Literature DB >> 32439747

Severe hypothermia, bradycardia and cardiac arrest in association with risperidone.

Nishant Sharma1, Sangeeta Bhat2, Divya Ravi2, Pius Ochieng3.   

Abstract

Antipsychotic medications, including risperidone, are widely used in the treatment of psychiatric disorders, including schizophrenia. While hyperthermia is an establish adverse effect of these medications, less is known about the rare occurrence of hypothermia. We present two patients who developed hypothermia, bradycardia and cardiac arrest in association with risperidone. We briefly review previously similarly reported cases. © BMJ Publishing Group Limited 2020. No commercial re-use. See rights and permissions. Published by BMJ.

Entities:  

Keywords:  psychiatry (drugs and medicines); unwanted effects / adverse reactions

Mesh:

Substances:

Year:  2020        PMID: 32439747      PMCID: PMC7247412          DOI: 10.1136/bcr-2020-234999

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  17 in total

Review 1.  De Novo delayed onset hypothermia secondary to therapeutic doses of risperidone in bipolar affective disorder.

Authors:  M A Lasitha Perera; Jegan Yogaratnam
Journal:  Ther Adv Psychopharmacol       Date:  2014-04

2.  History of the discovery and clinical introduction of chlorpromazine.

Authors:  Francisco López-Muñoz; Cecilio Alamo; Eduardo Cuenca; Winston W Shen; Patrick Clervoy; Gabriel Rubio
Journal:  Ann Clin Psychiatry       Date:  2005 Jul-Sep       Impact factor: 1.567

3.  Hypothermia in a patient receiving risperidone and paroxetine.

Authors:  M Obadah Al Chekakie; Jeffrey M Ketz; Christopher M Whinney
Journal:  J Clin Psychopharmacol       Date:  2006-06       Impact factor: 3.153

4.  Hypothermia induced by risperidone and olanzapine in a patient with Prader-Willi syndrome.

Authors:  T G Phan; R Y Yu; M I Hersch
Journal:  Med J Aust       Date:  1998-08-17       Impact factor: 7.738

Review 5.  Management of accidental hypothermia and cold injury.

Authors:  Patrizio Petrone; Juan A Asensio; Corrado P Marini
Journal:  Curr Probl Surg       Date:  2014-07-29       Impact factor: 1.909

6.  Atypical antipsychotic induced mild hypothermia.

Authors:  Alan Brevik; Debra Farver
Journal:  S D J Med       Date:  2003-02

7.  The enhancement of chlorpromazine-induced hypothermia by lesions in the anterior hypothalamus.

Authors:  C Y Chai; M T Lin
Journal:  Br J Pharmacol       Date:  1977-09       Impact factor: 8.739

8.  Possible long-acting risperidone-induced hypothermia precipitating phenytoin toxicity in an elderly patient.

Authors:  P Brandon Bookstaver; A D Miller
Journal:  J Clin Pharm Ther       Date:  2010-10-19       Impact factor: 2.512

9.  Mild Hypothermia in a Child with Low-Dose Risperidone.

Authors:  Katharina Grau; Paul L Plener; Maximilian Gahr; Christian Denzer; Roland W Freudenmann
Journal:  Z Kinder Jugendpsychiatr Psychother       Date:  2016-09-29

10.  Haloperidol produces hypothermic effects in rats.

Authors:  M T Lin; H S Wang; Z Wang; Y F Chern
Journal:  Experientia       Date:  1979-11-15
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