Literature DB >> 32345713

Is there an antagonistic pleiotropic effect of a LRRK2 mutation on leprosy and Parkinson's disease?

Deng-Feng Zhang1, Dong Wang2, Yu-Ye Li3, Yong-Gang Yao1,4,5.   

Abstract

Entities:  

Year:  2020        PMID: 32345713      PMCID: PMC7229648          DOI: 10.1073/pnas.2000533117

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


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  9 in total

1.  Leprosy type 1 reaction (formerly reversal reaction).

Authors:  Bernard Naafs; Colette L M van Hees
Journal:  Clin Dermatol       Date:  2015-11-11       Impact factor: 3.541

Review 2.  Systemic infections and inflammation affect chronic neurodegeneration.

Authors:  V Hugh Perry; Colm Cunningham; Clive Holmes
Journal:  Nat Rev Immunol       Date:  2007-01-15       Impact factor: 53.106

3.  Missense Variants in HIF1A and LACC1 Contribute to Leprosy Risk in Han Chinese.

Authors:  Dong Wang; Yu Fan; Mahadev Malhi; Rui Bi; Yong Wu; Min Xu; Xiu-Feng Yu; Heng Long; Yu-Ye Li; Deng-Feng Zhang; Yong-Gang Yao
Journal:  Am J Hum Genet       Date:  2018-04-26       Impact factor: 11.025

4.  Association of the LRRK2 genetic polymorphisms with leprosy in Han Chinese from Southwest China.

Authors:  D Wang; L Xu; L Lv; L-Y Su; Y Fan; D-F Zhang; R Bi; D Yu; W Zhang; X-A Li; Y-Y Li; Y-G Yao
Journal:  Genes Immun       Date:  2014-12-18       Impact factor: 2.676

Review 5.  The role of leucine-rich repeat kinase 2 (LRRK2) in Parkinson's disease.

Authors:  Mark R Cookson
Journal:  Nat Rev Neurosci       Date:  2010-11-19       Impact factor: 34.870

6.  Analysis of Lrrk2 R1628P as a risk factor for Parkinson's disease.

Authors:  Owen A Ross; Yih-Ru Wu; Mei-Ching Lee; Manabu Funayama; Meng-Ling Chen; Alexandra I Soto; Ignacio F Mata; Guey-Jen Lee-Chen; Chiung Mei Chen; Michelle Tang; Yi Zhao; Nobutaka Hattori; Matthew J Farrer; Eng-King Tan; Ruey-Meei Wu
Journal:  Ann Neurol       Date:  2008-07       Impact factor: 10.422

7.  Complement C7 is a novel risk gene for Alzheimer's disease in Han Chinese.

Authors:  Deng-Feng Zhang; Yu Fan; Min Xu; Guihong Wang; Dong Wang; Jin Li; Li-Li Kong; Hejiang Zhou; Rongcan Luo; Rui Bi; Yong Wu; Guo-Dong Li; Ming Li; Xiong-Jian Luo; Hong-Yan Jiang; Liwen Tan; Chunjiu Zhong; Yiru Fang; Chen Zhang; Nengyin Sheng; Tianzi Jiang; Yong-Gang Yao
Journal:  Natl Sci Rev       Date:  2018-11-05       Impact factor: 17.275

8.  Pleiotropic effects for Parkin and LRRK2 in leprosy type-1 reactions and Parkinson's disease.

Authors:  Vinicius M Fava; Yong Zhong Xu; Guillaume Lettre; Nguyen Van Thuc; Marianna Orlova; Vu Hong Thai; Shao Tao; Nathalie Croteau; Mohamed A Eldeeb; Emma J MacDougall; Geison Cambri; Ramanuj Lahiri; Linda Adams; Edward A Fon; Jean-François Trempe; Aurélie Cobat; Alexandre Alcaïs; Laurent Abel; Erwin Schurr
Journal:  Proc Natl Acad Sci U S A       Date:  2019-07-15       Impact factor: 11.205

9.  Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation.

Authors:  Joshua C Bis; Xueqiu Jian; Brian W Kunkle; Yuning Chen; Adam C Naj; Myriam Fornage; Lindsay A Farrer; Kara L Hamilton-Nelson; William S Bush; William J Salerno; Daniel Lancour; Yiyi Ma; Alan E Renton; Edoardo Marcora; John J Farrell; Yi Zhao; Liming Qu; Shahzad Ahmad; Najaf Amin; Philippe Amouyel; Gary W Beecham; Jennifer E Below; Dominique Campion; Laura Cantwell; Camille Charbonnier; Jaeyoon Chung; Paul K Crane; Carlos Cruchaga; L Adrienne Cupples; Jean-François Dartigues; Stéphanie Debette; Jean-François Deleuze; Lucinda Fulton; Stacey B Gabriel; Emmanuelle Genin; Richard A Gibbs; Alison Goate; Benjamin Grenier-Boley; Namrata Gupta; Jonathan L Haines; Aki S Havulinna; Seppo Helisalmi; Mikko Hiltunen; Daniel P Howrigan; M Arfan Ikram; Jaakko Kaprio; Jan Konrad; Amanda Kuzma; Eric S Lander; Mark Lathrop; Terho Lehtimäki; Honghuang Lin; Kari Mattila; Richard Mayeux; Donna M Muzny; Waleed Nasser; Benjamin Neale; Kwangsik Nho; Gaël Nicolas; Devanshi Patel; Margaret A Pericak-Vance; Markus Perola; Bruce M Psaty; Olivier Quenez; Farid Rajabli; Richard Redon; Christiane Reitz; Anne M Remes; Veikko Salomaa; Chloe Sarnowski; Helena Schmidt; Michael Schmidt; Reinhold Schmidt; Hilkka Soininen; Timothy A Thornton; Giuseppe Tosto; Christophe Tzourio; Sven J van der Lee; Cornelia M van Duijn; Otto Valladares; Badri Vardarajan; Li-San Wang; Weixin Wang; Ellen Wijsman; Richard K Wilson; Daniela Witten; Kim C Worley; Xiaoling Zhang; Celine Bellenguez; Jean-Charles Lambert; Mitja I Kurki; Aarno Palotie; Mark Daly; Eric Boerwinkle; Kathryn L Lunetta; Anita L Destefano; Josée Dupuis; Eden R Martin; Gerard D Schellenberg; Sudha Seshadri
Journal:  Mol Psychiatry       Date:  2018-08-14       Impact factor: 15.992

  9 in total
  1 in total

1.  Reply to Zhang et al.: The differential role of LRRK2 variants in nested leprosy phenotypes.

Authors:  Vinicius M Fava; Aurélie Cobat; Chaïma Gzara; Alexandre Alcaïs; Laurent Abel; Erwin Schurr
Journal:  Proc Natl Acad Sci U S A       Date:  2020-04-28       Impact factor: 11.205

  1 in total

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