Atypical antipsychotic induced mild hypothermia.

Atypical antipsychotic induced hypothermia is a rare adverse effect that may present with mild to severe symptoms. This is a case report of subtle, mild hypothermia in a 54-year old female patient receiving risperidone for schizophrenia. A mild decrease in the temperature (33.4-34.7 degrees C) along with delusions and feeling slightly chilly was part of the initial presentation. The diagnosis of hypothermia was delayed until it was apparent for several days but resolved with the discontinuation of risperidone and continuation of clozapine. Evaluation of hypothermia with psychiatric patients should include primary accidental hypothermia, central nervous system disorders, metabolic disorders, infections, and medications.