| Literature DB >> 32446977 |
Swati Tyagi1, Robin Kumar2, Aparup Das3, So Youn Won4, Pratyoosh Shukla5.
Abstract
The discovery of CRISPR: Cas9 and its application as a powerful gene-editing tool has transformed the world of basic and applied science, especially the molecular biology dome. Also, the smooth, quick, flexible, and very efficient nature of this technology has enabled the biologists to alter the genome of prokaryotes to complex eukaryotic systems, including plants and animals. Using CRISPR and associated tools, investigation, control, and modification of significant biological events have been more accessible than before. These biological scissors are now being used to accelerate breeding programs of crop and livestock, engineer new antimicrobials, and control disease-carrying pathogens. However, like other techniques, these cutters emerged as a double-edged sword and put several challenges to the scientific society. Here in this review article, we summarized the beneficial application of the CRISPR: Cas9 system and unsafe perception to the society if handled carelessly. We also discussed the limitations and ethical issues related to CRISPR: Cas9 technology.Keywords: Agriculture; CRISPR-Cas9; Clinical applications; Industrial; Therapeutics
Mesh:
Year: 2020 PMID: 32446977 DOI: 10.1016/j.jbiotec.2020.05.008
Source DB: PubMed Journal: J Biotechnol ISSN: 0168-1656 Impact factor: 3.307