Literature DB >> 32439748

Acute ischaemic stroke following cisplatin-based chemotherapy for testicular cancer.

Yada Kanjanapan1,2, Daniel Gilbourd3, Ganesalingam Pranavan4,2.   

Abstract

Cisplatin is a widely used chemotherapeutic agent for many cancer types. Its toxicity profile includes drug-induced vascular damage. Clinicians should be aware of its varied presentation, including acute and chronic vascular events involving the arterial and venous system. This is a case of an otherwise well 32-year-old man with testicular cancer who received bleomycin/etoposide/cisplatin, and presented following two cycles of chemotherapy with homonymous hemianopia secondary to acute stroke. Acute arterial complications are rare, but clinicians should maintain a high index of suspicion for such events, even in a patient who otherwise has no vascular risk factors. Primary and secondary prevention measures including lifestyle modifications (smoking cessation, diet and exercise), blood pressure and cholesterol management, and antiplatelet therapy should be considered in patients exposed to cisplatin, during and following their treatment. © BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  chemotherapy; stroke; urological cancer

Mesh:

Substances:

Year:  2020        PMID: 32439748      PMCID: PMC7247405          DOI: 10.1136/bcr-2020-235005

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  12 in total

1.  Apixaban to Prevent Venous Thromboembolism in Patients with Cancer.

Authors:  Marc Carrier; Karim Abou-Nassar; Ranjeeta Mallick; Vicky Tagalakis; Sudeep Shivakumar; Ariah Schattner; Philip Kuruvilla; Danny Hill; Silvana Spadafora; Katerine Marquis; Mateya Trinkaus; Anna Tomiak; Agnes Y Y Lee; Peter L Gross; Alejandro Lazo-Langner; Robert El-Maraghi; Glenwood Goss; Gregoire Le Gal; David Stewart; Timothy Ramsay; Marc Rodger; Debra Witham; Philip S Wells
Journal:  N Engl J Med       Date:  2018-12-04       Impact factor: 91.245

2.  High incidence of thromboembolic events in patients treated with cisplatin-based chemotherapy: a large retrospective analysis.

Authors:  Russell A Moore; Nelly Adel; Elyn Riedel; Manisha Bhutani; Darren R Feldman; Nour Elise Tabbara; Gerald Soff; Rekha Parameswaran; Hani Hassoun
Journal:  J Clin Oncol       Date:  2011-08-01       Impact factor: 44.544

Review 3.  Thromboembolic events during chemotherapy for germ cell cancer: a cohort study and review of the literature.

Authors:  N I Weijl; M F Rutten; A H Zwinderman; H J Keizer; M A Nooy; F R Rosendaal; F J Cleton; S Osanto
Journal:  J Clin Oncol       Date:  2000-05       Impact factor: 44.544

4.  Phase III trial in metastatic gastroesophageal adenocarcinoma with fluorouracil, leucovorin plus either oxaliplatin or cisplatin: a study of the Arbeitsgemeinschaft Internistische Onkologie.

Authors:  Salah-Eddin Al-Batran; Joerg Thomas Hartmann; Stephan Probst; Harald Schmalenberg; Stephan Hollerbach; Ralf Hofheinz; Volker Rethwisch; Gernot Seipelt; Nils Homann; Gerhard Wilhelm; Gunter Schuch; Jan Stoehlmacher; Hans Günter Derigs; Susanna Hegewisch-Becker; Johannes Grossmann; Claudia Pauligk; Akin Atmaca; Carsten Bokemeyer; Alexander Knuth; Elke Jäger
Journal:  J Clin Oncol       Date:  2008-03-20       Impact factor: 44.544

Review 5.  Risk of venous thromboembolism in patients with cancer treated with Cisplatin: a systematic review and meta-analysis.

Authors:  Sonia Seng; Ziyue Liu; Sophia K Chiu; Tracy Proverbs-Singh; Guru Sonpavde; Toni K Choueiri; Che-Kai Tsao; Menggang Yu; Noah M Hahn; William K Oh; Matthew D Galsky
Journal:  J Clin Oncol       Date:  2012-11-13       Impact factor: 44.544

6.  Cerebrovascular accident after chemotherapy for testicular cancer.

Authors:  Bulent Karagoz; Oguz Bilgi; Ilker Akyol; Alpaslan Ozgun; Orhan Turken; Emin Gokhan Kandemir
Journal:  Mil Med       Date:  2009-03       Impact factor: 1.437

7.  Development and validation of a predictive model for chemotherapy-associated thrombosis.

Authors:  Alok A Khorana; Nicole M Kuderer; Eva Culakova; Gary H Lyman; Charles W Francis
Journal:  Blood       Date:  2008-01-23       Impact factor: 22.113

8.  Cerebrovascular accident during cisplatin-based combination chemotherapy of testicular germ cell tumor: an unusual case report.

Authors:  Alper Azak; Berna Oksüzoğlu; Tağmaç Deren; Birgül Müftüoğlu Oneç; Nurullah Zengin
Journal:  Anticancer Drugs       Date:  2008-01       Impact factor: 2.248

9.  Nadroparin for the prevention of thromboembolic events in ambulatory patients with metastatic or locally advanced solid cancer receiving chemotherapy: a randomised, placebo-controlled, double-blind study.

Authors:  Giancarlo Agnelli; Gualberto Gussoni; Carlo Bianchini; Melina Verso; Mario Mandalà; Luigi Cavanna; Sandro Barni; Roberto Labianca; Franco Buzzi; Giovanni Scambia; Rodolfo Passalacqua; Sergio Ricci; Giampietro Gasparini; Vito Lorusso; Erminio Bonizzoni; Maurizio Tonato
Journal:  Lancet Oncol       Date:  2009-08-31       Impact factor: 41.316

10.  Arterial emboli complicating Cisplatin therapy.

Authors:  Campbell D Tait; Elaine M Rankin
Journal:  Case Rep Oncol Med       Date:  2012-02-28
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