Min Won Ahn1, Ji Woong Lee2, Jong Hoon Shin3, Jong Soo Lee2. 1. Busan Sungmo Eye Hospital, Busan 48064, Korea. 2. Department of Ophthalmology, Pusan National University College of Medicine and Medical Research Institute of Pusan National University Hospital, Busan 49241, Korea. 3. Department of Ophthalmology, Pusan National University Yangsan Hospital, Yangsan 50612, Korea.
Abstract
AIM: To evaluate the correlation between intraocular pressure (IOP) and various obesity-related health factors in patients with ocular hypertension in Korea. METHODS: A total of 40 850 subjects underwent age, sex, body weight, and height assessments and automated multiphasic tests, including non-contact tonometry, automated perimetry, fundus photography, systolic/diastolic blood pressure measurement, and evaluation of obesity-related health parameters such as obesity index, body mass index (BMI), a body shape index (ABSI), and waist-to-height ratio (WtHR). Subjects were divided into ocular hypertension group and normal IOP group according to IOP after matching of age and sex. RESULTS: Of 40 850 participants, 1515 (3.7%) had ocular hypertension, and 1515 with normal IOP were selected as controls using propensity score matching. The mean IOP of control group was 15.3±2.3 mm Hg, compared with 23.3±1.6 mm Hg in ocular hypertension group. Height, obesity index, BMI, and WtHR in the ocular hypertension group were significantly higher than in the normal IOP group (P<0.001, P<0.001, P=0.009, P=0.002). IOP of ocular hypertension was positively correlated with obesity index (P=0.027) and BMI (P=0.016), whereas IOP of control was positively correlated with blood pressure (P<0.001, P=0.002), obesity index (P<0.001), BMI (P<0.001), and WHtR (P=0.002). Systolic blood pressure (β=0.022, P<0.001) and body weight (β=0.016, P=0.02) were precursors of IOP in normal subjects, but sex (male; β=-0.231, P=0.008) and obesity index (β=-0.007, P=0.017) were precursors of ocular hypertension according to multiple regression analysis. CONCLUSION: Among various obesity-related health parameters, obesity index is the best indicator for further increase in IOP in ocular hypertension group. International Journal of Ophthalmology Press.
AIM: To evaluate the correlation between intraocular pressure (IOP) and various obesity-related health factors in patients with ocular hypertension in Korea. METHODS: A total of 40 850 subjects underwent age, sex, body weight, and height assessments and automated multiphasic tests, including non-contact tonometry, automated perimetry, fundus photography, systolic/diastolic blood pressure measurement, and evaluation of obesity-related health parameters such as obesity index, body mass index (BMI), a body shape index (ABSI), and waist-to-height ratio (WtHR). Subjects were divided into ocular hypertension group and normal IOP group according to IOP after matching of age and sex. RESULTS: Of 40 850 participants, 1515 (3.7%) had ocular hypertension, and 1515 with normal IOP were selected as controls using propensity score matching. The mean IOP of control group was 15.3±2.3 mm Hg, compared with 23.3±1.6 mm Hg in ocular hypertension group. Height, obesity index, BMI, and WtHR in the ocular hypertension group were significantly higher than in the normal IOP group (P<0.001, P<0.001, P=0.009, P=0.002). IOP of ocular hypertension was positively correlated with obesity index (P=0.027) and BMI (P=0.016), whereas IOP of control was positively correlated with blood pressure (P<0.001, P=0.002), obesity index (P<0.001), BMI (P<0.001), and WHtR (P=0.002). Systolic blood pressure (β=0.022, P<0.001) and body weight (β=0.016, P=0.02) were precursors of IOP in normal subjects, but sex (male; β=-0.231, P=0.008) and obesity index (β=-0.007, P=0.017) were precursors of ocular hypertension according to multiple regression analysis. CONCLUSION: Among various obesity-related health parameters, obesity index is the best indicator for further increase in IOP in ocular hypertension group. International Journal of Ophthalmology Press.
Entities:
Keywords:
body mass index; body shape index; intraocular pressure; ocular hypertension; waist-to-height ratio
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