Literature DB >> 32364214

Nanogel receptors for high isoelectric point protein detection: influence of electrostatic and covalent polymer-protein interactions.

Marissa E Wechsler1, H K H Jocelyn Dang, Samuel D Dahlhauser, Susana P Simmonds, James F Reuther, Jordyn M Wyse, Abigail N VandeWalle, Eric V Anslyn, Nicholas A Peppas.   

Abstract

An aldehyde acrylate-based functional monomer was incorporated into poly(N-isopropylacrylamide-co-methacrylic acid) nanogels for use as protein receptors. The aldehyde component forms dynamic imines with surface exposed lysine residues, while carboxylic acid/carboxylate moieties form electrostatic interactions with high isoelectric point proteins. Together, these interactions effect protein adsorption and recognition.

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Year:  2020        PMID: 32364214      PMCID: PMC7377432          DOI: 10.1039/d0cc02200d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  25 in total

1.  Inference of macromolecular assemblies from crystalline state.

Authors:  Evgeny Krissinel; Kim Henrick
Journal:  J Mol Biol       Date:  2007-05-13       Impact factor: 5.469

Review 2.  Functional systems with orthogonal dynamic covalent bonds.

Authors:  Adam Wilson; Giulio Gasparini; Stefan Matile
Journal:  Chem Soc Rev       Date:  2014-03-21       Impact factor: 54.564

Review 3.  Tunable Orthogonal Reversible Covalent (TORC) Bonds: Dynamic Chemical Control over Molecular Assembly.

Authors:  James F Reuther; Samuel D Dahlhauser; Eric V Anslyn
Journal:  Angew Chem Int Ed Engl       Date:  2018-10-30       Impact factor: 15.336

4.  Thermoresponsive dynamic covalent single-chain polymer nanoparticles reversibly transform into a hydrogel.

Authors:  Daniel E Whitaker; Clare S Mahon; David A Fulton
Journal:  Angew Chem Int Ed Engl       Date:  2012-12-06       Impact factor: 15.336

5.  Nucleophilic catalysis of acylhydrazone equilibration for protein-directed dynamic covalent chemistry.

Authors:  Venugopal T Bhat; Anne M Caniard; Torsten Luksch; Ruth Brenk; Dominic J Campopiano; Michael F Greaney
Journal:  Nat Chem       Date:  2010-05-16       Impact factor: 24.427

6.  Hydrogel nanoparticle harvesting of plasma or urine for detecting low abundance proteins.

Authors:  Ruben Magni; Benjamin H Espina; Lance A Liotta; Alessandra Luchini; Virginia Espina
Journal:  J Vis Exp       Date:  2014-08-07       Impact factor: 1.355

7.  Chemical functionalization of oligodeoxynucleotides with multiple boronic acids for the polyvalent binding of saccharides.

Authors:  Amanda E Hargrove; Andrew D Ellington; Eric V Anslyn; Jonathan L Sessler
Journal:  Bioconjug Chem       Date:  2011-02-07       Impact factor: 4.774

8.  Analyte-Responsive Hydrogels: Intelligent Materials for Biosensing and Drug Delivery.

Authors:  Heidi R Culver; John R Clegg; Nicholas A Peppas
Journal:  Acc Chem Res       Date:  2017-02-07       Impact factor: 22.384

Review 9.  Template-directed synthesis employing reversible imine bond formation.

Authors:  Cari D Meyer; C Steven Joiner; J Fraser Stoddart
Journal:  Chem Soc Rev       Date:  2007-11       Impact factor: 54.564

10.  Label-Free Detection of Tear Biomarkers Using Hydrogel-Coated Gold Nanoshells in a Localized Surface Plasmon Resonance-Based Biosensor.

Authors:  Heidi R Culver; Marissa E Wechsler; Nicholas A Peppas
Journal:  ACS Nano       Date:  2018-09-14       Impact factor: 15.881

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  1 in total

Review 1.  Application of Protein in Extrusion-Based 3D Food Printing: Current Status and Prospectus.

Authors:  Ziang Guo; Muhammad Arslan; Zhihua Li; Shaoyi Cen; Jiyong Shi; Xiaowei Huang; Jianbo Xiao; Xiaobo Zou
Journal:  Foods       Date:  2022-06-27
  1 in total

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