.  CRISPR/Cas9 mediated genome editing tools and their possible role in disease resistance mechanism.

Authors:  Diksha Kumari; Bishun Deo Prasad; Padmanabh Dwivedi; Akash Hidangmayum; Sangita Sahni
Journal:  Mol Biol Rep       Date:  2022-09-14       Impact factor: 2.742

Review 3.  Microbiome engineering for bioremediation of emerging pollutants.

Authors:  L Paikhomba Singha; Pratyoosh Shukla
Journal:  Bioprocess Biosyst Eng       Date:  2022-08-27       Impact factor: 3.434

4.  Increasing the Specificity of AAV-Based Gene Editing through Self-Targeting and Short-Promoter Strategies.

Authors:  Camilo Breton; Thomas Furmanak; Alexa N Avitto; Melanie K Smith; Caitlin Latshaw; Hanying Yan; Jenny A Greig; James M Wilson
Journal:  Mol Ther       Date:  2020-12-25       Impact factor: 11.454

Review 5.  Advances and Perspectives in the Application of CRISPR-Cas9 in Livestock.

Authors:  Abdul Jabbar; Farheen Zulfiqar; Mahnoor Mahnoor; Nadia Mushtaq; Muhammad Hamza Zaman; Anum Salah Ud Din; Musarrat Abbas Khan; Hafiz Ishfaq Ahmad
Journal:  Mol Biotechnol       Date:  2021-05-26       Impact factor: 2.695

Review 6.  CRISPR/Cas9 in Planta Hairy Root Transformation: A Powerful Platform for Functional Analysis of Root Traits in Soybean.

Authors:  Mohsen Niazian; François Belzile; Davoud Torkamaneh
Journal:  Plants (Basel)       Date:  2022-04-12

7.  Cell Factory Engineering of Undomesticated Bacillus Strains Using a Modified Integrative and Conjugative Element for Efficient Plasmid Delivery.

Authors:  Da-Eun Jeong; Man Su Kim; Ha-Rim Kim; Soo-Keun Choi
Journal:  Front Microbiol       Date:  2022-04-26       Impact factor: 6.064

Review 8.  DGK and DZHK position paper on genome editing: basic science applications and future perspective.

Authors:  Ralf P Brandes; Anne Dueck; Stefan Engelhardt; Manuel Kaulich; Christian Kupatt; Maria Teresa De Angelis; Matthias S Leisegang; Ferdinand le Noble; Alessandra Moretti; Oliver J Müller; Boris V Skryabin; Thomas Thum; Wolfgang Wurst
Journal:  Basic Res Cardiol       Date:  2021-01-15       Impact factor: 17.165

Review 9.  Genomic Analysis, Progress and Future Perspectives in Dairy Cattle Selection: A Review.

Authors:  Miguel A Gutierrez-Reinoso; Pedro M Aponte; Manuel Garcia-Herreros
Journal:  Animals (Basel)       Date:  2021-02-25       Impact factor: 3.231

Review 10.  Advances in Editing Silkworms (Bombyx mori) Genome by Using the CRISPR-Cas System.

Authors:  Gabriela-Maria Baci; Alexandra-Antonia Cucu; Alexandru-Ioan Giurgiu; Adriana-Sebastiana Muscă; Lilla Bagameri; Adela Ramona Moise; Otilia Bobiș; Attila Cristian Rațiu; Daniel Severus Dezmirean
Journal:  Insects       Date:  2021-12-27       Impact factor: 2.769

  10 in total

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