| Literature DB >> 32419161 |
Hanglong Wu1, Heiner Friedrich1,2, Joseph P Patterson3, Nico A J M Sommerdijk4, Niels de Jonge5,6.
Abstract
Innovations in liquid-phase electron microscopy (LP-EM) have made it possible to perform experiments at the optimized conditions needed to examine soft matter. The main obstacle is conducting experiments in such a way that electron beam radiation can be used to obtain answers for scientific questions without changing the structure and (bio)chemical processes in the sample due to the influence of the radiation. By overcoming these experimental difficulties at least partially, LP-EM has evolved into a new microscopy method with nanometer spatial resolution and sub-second temporal resolution for analysis of soft matter in materials science and biology. Both experimental design and applications of LP-EM for soft matter materials science and biological research are reviewed, and a perspective of possible future directions is given.Entities:
Keywords: beam-sample interactions; dynamic processes; in situ electron microscopy; synthetic materials
Mesh:
Substances:
Year: 2020 PMID: 32419161 DOI: 10.1002/adma.202001582
Source DB: PubMed Journal: Adv Mater ISSN: 0935-9648 Impact factor: 30.849