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Literature DB >> 3244659

Turbuhaler: a new powder inhaler for administration of drugs to the airways.

Abstract

A metered-dose powder inhaler system has been developed. It is a multidose system that is easy to load and handle for the patient and that does not demand coordination between activation and inhalation. In addition, the new inhaler system is free of propellants, carriers, and other drug additives. Terbutaline sulfate has been selected as a suitable compound for evaluation of this inhaler. Clinical tests with the Turbuhaler have been performed and it has been compared with the conventional terbutaline pressurized metered-dose inhaler (MDI). The new powder inhaler can even be used at low inspiratory flow rates such as those present during acute asthma attacks.

Entities: Chemical Disease Species

Mesh：

Substances：
Powders
Terbutaline

Year: 1988 PMID： 3244659 DOI： 10.1023/a:1015969324799

Source DB: PubMed Journal: Pharm Res ISSN： 0724-8741 Impact factor: 4.200

4 in total

1. Dry powder aerosols. I. A new powder inhalation device.

Authors: J H Bell; P S Hartley; J S Cox
Journal: J Pharm Sci Date: 1971-10 Impact factor: 3.534

2. Problems patients have using pressurized aerosol inhalers.

Authors: G K Crompton
Journal: Eur J Respir Dis Suppl Date: 1982

3. Salbutamol powder inhalation for bronchial asthma.

Authors: N I Kjellman
Journal: Allergy Date: 1981-08 Impact factor: 13.146

4. Metered dose inhaler induced bronchospasm in asthmatic patients.

Authors: J Yarbrough; L E Mansfield; S Ting
Journal: Ann Allergy Date: 1985-07

4 in total

12 in total

Review 1. Inhaler devices for the treatment of asthma and chronic obstructive airways disease (COPD).

Authors: J Wright; D Brocklebank; F Ram
Journal: Qual Saf Health Care Date: 2002-12

2. Characterisation of a carrier-free dry powder aerosol formulation using inertial impaction and laser diffraction.

Authors: Gary P Martin; Helen B MacRitchie; Christopher Marriott; Xian-Ming Zeng
Journal: Pharm Res Date: 2006-08-10 Impact factor: 4.200

3. Effects, side effects and plasma concentrations of terbutaline in adult asthmatics after inhaling from a dry powder inhaler device at different inhalation flows and volumes.

Authors: T Engel; B Scharling; B Skovsted; J H Heinig
Journal: Br J Clin Pharmacol Date: 1992-04 Impact factor: 4.335

4. Aerosol electrostatics. I: Properties of fine powders before and after aerosolization by dry powder inhalers.

Authors: P R Byron; J Peart; J N Staniforth
Journal: Pharm Res Date: 1997-06 Impact factor: 4.200

5. Identical efficacy of terbutaline multidose dry powder inhaler prior to and after 4 weeks of use by asthmatic patients.

Authors: R A Stallaert
Journal: Eur J Clin Pharmacol Date: 1995 Impact factor: 2.953

6. Adhesion of powders for inhalation: an evaluation of drug detachment from surfaces following deposition from aerosol streams.

Authors: Martyn J Clarke; Joanne Peart; Stefano Cagnani; Peter R Byron
Journal: Pharm Res Date: 2002-03 Impact factor: 4.200

7. Effect of a volumatic spacer and mouth rinsing on systemic absorption of inhaled corticosteroids from a metered dose inhaler and dry powder inhaler.

Authors: O Selroos; M Halme
Journal: Thorax Date: 1991-12 Impact factor: 9.139