Literature DB >> 324287

Single dose of two grams of metronidazole for Trichomonas vaginalis infection.

F J Fleury, W S Van Bergen, R L Prentice, J G Russell, J A Singleton, J V Standard.   

Abstract

In this study, 243 women with symptomatic trichomonal vaginitis were treated with eight 250 mg. tablets of metronidazole for themselves, and eight tablets were given to each of their male consorts. They were given instructions to ingest "all eight in a row" and "avoid alcohol for 48 hours." Ninety-five per cent of 203 women that returned for re-examination were cured. This single-dose treatment is effective, well tolerated, and less expensive than current recommended dosages.

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Year:  1977        PMID: 324287     DOI: 10.1016/0002-9378(77)90630-5

Source DB:  PubMed          Journal:  Am J Obstet Gynecol        ISSN: 0002-9378            Impact factor:   8.661


  5 in total

1.  The use of antimicrobial drugs in office practice.

Authors:  M R Achong
Journal:  Can Fam Physician       Date:  1982-12       Impact factor: 3.275

2.  A randomized treatment trial: single versus 7-day dose of metronidazole for the treatment of Trichomonas vaginalis among HIV-infected women.

Authors:  Patricia Kissinger; Leandro Mena; Judy Levison; Rebecca A Clark; Megan Gatski; Harold Henderson; Norine Schmidt; Susan L Rosenthal; Leann Myers; David H Martin
Journal:  J Acquir Immune Defic Syndr       Date:  2010-12-15       Impact factor: 3.731

3.  Secretion of drugs into the human female genital tract.

Authors:  I G Salas-Herrera; P Turner; R M Pearson
Journal:  Postgrad Med J       Date:  1991-08       Impact factor: 2.401

4.  Improvement of vaginal health for Kenyan women at risk for acquisition of human immunodeficiency virus type 1: results of a randomized trial.

Authors:  R Scott McClelland; Barbra A Richardson; Wisal M Hassan; Vrasha Chohan; Ludo Lavreys; Kishorchandra Mandaliya; James Kiarie; Walter Jaoko; Jeckoniah O Ndinya-Achola; Jared M Baeten; Ann E Kurth; King K Holmes
Journal:  J Infect Dis       Date:  2008-05-15       Impact factor: 5.226

5.  Metronidazole in a single dose for the treatment of trichomoniasis. Failure of a 1-g single dose.

Authors:  T W Austin; E A Smith; R Darwish; E D Ralph; F L Pattison
Journal:  Br J Vener Dis       Date:  1982-04
  5 in total

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