Literature DB >> 32406597

A change of heart: Preliminary results of the US 2018 adult heart allocation revision.

Rebecca R Goff1, Kimberly Uccellini1, Kelsi Lindblad1, Shelley Hall2, Ryan Davies3, Maryjane Farr4, Scott Silvestry5, Joseph G Rogers6.   

Abstract

In 2018, the Organ Procurement and Transplantation Network (OPTN) modified adult heart allocation to better stratify candidates and provide broader access to the most medically urgent candidates. We analyzed OPTN data that included waiting list and transplant characteristics, geographical distribution, and early outcomes 1 year before (pre: October 18, 2017-October 17, 2018) and following (post: October 18, 2018-October 17, 2019) implementation. The number of adult heart transplants increased from 2954 pre- to 3032 postimplementation. Seventy-eight percent of transplants in the post era were for the most medically urgent (statuses 1-3) compared to 68% for status 1A in the pre era. The median distance between the donor hospital and transplant center increased from 83 to 216 nautical miles, with an increase in total ischemic time from 3 to 3.4 hours (all P < .001). Waiting list mortality was not different across eras (14.8 vs 14.9 deaths per 100 patient-years pre vs post respectively). Posttransplant patient survival was not different, 93.6% pre and 92.8% post. There is early evidence that the heart allocation policy has enhanced stratification of candidates by their medical urgency and broader distribution for the most medically urgent candidates with minimal impact on overall waiting list mortality and posttransplant outcomes.
© 2020 The American Society of Transplantation and the American Society of Transplant Surgeons.

Entities:  

Keywords:  Organ Procurement and Transplantation Network (OPTN); clinical research/practice; health services and outcomes research; heart disease; heart transplantation/cardiology; organ allocation; organ procurement and allocation; patient survival; statistics

Mesh:

Year:  2020        PMID: 32406597     DOI: 10.1111/ajt.16010

Source DB:  PubMed          Journal:  Am J Transplant        ISSN: 1600-6135            Impact factor:   8.086


  21 in total

1.  Comparing outcomes for infiltrative and restrictive cardiomyopathies under the new heart transplant allocation system.

Authors:  Jan M Griffin; Ersilia M DeFilippis; Hannah Rosenblum; Veli K Topkara; Justin A Fried; Nir Uriel; Koji Takeda; Maryjane A Farr; Mathew S Maurer; Kevin J Clerkin
Journal:  Clin Transplant       Date:  2020-10-28       Impact factor: 2.863

2.  Twelfth Interagency Registry for Mechanically Assisted Circulatory Support Report: Readmissions After Left Ventricular Assist Device.

Authors:  Palak Shah; Melana Yuzefpolskaya; Gavin W Hickey; Khadijah Breathett; Omar Wever-Pinzon; Van-Khue Ton; William Hiesinger; Devin Koehl; James K Kirklin; Ryan S Cantor; Jeffrey P Jacobs; Robert H Habib; Francis D Pagani; Daniel J Goldstein
Journal:  Ann Thorac Surg       Date:  2022-01-07       Impact factor: 4.330

3.  Recovery With Temporary Mechanical Circulatory Support While Waitlisted for Heart Transplantation.

Authors:  Veli K Topkara; Gabriel T Sayer; Kevin J Clerkin; Omar Wever-Pinzon; Koji Takeda; Hiroo Takayama; Craig H Selzman; Yoshifumi Naka; Daniel Burkhoff; Josef Stehlik; Maryjane A Farr; James C Fang; Nir Uriel; Stavros G Drakos
Journal:  J Am Coll Cardiol       Date:  2022-03-08       Impact factor: 24.094

Review 4.  Critically appraising the 2018 United Network for Organ Sharing donor allocation policy: adding life boats or rearranging the deck chairs?

Authors:  Lauren K Truby; Maryjane Farr; Veli K Topkara
Journal:  Curr Opin Anaesthesiol       Date:  2022-02-01       Impact factor: 2.706

5.  Impact of Temporary Percutaneous Mechanical Circulatory Support Before Transplantation in the 2018 Heart Allocation System.

Authors:  Kevin J Clerkin; Oluwafeyijimi Salako; Justin A Fried; Jan M Griffin; Jayant Raikhelkar; Rashmi Jain; Susan Restaino; Paolo C Colombo; Koji Takeda; Maryjane A Farr; Gabriel Sayer; Nir Uriel; Veli K Topkara
Journal:  JACC Heart Fail       Date:  2021-11-10       Impact factor: 12.035

6.  Relationships between 2018 UNOS heart policy and transplant outcomes in metropolitan, micropolitan, and rural settings.

Authors:  Khadijah Breathett; Shannon M Knapp; Daniel Addison; Amber Johnson; Rashmee U Shah; Kelsey Flint; Harriette G C Van Spall; Nancy K Sweitzer; Sula Mazimba
Journal:  J Heart Lung Transplant       Date:  2022-06-26       Impact factor: 13.569

Review 7.  Disparities in heart and lung transplantation.

Authors:  Wayne Tsuang; Rola Khedraki; Eileen Hsich
Journal:  Curr Opin Organ Transplant       Date:  2021-10-01       Impact factor: 2.269

8.  Outcomes in the 2018 UNOS donor heart allocation system: A perspective on disparate analyses.

Authors:  Anubodh S Varshney; Sameer A Hirji; Michael M Givertz
Journal:  J Heart Lung Transplant       Date:  2020-08-26       Impact factor: 10.247

9.  Between-center variation in high-priority listing status under the new heart allocation policy.

Authors:  Gege Ran; Kevin Chung; Allen S Anderson; Robert D Gibbons; Nikhil Narang; Matthew M Churpek; William F Parker
Journal:  Am J Transplant       Date:  2021-05-05       Impact factor: 8.086

10.  Exception Status Listing in the New Adult Heart Allocation System: A New Solution to an Old Problem?

Authors:  Veli K Topkara; Kevin J Clerkin; Justin A Fried; Jan Griffin; Jayant Raikhelkar; Sun Hi Lee; Farhana Latif; Marlena Habal; Evelyn Horn; Maryjane A Farr; Koji Takada; Yoshifumi Naka; Ulrich P Jorde; Gabriel Sayer; Nir Uriel
Journal:  Circ Heart Fail       Date:  2021-05-28       Impact factor: 10.447

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