| Literature DB >> 32439748 |
Yada Kanjanapan1,2, Daniel Gilbourd3, Ganesalingam Pranavan4,2.
Abstract
Cisplatin is a widely used chemotherapeutic agent for many cancer types. Its toxicity profile includes drug-induced vascular damage. Clinicians should be aware of its varied presentation, including acute and chronic vascular events involving the arterial and venous system. This is a case of an otherwise well 32-year-old man with testicular cancer who received bleomycin/etoposide/cisplatin, and presented following two cycles of chemotherapy with homonymous hemianopia secondary to acute stroke. Acute arterial complications are rare, but clinicians should maintain a high index of suspicion for such events, even in a patient who otherwise has no vascular risk factors. Primary and secondary prevention measures including lifestyle modifications (smoking cessation, diet and exercise), blood pressure and cholesterol management, and antiplatelet therapy should be considered in patients exposed to cisplatin, during and following their treatment. © BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.Entities:
Keywords: chemotherapy; stroke; urological cancer
Mesh:
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Year: 2020 PMID: 32439748 PMCID: PMC7247405 DOI: 10.1136/bcr-2020-235005
Source DB: PubMed Journal: BMJ Case Rep ISSN: 1757-790X