Literature DB >> 32412846

Electronic Medical Record Search Engine (EMERSE): An Information Retrieval Tool for Supporting Cancer Research.

David A Hanauer1, Jill S Barnholtz-Sloan2,3, Mark F Beno2,3, Guilherme Del Fiol4, Eric B Durbin5,6, Oksana Gologorskaya7, Daniel Harris5,6, Brett Harnett8, Kensaku Kawamoto4, Benjamin May9, Eric Meeks7, Emily Pfaff10, Janie Weiss9, Kai Zheng11.   

Abstract

PURPOSE: The Electronic Medical Record Search Engine (EMERSE) is a software tool built to aid research spanning cohort discovery, population health, and data abstraction for clinical trials. EMERSE is now live at three academic medical centers, with additional sites currently working on implementation. In this report, we describe how EMERSE has been used to support cancer research based on a variety of metrics.
METHODS: We identified peer-reviewed publications that used EMERSE through online searches as well as through direct e-mails to users based on audit logs. These logs were also used to summarize use at each of the three sites. Search terms for two of the sites were characterized using the natural language processing tool MetaMap to determine to which semantic types the terms could be mapped.
RESULTS: We identified a total of 326 peer-reviewed publications that used EMERSE through August 2019, although this is likely an underestimation of the true total based on the use log analysis. Oncology-related research comprised nearly one third (n = 105; 32.2%) of all research output. The use logs showed that EMERSE had been used by multiple people at each site (nearly 3,500 across all three) who had collectively logged into the system > 100,000 times. Many user-entered search queries could not be mapped to a semantic type, but the most common semantic type for terms that did match was "disease or syndrome," followed by "pharmacologic substance."
CONCLUSION: EMERSE has been shown to be a valuable tool for supporting cancer research. It has been successfully deployed at other sites, despite some implementation challenges unique to each deployment environment.

Entities:  

Year:  2020        PMID: 32412846      PMCID: PMC7265780          DOI: 10.1200/CCI.19.00134

Source DB:  PubMed          Journal:  JCO Clin Cancer Inform        ISSN: 2473-4276


  33 in total

1.  The Value of Unstructured Electronic Health Record Data in Geriatric Syndrome Case Identification.

Authors:  Hadi Kharrazi; Laura J Anzaldi; Leilani Hernandez; Ashwini Davison; Cynthia M Boyd; Bruce Leff; Joe Kimura; Jonathan P Weiner
Journal:  J Am Geriatr Soc       Date:  2018-07-04       Impact factor: 5.562

2.  The inevitable application of big data to health care.

Authors:  Travis B Murdoch; Allan S Detsky
Journal:  JAMA       Date:  2013-04-03       Impact factor: 56.272

3.  Accuracy of ICD-9-CM codes for identifying cardiovascular and stroke risk factors.

Authors:  Elena Birman-Deych; Amy D Waterman; Yan Yan; David S Nilasena; Martha J Radford; Brian F Gage
Journal:  Med Care       Date:  2005-05       Impact factor: 2.983

4.  Imaging appearance of well-differentiated liposarcomas with myxoid stroma.

Authors:  Yoav Morag; Corrie Yablon; Monica Kalume Brigido; Jon Jacobson; David Lucas
Journal:  Skeletal Radiol       Date:  2018-04-16       Impact factor: 2.199

5.  Multiclonality and Marked Branched Evolution of Low-Grade Endometrioid Endometrial Carcinoma.

Authors:  Lorena Lazo de la Vega; Mia C Samaha; Kevin Hu; Nolan R Bick; Javed Siddiqui; Daniel H Hovelson; Chia-Jen Liu; Cody S Carter; Kathleen R Cho; Andrew P Sciallis; Scott A Tomlins
Journal:  Mol Cancer Res       Date:  2019-01-04       Impact factor: 5.852

6.  Lessons Learned in the Development of a Computable Phenotype for Response in Myeloproliferative Neoplasms.

Authors:  Evan Sholle; Spencer Krichevsky; Joseph Scandura; Claudia Sosner; Thomas R Campion
Journal:  IEEE Int Conf Healthc Inform       Date:  2018-07-26

7.  Primary analysis of a phase II open-label trial of INCB039110, a selective JAK1 inhibitor, in patients with myelofibrosis.

Authors:  John O Mascarenhas; Moshe Talpaz; Vikas Gupta; Lynda M Foltz; Michael R Savona; Ronald Paquette; A Robert Turner; Paul Coughlin; Elliott Winton; Timothy C Burn; Peter O'Neill; Jason Clark; Deborah Hunter; Albert Assad; Ronald Hoffman; Srdan Verstovsek
Journal:  Haematologica       Date:  2016-10-27       Impact factor: 9.941

8.  Integration of Germline Pharmacogenetics Into a Tumor Sequencing Program.

Authors:  Daniel L Hertz; Andrew Glatz; Amy L Pasternak; Robert J Lonigro; Pankaj Vats; Yi-Mi Wu; Bailey Anderson; Erica Rabban; Erika Mora; Kevin Frank; Dan R Robinson; Rajen J Mody; Arul Chinnaiyan
Journal:  JCO Precis Oncol       Date:  2018-07-23

9.  ReCAP: Feasibility and Accuracy of Extracting Cancer Stage Information From Narrative Electronic Health Record Data.

Authors:  Jeremy L Warner; Mia A Levy; Michael N Neuss; Jeremy L Warner; Mia A Levy; Michael N Neuss
Journal:  J Oncol Pract       Date:  2015-08-25       Impact factor: 3.840

10.  Electronic Health Record Phenotypes for Identifying Patients with Late-Stage Disease: a Method for Research and Clinical Application.

Authors:  Natalie C Ernecoff; Kathryn L Wessell; Laura C Hanson; Adam M Lee; Christopher M Shea; Stacie B Dusetzina; Morris Weinberger; Antonia V Bennett
Journal:  J Gen Intern Med       Date:  2019-08-08       Impact factor: 5.128

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  3 in total

1.  Informatics Tools for Cancer Research and Care: Bridging the Gap Between Innovation and Implementation.

Authors:  Jeremy L Warner; Juli D Klemm
Journal:  JCO Clin Cancer Inform       Date:  2020-09

2.  Surgical Management of Rhabdomyosarcoma of the Nasal Cavity and Paranasal Sinuses: Analysis of Operative Indications, Settings, and Outcomes.

Authors:  Lulia A Kana; Joshua D Smith; Emily L Bellile; Rashmi Chugh; Erin L McKean
Journal:  J Neurol Surg B Skull Base       Date:  2021-11-08

3.  RUBY: Natural Language Processing of French Electronic Medical Records for Breast Cancer Research.

Authors:  Renaud Schiappa; Sara Contu; Dorian Culie; Brice Thamphya; Yann Chateau; Jocelyn Gal; Caroline Bailleux; Juliette Haudebourg; Jean-Marc Ferrero; Emmanuel Barranger; Emmanuel Chamorey
Journal:  JCO Clin Cancer Inform       Date:  2022-07
  3 in total

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