| Literature DB >> 32424708 |
Nina Stenberg1, Synnve Schjølberg2, Domenic V Cicchetti3, Frederick Shic4,5, Fred Volkmar3, Anne-Siri Øyen2,6, Michaeline Bresnahan7, Britt Kveim Svendsen1, Stephen von Tetzchner8, Nina Torheim Thronæs9, Suzanne Macari3, Katarzyna Chawarska3, Pål Suren2, Roald A Øien10,11.
Abstract
Early identification of autism spectrum disorder (ASD) is regarded as crucial for swift access to early intervention and, subsequently, better outcomes later in life. However, current instruments miss large proportions of children who later go on to be diagnosed with ASD, raising a question of what these instruments measure. The present study utilized data from the Norwegian Mother, Father, and Child Cohort Study and the Autism Birth Cohort study to explore the subsequent developmental and diagnostic characteristics of children raising developmental concern on the six-critical discriminative item criterion of the M-CHAT (DFA6) at 18 months of age (N = 834). The DFA6 identified 28.8% of children diagnosed with ASD (N = 163), but 4.4% with language disorder (N = 188) and 81.3% with intellectual disability (N = 32) without ASD. Scoring in the «at-risk» range was associated with lower IQ, impaired functional language, and greater severity of autism symptoms whether children had ASD or not.Entities:
Keywords: ADOS; Autism spectrum disorders; Cognition; Early identification; Father and child cohort study; Language; MoBa; Norwegian mother; Screening; Vineland
Mesh:
Year: 2021 PMID: 32424708 PMCID: PMC7954713 DOI: 10.1007/s10803-020-04539-8
Source DB: PubMed Journal: J Autism Dev Disord ISSN: 0162-3257