AlBandary Hassan AlJameel1, Sultan A Almalki2. 1. Department of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh, Saudi Arabia. 2. Department of Preventive Dental Sciences, College of Dentistry, Prince Sattam Bin Abdulaziz University, Alkharj, Saudi Arabia.
Abstract
OBJECTIVES: To assess the efficacy of triphala mouthwash (TRP-MW) in being equally effective to chlorhexidine mouthwash (CHX-MW) in the treatment of plaque-induced gingivitis. MATERIALS AND METHODS: Electronic searches in MEDLINE/PubMed, EMBASE and CENTRAL were conducted in databases up to April 2020. Randomized clinical trials (RCTs) comparing clinical efficacy of TRP-MW (test group) in comparison with CHX-MW in treating plaque-induced gingivitis were considered. The primary outcome was gingival index (GI), whereas the secondary outcome was plaque index (PI). RESULTS: Seven RCTs were included. All studies showed that TRP-MW administration was significantly effective as compared to CHX-MW in the treatment of plaque-induced gingivitis. Considering the effects of TRP-MW on clinical gingival inflammatory parameters, significant heterogeneity for both GI (χ2 = 72.77, P < .0001, I2 = 91.76%) and PI (χ2 = 153.67, P < .0001, I2 = 96.10%) was observed between both TRP-MW and CHX-MW groups. The overall mean difference for both GI (WMD = -0.29, 95% CI = -0.40 to -0.17, P < .001) and PI (WMD = -0.43, 95% CI = -0.54 to -0.31, P < .001) was statistically significant between TRP-MW and CHX-MW at follow-up, respectively. CONCLUSION: Triphala mouthwash seems to significantly improve the clinical gingival inflammatory parameters in plaque-induced gingivitis with equal clinical efficacy as CHX-MW. TRP is a cost-effective alternative and is easily available with limited side effects on periodontal tissues.
OBJECTIVES: To assess the efficacy of triphala mouthwash (TRP-MW) in being equally effective to chlorhexidine mouthwash (CHX-MW) in the treatment of plaque-induced gingivitis. MATERIALS AND METHODS: Electronic searches in MEDLINE/PubMed, EMBASE and CENTRAL were conducted in databases up to April 2020. Randomized clinical trials (RCTs) comparing clinical efficacy of TRP-MW (test group) in comparison with CHX-MW in treating plaque-induced gingivitis were considered. The primary outcome was gingival index (GI), whereas the secondary outcome was plaque index (PI). RESULTS: Seven RCTs were included. All studies showed that TRP-MW administration was significantly effective as compared to CHX-MW in the treatment of plaque-induced gingivitis. Considering the effects of TRP-MW on clinical gingival inflammatory parameters, significant heterogeneity for both GI (χ2 = 72.77, P < .0001, I2 = 91.76%) and PI (χ2 = 153.67, P < .0001, I2 = 96.10%) was observed between both TRP-MW and CHX-MW groups. The overall mean difference for both GI (WMD = -0.29, 95% CI = -0.40 to -0.17, P < .001) and PI (WMD = -0.43, 95% CI = -0.54 to -0.31, P < .001) was statistically significant between TRP-MW and CHX-MW at follow-up, respectively. CONCLUSION: Triphala mouthwash seems to significantly improve the clinical gingival inflammatory parameters in plaque-induced gingivitis with equal clinical efficacy as CHX-MW. TRP is a cost-effective alternative and is easily available with limited side effects on periodontal tissues.