| Literature DB >> 32364214 |
Marissa E Wechsler1, H K H Jocelyn Dang, Samuel D Dahlhauser, Susana P Simmonds, James F Reuther, Jordyn M Wyse, Abigail N VandeWalle, Eric V Anslyn, Nicholas A Peppas.
Abstract
An aldehyde acrylate-based functional monomer was incorporated into poly(N-isopropylacrylamide-co-methacrylic acid) nanogels for use as protein receptors. The aldehyde component forms dynamic imines with surface exposed lysine residues, while carboxylic acid/carboxylate moieties form electrostatic interactions with high isoelectric point proteins. Together, these interactions effect protein adsorption and recognition.Entities:
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Year: 2020 PMID: 32364214 PMCID: PMC7377432 DOI: 10.1039/d0cc02200d
Source DB: PubMed Journal: Chem Commun (Camb) ISSN: 1359-7345 Impact factor: 6.222