| Literature DB >> 30098086 |
James F Reuther1,2, Samuel D Dahlhauser1, Eric V Anslyn1.
Abstract
Dynamic assembly of macromolecules in biological systems is one of the fundamental processes that facilitates life. Although such assembly most commonly uses noncovalent interactions, a set of dynamic reactions involving reversible covalent bonding is actively being exploited for the design of functional materials, bottom-up assembly, and molecular machines. This Minireview highlights recent implementations and advancements in the area of tunable orthogonal reversible covalent (TORC) bonds for these purposes, and provides an outlook for their expansion, including the development of synthetically encoded polynucleotide mimics.Entities:
Keywords: dynamic covalent chemistry; dynamic materials; molecular assembly; molecular recognition; orthogonality
Year: 2018 PMID: 30098086 DOI: 10.1002/anie.201808371
Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN: 1433-7851 Impact factor: 15.336